Promoting Functional Plasticity in the Damaged Nervous System

CHEMOAFFINITY IN THE ORDERLY GROWTH OF NERVE FIBER PATTERNS AND CONNECTIONS

1963 • 1,947 citations

Axonal Elongation into Peripheral Nervous System "Bridges" After Central Nervous System Injury in Adult Rats

1981 • 1,679 citations

Regressive Events in Neurogenesis

1984 • 1,330 citations

An index of the functional condition of rat sciatic nerve based on measurements made from walking tracks

1982 • 1,117 citations

Cell Adhesion Molecules

1983 • 1,017 citations

Brain Grafts Reduce Motor Abnormalities Produced by Destruction of Nigrostriatal Dopamine System

1979 • 963 citations

Biosynthesis and Function of Gangliosides

1976 • 748 citations

KIDNEY PRESERVATION FOR TRANSPORTATION

1969 • 716 citations

Trophic Interactions Between Astroglial Cells and Hippocampal Neurons in Culture

1980 • 672 citations

Reinnervation of the denervated striatum by substantia nigra transplants: Functional consequences as revealed by pharmacological and sensorimotor testing

1980 • 551 citations

Synapse replacement in the nervous system of adult vertebrates.

1981 • 545 citations

Nerve growth factor, laminin, and fibronectin promote neurite growth in human fetal sensory ganglia cultures

1982 • 541 citations

Recording action potentials from cultured neurons with extracellular microcircuit electrodes

1980 • 540 citations

Glial cells and the central myelin sheath.

1968 • 530 citations

Neuronal Chemotaxis: Chick Dorsal-Root Axons Turn Toward High Concentrations of Nerve Growth Factor

1979 • 522 citations

Schwann cell basal lamina and nerve regeneration

1983 • 511 citations

Nerve growth factor-induced fiber outgrowth from isolated rat adrenal chromaffin cells: impairment by glucocorticoids.

1978 • 468 citations

Chronic intraventricular injections of nerve growth factor elevate hippocampal choline acetyltransferase activity in adult rats with partial septo-hippocampal lesions

1984 • 446 citations

Extensive elongation of axons from rat brain into peripheral nerve grafts

1982 • 436 citations

Artificial Vision for the Blind: Electrical Stimulation of Visual Cortex Offers Hope for a Functional Prosthesis

1974 • 427 citations

Transplanted adrenal chromaffin cells in rat brain reduce lesion-induced rotational behaviour

1981 • 415 citations

Septal transplants restore maze learning in rats with fornix-fimbria lesions

1982 • 414 citations

Gonadal Hormones Induce Dendritic Growth in the Adult Avian Brain

1981 • 393 citations

Injury-induced neuronotrophic activity in adult rat brain: correlation with survival of delayed implants in the wound cavity

1983 • 389 citations

Cell Recognition During Neuronal Development

1984 • 381 citations

Restitution of function and collateral sprouting in the cat spinal cord: The partially hemisected animal

1974 • 376 citations

Regeneration of monoaminergic and cholinergic neurons in the mammalian central nervous system

1979 • 374 citations

Intrahippocampal Septal Grafts Ameliorate Learning Impairments in Aged Rats

1984 • 369 citations

Influence of Rehabilitation on Language Skills in Aphasic Patients

1979 • 368 citations

Restoration of dopaminergic function by grafting of fetal rat substantia nigra to the caudate nucleus: Long‐term behavioral, biochemical, and histochemical studies

1980 • 340 citations

Trophic Mechanisms in the Peripheral Nervous System

1978 • 326 citations

The direction of growth of differentiating neurones and myoblasts from frog embryos in an applied electric field.

1981 • 326 citations

Neurites grow faster towards the cathode than the anode in a steady field

1979 • 319 citations

Plasticity in the spinal cord sensory map following peripheral nerve injury in rats

1981 • 291 citations

Developmental Neurobiology and the Natural History of Nerve Growth Factor

1982 • 289 citations

Is it really better to have your brain lesion early? a revision of the “Kennard Principle”

1979 • 288 citations

Cell Biology of Synaptic Plasticity

1984 • 275 citations

Studies of Schwann cell proliferation. II. Characterization of the stimulation and specificity of the response to a neurite membrane fraction.

