The epidemiology of the systemic inflammatory response

Definitions for Sepsis and Organ Failure and Guidelines for the Use of Innovative Therapies in Sepsis

1992 • 12,726 citations

The American-European Consensus Conference on ARDS. Definitions, mechanisms, relevant outcomes, and clinical trial coordination.

1994 • 6,682 citations

A new Simplified Acute Physiology Score (SAPS II) based on a European/North American multicenter study

1993 • 6,337 citations

A New Simplified Acute Physiology Score (SAPS II) Based on a European/North American Multicenter Study

1993 • 5,263 citations

Use of the SOFA score to assess the incidence of organ dysfunction/failure in intensive care units

1998 • 3,133 citations

Multiple Organ Dysfunction Score

1995 • 2,453 citations

The Natural History of the Systemic Inflammatory Response Syndrome (SIRS)

1995 • 2,007 citations

Gram-negative bacteremia

1980 • 1,341 citations

Prognosis in Acute Organ-System Failure

1985 • 1,248 citations

Incidence, risk factors, and outcome of severe sepsis and septic shock in adults. A multicenter prospective study in intensive care units. French ICU Group for Severe Sepsis

1995 • 886 citations

The Logistic Organ Dysfunction System

1996 • 726 citations

Epidemiology of Sepsis Syndrome in 8 Academic Medical Centers

1997 • 662 citations

The Logistic Organ Dysfunction system. A new way to assess organ dysfunction in the intensive care unit. ICU Scoring Group

1996 • 550 citations

Nosocomial Bloodstream Infections

1995 • 500 citations

American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference definitions of the systemic inflammatory response syndrome and allied disorders in relation to critically injured patients

1997 • 384 citations

Bacteremia and severe sepsis in adults: a multicenter prospective survey in ICUs and wards of 24 hospitals. French Bacteremia-Sepsis Study Group.

1996 • 336 citations

Systemic inflammatory response syndrome, sepsis, severe sepsis and septic shock: Incidence, morbidities and outcomes in surgical ICU patients

1995 • 331 citations

Long-term Survival and Function After Suspected Gram-negative Sepsis

1995 • 308 citations

The Italian SEPSIS study: Preliminary results on the incidence and evolution of SIRS, sepsis, severe sepsis and septic shock

1995 • 257 citations

Bedside prediction of mortality from bacteremic sepsis. A dynamic analysis of ICU patients.

1996 • 217 citations

The Clinical Evaluation of New Drugs for Sepsis

1993 • 202 citations

Predicting Bacteremia in Patients with Sepsis Syndrome

1997 • 201 citations

Importance of pre-existing co-morbidities for prognosis of septicemia in critically ill patients

1993 • 183 citations

Customized probability models for early severe sepsis in adult intensive care patients. Intensive Care Unit Scoring Group.

1995 • 171 citations

Long-term survival after intensive care unit admission with sepsis

1995 • 159 citations

Nosocomial bloodstream infections. Secular trends in rates, mortality, and contribution to total hospital deaths

1995 • 114 citations

Increase in National Hospital Discharge Survey Rates for Septicemia— United States, 1979-1987

1990 • 108 citations

The Sepsis Syndrome in a Dutch University Hospital

1993 • 100 citations

Role of systemic inflammatory response syndrome and infection in the occurrence of early multiple organ dysfunction syndrome following severe trauma

1995 • 87 citations

The Dynamics of Disease Progression in Sepsis: Markov Modeling Describing the Natural History and the Likely Impact of Effective Antisepsis Agents

1998 • 86 citations

Long-term survival and function after suspected gram-negative sepsis

1995 • 49 citations

Gram-negative bacteremia. IV. Re-evaluation of clinical features and treatment in 612 patients

1980 • 45 citations

The clinical evaluation of new drugs for sepsis. A prospective study design based on survival analysis

1993 • 43 citations

The sepsis syndrome in a Dutch university hospital. Clinical observations

1993 • 26 citations