The Role of CRF in Behavioral Aspects of Stress

Characterization of a 41-Residue Ovine Hypothalamic Peptide that Stimulates Secretion of Corticotropin and β-Endorphin

1982 • 3,896 citations

Physiological Functions of Glucocorticoids in Stress and Their Relation to Pharmacological Actions*

1984 • 3,073 citations

Organization of Ovine Corticotropin-Releasing Factor Immunoreactive Cells and Fibers in the Rat Brain: An Immunohistochemical Study

1983 • 1,954 citations

Physiological and behavioral responses to corticotropin-releasing factor administration: is CRF a mediator of anxiety or stress responses?

1990 • 1,362 citations

Corticotropin releasing factor produces behavioural activation in rats

1982 • 752 citations

Synthetic Competitive Antagonists of Corticotropin-Releasing Factor: Effect on ACTH Secretion in the Rat

1984 • 474 citations

A re-evaluation of the concept of ‘non-specificity’ in stress theory

1971 • 472 citations

Alterations in corticotropin-releasing factor-like immunoreactivity in discrete rat brain regions after acute and chronic stress

1986 • 466 citations

Overproduction of corticotropin-releasing factor in transgenic mice: a genetic model of anxiogenic behavior

1994 • 462 citations

Differential regulation of corticotropin-releasing factor mRNA in rat brain regions by glucocorticoids and stress

1991 • 434 citations

Cloning and functional expression of a rat brain corticotropin releasing factor (CRF) receptor.

1993 • 414 citations

Corticotropin-releasing factor produces fear-enhancing and behavioral activating effects following infusion into the locus coeruleus

1990 • 400 citations

CRF antagonist reverses the “anxiogenic” response to ethanol withdrawal in the rat

1991 • 357 citations

Corticotropin-releasing factor receptors in the rat central nervous system: characterization and regional distribution

1987 • 339 citations

Corticotropin-releasing factor antagonist reduces emotionality in socially defeated rats via direct neurotropic action

1992 • 333 citations

Recombinant Toxins for Cancer Treatment

1991 • 308 citations

CRF antagonist partially reverses CRF- and stress-induced effects on feeding

1986 • 302 citations

Behavioral effects of corticotropin-releasing factor: localization and characterization of central effects

1988 • 267 citations

Corticotropin-Releasing Factor : Basic and Clinical Studies of a Neuropeptide

2018 • 249 citations

The Stress Response: A New Perspective

1979 • 238 citations

Attenuation of stress-induced behavior by antagonism of corticotropin-releasing factor receptors in the central amygdala in the rat

1993 • 198 citations

Corticotropin-releasing factor modulates defensive-withdrawal and exploratory behavior in rats.

1989 • 190 citations

Amygdaloid Lesions: Differential Effect on Conditioned Stress and Immobilization-Induced Increases in Corticosterone and Renin Secretion

1991 • 187 citations

Evidence for differential regulation of corticotropin-releasing factor and vasopressin immunoreactivities in parvocellular neurosecretory and autonomic-related projections of the paraventricular nucleus

1987 • 182 citations

Intra-amygdala injections of corticotropin releasing factor facilitate inhibitory avoidance learning and reduce exploratory behavior in rats

1988 • 176 citations

Corticotropin-releasing factor modulates defensive-withdrawal and exploratory behavior in rats.

1989 • 171 citations

Corticotropin-Releasing Factor: Evidence for a Neurotransmitter Role in the Locus ceruleus during Hemodynamic Stress

1988 • 157 citations

Membrane attack by complement

1984 • 156 citations

Control of ACTH Secretion by the Central Nucleus of the Amygdala: Implication of the Serotoninergic System and Its Relevance to the Glucocorticoid Delayed Negative Feedback Mechanism

1986 • 153 citations

Corticotropin-releasing factor antagonist blocks stress-induced fighting in rats

1987 • 148 citations

Effects of corticotropin releasing factor on locomotor activity in hypophysectomized rats

1985 • 145 citations

Anti-Stress Action of a Corticotropin-Releasing Factor Antagonist on Behavioral Reactivity to Stressors of Varying Type and Intensity

1994 • 142 citations

Neurochemical and behavioral effects of corticotropin-releasing factor in the ventral tegmental area of the rat.

1987 • 140 citations

A corticotropin-releasing factor antagonist reverses the stress-induced changes of exploratory behavior in mice

1987 • 118 citations

Central administration of a CRF antagonist blocks the development of stress-induced behavioral sensitization

1990 • 108 citations

Dexamethasone suppresses pituitary-adrenal but not behavioral effects of centrally administered CRF

1986 • 98 citations

Endogenous corticotropin-releasing factor modulates feeding induced by neuropeptide Y or a tail-pinch stressor

1992 • 96 citations

Central administration of corticotropin releasing factor induces long-term sensitization to d-amphetamine

1993 • 90 citations

Blockade of pituitary-adrenal axis activation induced by peripheral immunoneutralization of corticotropin-releasing factor does not affect the behavioral response to social defeat stress in rats

1993 • 84 citations

CRF in the paraventricular nucleus of the hypothalamus induces dose-related behavioral profile in rats

1992 • 82 citations

Corticotropin-releasing factor induces a place aversion independent of its neuroendocrine role

1992 • 72 citations

The effects of ICV-CRH on novelty-induced behavior

1987 • 67 citations

Functional impairment of hypothalamic corticotropin-releasing factor neurons with immunotargeted toxins enhances food intake induced by neuropeptide Y

1993 • 67 citations

Effect of corticotropin-releasing factor antagonist on behavioral and neuroendocrine responses during exposure to defensive burying paradigm in rats

1994 • 63 citations

Behavioral activation by CRF: Evidence for the involvement of the ventral forebrain

1987 • 61 citations

Role of Endogenous Corticotropin Releasing Factor in Mediation of Neuroendocrine and Behavioral Responses to Cholecystokinin Octapeptide Sulfate Ester in Rats

1993 • 60 citations

Treatment with α-helical-CRF(9–41) prevents the anorectic effect of 17-β-estradiol

1993 • 57 citations

Corticotropin-releasing factor release from the mediobasal hypothalamus of the rat as measured by microdialysis

1993 • 57 citations

Behavioral Effects of Corticotropin-Releasing Factor

1990 • 56 citations

Both conditioned taste preference and aversion induced by corticotropin-releasing factor

1991 • 46 citations

Corticotropin-releasing factor modulates dietary preference in nutritionally and physically stressed rats

1992 • 44 citations

Intrahypothalamic microinfusion of corticotropin-releasing factor inhibits gastric acid secretion but increases secretion volume in rats

1987 • 43 citations

Involvement of hypothalamic corticotropin-releasing factor neurons in behavioral responses to novelty in rats

1994 • 38 citations

Uptake of a monoclonal antibody to corticotropin-releasing factor (CRF) into rat hypothalamic neurons

1990 • 18 citations

Psychopharmacological activity of immune complexes in rat brain is complement dependent

1987 • 17 citations

Long‐Term Inhibition of Stress‐Induced Adrenocorticotropin Release by Intracerebral Administration of a Monoclonal Antibody to Rat Corticotropin‐Releasing Factor Together with Ricin A Chain and Monensin

1991 • 14 citations