1980 • 270 citations

Brain grafts reverse hypogonadism of gonadotropin releasing hormone deficiency

1982 • 265 citations

Functional reinnervation of the neostriatum in the adult rat by use of intraparenchymal grafting of dissociated cell suspensions from the substantia nigra

1980 • 259 citations

GM1 ganglioside stimulates the regeneration of dopaminergic neurons in the central nervous system

1983 • 255 citations

Gangliosides enhance neurite outgrowth in PC12 cells

1983 • 249 citations

Regeneration of the septohippocampal pathways in adult rats is promoted by utilizing embryonic hippocampal implants as bridges

1981 • 249 citations

Induction of neurite outgrowth by a conditioned-medium factor bound to the culture substratum

1978 • 245 citations

THE FUNCTIONAL REPAIR OF NERVOUS TISSUE

1942 • 242 citations

Alteration in Connections Between Muscle and Anterior Horn Motoneurons After Peripheral Nerve Repair

1980 • 231 citations

Studies on the control of myelinogenesis. II. Evidence for neuronal regulation of myelin production

1976 • 228 citations

Promotion of retinal neurite outgrowth by substratum-bound fibronectin

1981 • 222 citations

Gangliosides increase the survival of lesioned nigral dopamine neurons and favour the recovery of dopaminergic synaptic function in striatum of rats by collateral sprouting*

1983 • 218 citations

Peripheral nerve autografts to the rat spinal cord: Studies with axonal tracing methods

1982 • 214 citations

Postnatally Induced Formation of the Corpus Callosum in Acallosal Mice on Glia-Coated Cellulose Bridges

1983 • 201 citations

Depletion of dopamine in the striatum as an experimental model of parkinsonism: direct effects and adaptive mechanisms

1982 • 201 citations

Enhanced Spinal Cord Regeneration in Lamprey by Applied Electric Fields

1981 • 201 citations

Neuronotrophic activity in brain wounds of the developing rat. Correlation with implant survival in the wound cavity

1983 • 197 citations

Functional brain tissue transplantation: reversal of lesion-induced rotation by intraventricular substantia nigra and adrenal medulla grafts, with a note on intracranial retinal grafts.

1983 • 193 citations

The mechanisms of action of L-dopa in Parkinson's disease

1974 • 193 citations

Functional Development of Grafted Vasopressin Neurons

1980 • 193 citations

Muscle reinnervation—III. Motoneuron sprouting capacity, enhancement by exogenous gangliosides

1983 • 186 citations

The role of ependyma in regeneration of the spinal cord in the urodele amphibian tail

1978 • 184 citations

Characterization of the calcium-induced disruption of neurofilaments in rat peripheral nerve

1979 • 183 citations

In Vitro Evidence for Two Distinct Hippocampal Growth Factors: Basis of Neuronal Plasticity?

1982 • 177 citations

Fetal Brain Transplant: Reduction of Cognitive Deficits in Rats with Frontal Cortex Lesions

1983 • 175 citations

The Bioelectric Factors in Amphibian-Limb Regeneration

1961 • 175 citations

Sympathetic nerve fibers ingrowth in the central nervous system of neonatal rodent upon intracerebral NGF injections.

1978 • 173 citations

The possibility of structural and functional restitution after spinal cord injury. A review

1977 • 168 citations

Transplantation of brain tissue in the brain of rat. I. Growth characteristics of neocortical transplants from embryos of different ages

1980 • 162 citations

Aged Rats: Recovery of Motor Impairments by Intrastriatal Nigral Grafts

1983 • 162 citations

Electron-microscope observations on the effects of localized crush injuries on the connective tissues of peripheral nerve.

1968 • 161 citations

Laminin as a substrate for retinal axons in vitro

1984 • 152 citations

Transplantation of embryonic occipital cortex to the tectal region of newborn rats: A light microscopic study of organization and connectivity of the transplants

1980 • 149 citations

G _M1 Ganglioside Treatment Facilitates Behavioral Recovery from Bilateral Brain Damage

1984 • 148 citations

Competence of nerve tissue as distal insert promoting nerve regeneration in a silicone chamber

1984 • 145 citations

Specific projections of retina transplanted to rat brain

1980 • 142 citations

Adrenocortical control of the biosynthesis of epinephrine and proteins in the adrenal medulla.

1972 • 137 citations

Target neuron-specific process formation by embryonic mesencephalic dopamine neurons in vitro.

1981 • 135 citations

Extracts of Skeletal Muscle Increase Neurite Outgrowth and Cholinergic Activity of Fetal Rat Spinal Motor Neurons

1983 • 134 citations

FACTORS AFFECTING RECOVERY OF SENSORY FUNCTION AFTER NERVE LESIONS

1942 • 132 citations

Axonal regeneration and formation of synapses proximal to the site of lesion following hemisection of the rat spinal cord

1971 • 131 citations

Ganglioside treatment improves recovery of alternation behavior after unilateral entorhinal cortex lesion

1983 • 129 citations

Plasticity of the corticospinal tract following midthoracic spinal injury in the postnatal rat

1983 • 129 citations

Neuronal plasticity in the deafferented hypothalamic arcuate nucleus of adult female rats and its enhancement by treatment with estrogen

1981 • 129 citations

Normalization of Spiroperidol Binding in the Denervated Rat Striatum by Homologous Grafts of Substantia Nigra

1983 • 128 citations

Intracephalic embryonic neural implants in the adult rat brain. I. Growth and mature organization of birainstem, cerebellar, and hippocampal implants

1983 • 122 citations

Reinnervation of the denervated adult spinal cord of rats by intraspinal transplants of embryonic brain stem neurons

1983 • 122 citations

CHANGES IN THE ENDONEURIAL SHEATHS OF PERIPHERAL MYELINATED NERVE FIBRES DURING WALLERIAN DEGENERATION.

1964 • 121 citations

Neuronotrophic and Neurite-Promoting Factors and Their Clinical Potentials pp. 73–86

1983 • 118 citations

Synaptic Regeneration in Identified Neurons of the Lamprey Spinal Cords

1979 • 115 citations

Infant lesion effect: III. Anatomical correlates of sparing and recovery of function after spinal cord damage in newborn and adult cats

1983 • 114 citations

Early developmental events: cell lineages, acquisition of neuronal positions, and areal and laminar development.

1982 • 113 citations

Meganeurites and other aberrant processes of neurons in feline GM1-gangliosidosis: A golgi study

1978 • 113 citations

Differences between adult and neonatal rats in their astroglial response to spinal injury

1984 • 110 citations

How a Nerve Fiber Repairs Its Cut End: Involvement of Phospholipase A ₂

1983 • 109 citations

Recovery of Normal Topography in the Somatosensory Cortex of Monkeys After Nerve Crush and Regeneration

1983 • 109 citations

Adrènal medulla grafts survice and exhibit catecholamine-specific fluorescence in the primate brain

1984 • 108 citations

Forskolin activation of adenylate cyclase in vivo stimulates nerve regeneration

1984 • 104 citations

Electron microscopy of severed motor fibers in the crayfish

1972 • 101 citations

Monoaminergic reinnervation of the transected spinal cord by homologous fetal brain grafts

1977 • 100 citations

Adrenal medullary implants in the dopamine-denervated rat striatum. I. Acute catecholamine levels in grafts and host caudate as determined by HPLC-electrochemistry and fluorescence histochemical image analysis

1984 • 100 citations

Reduction of experimentally induced neuronal death in spinal ganglia of the chick embryo by nerve growth factor

1984 • 99 citations

FACTORS AFFECTING RECOVERY OF MOTOR FUNCTION AFTER NERVE LESIONS

1942 • 94 citations

Regeneration of ganglion cell axons in the adult mouse retina

1982 • 92 citations

Catecholamine content of intracerebral adrenal medulla grafts

1983 • 91 citations

Effect of dopamine agonists and antagonists on the electrical activity of substantia nigra neurons transplanted into the lateral ventricle of the rat

1981 • 91 citations

Peripheral nerve reconnection: Mechanical, thermal, and ionic conditions that promote the return of function

1983 • 90 citations

Activation of Dormant Genes in Specialized Cells

1984 • 88 citations

Comparison of healing process in transected spinal cords grafted with autogenous brain tissue, sciatic nerve, and nodose ganglion

1974 • 87 citations

Normal development and post-traumatic plasticity of corticospinal neurons in rats

1978 • 85 citations

Experimental regeneration in peripheral nerves and the spinal cord in laboratory animals exposed to a pulsed electromagnetic field

1976 • 85 citations

Effects of high-peak pulsed electromagnetic field on the degeneration and regeneration of the common peroneal nerve in rats

1983 • 83 citations

Motor neuron survival and neuritic extension from spinal cord explants induced by factors released from denervated muscle

1984 • 83 citations

Functional role of regrowing pyramidal tract fibers

1982 • 82 citations

Axonal-ependymal associations during early regeneration of the transected spinal cord inXenopus laevis tadpoles

1979 • 82 citations

Aspects of neural development.

1978 • 81 citations

History of central nervous system regeneration research

1975 • 81 citations

Connections made by transplants to the cerebral cortex of rat brains damaged in utero

1984 • 79 citations

Long-term effects of dexamethasone and nerve growth factor on adrenal medullary cells cultured from young adult rats

1982 • 79 citations

Development of fetal retina, tectum, and cortex transplanted to the superior colliculus of adult rats

1983 • 78 citations

Effects of nerve growth factor on behavioral recovery following caudate nucleus lesions in rats

1978 • 77 citations

A Randomized Prospective Comparison of Fascicular and Epineural Digital Nerve Repairs

1981 • 76 citations

Control of direction of growth during the elongation of neurites

1975 • 72 citations

Ineffectiveness of enzyme therapy on regeneration in the transected spinal cord of the rat

1980 • 71 citations

Reinnervation of peripheral nerve segments implanted into the rat central nervous system

1980 • 70 citations

Origin of the connective tissue scar in the transected rat spinal cord

1981 • 70 citations

Assessing the Functional Significance of Lesion-Induced Neuronal Plasticity

1982 • 70 citations

Neurotransmitter characteristics of brain grafts: Striatal and septal tissues form the same laminated input to the hippocampus

1983 • 70 citations

Will central nervous systems in the adult mammal regenerate after bypassing a lesion? A study in the mouse and chick visual systems

1980 • 67 citations

Neural stability, sparing, and behavioral recovery following brain damage.

1975 • 65 citations

A regenerating neurone in the leech can form an electrical synapse on its severed axon segment

1977 • 65 citations

Growth, differentiation, and viability of fetal rat cortical and spinal cord implants into adult rat spinal cord

1983 • 65 citations

An in vivo assay of neurotropic activity

1983 • 62 citations

Locomotor Activity and Axon Regeneration Following Spinal Cord Compression in Rats Treated with L-Thyroxine^*†

1967 • 62 citations

Increases in collateral axonal growth rostral to a thoracic hemisection in neonatal and weanling rat

1976 • 60 citations

Spontaneous regeneration of cut axons in adult rat brain

1982 • 60 citations

Nerve growth factor stimulates development of substance P in the embryonic spinal cord

1981 • 60 citations

Enhancement of Sexual Behavior in Female Rats by Neonatal Transplantation of Brain Tissue from Males

1982 • 59 citations

Evaluation of the effects of nerve growth factor and anti-nerve growth factor on the development of central catecholamine-containing neurons

1978 • 59 citations

Histopathological reactions and axonal regeneration in the transected spinal cord of hibernating squirrels

1981 • 57 citations

Chronic glucocorticoid therapy alters axon sprouting in the hippocampal dentate gyrus

1982 • 56 citations

Neural stability, sparing, and behavioral recovery following brain damage.

1975 • 54 citations

AXON SPROUTING INTO SEGMENTS OF RAT SPINAL CORD ADJACENT TO THE SITE OF A PREVIOUS TRANSECTION

1979 • 54 citations

NGF and Anti-NGF: Evidence against Effects on Fiber Growth in Locus coeruleus from Cultures of Perinatal CNS Tissues

1979 • 51 citations

Astrocytic development in fetal parietal cortex grafted to cerebral and cerebellar cortex of immature rats

1983 • 50 citations

Peripheral nerve reconnection: Improvement of long-term functional effects under simulated clinical conditions in the rat

1983 • 49 citations

Formation of synapses in the adult rat after injury: similarities and differences between a peripheral and a central nervous site

1977 • 49 citations

Studies in vitro and in vivo of the effects of chlorpromazine on rat liver lysosomes

1965 • 49 citations

Axon regeneration across the site of injury in the optic nerve of the newt Triturus pyrrhogaster

1977 • 47 citations

Peripheral nerve reconnection: Immediate histologic consequences of distributed mechanical support

1983 • 46 citations

Ganglioside-mediated enhancement of the cytoskeletal organization and activity in neuro-2a neuroblastoma cells

1984 • 46 citations

Histological changes after transection of the spinal cord of fetal and neonatal mice

1979 • 46 citations

Neuronotrophic activities in cerebrospinal fluid of head trauma patients

1984 • 40 citations

Use of an experimental autoimmune model to define nerve growth factor dependency of peripheral and central substance P-containing neurons in the rat

1981 • 39 citations

Ultrastructure of fetal spinal cord and cortex implants into adult rat spinal cord

1984 • 39 citations

Nerve growth factor produces a temporary facilitation of recovery from entorhinal cortex lesions

1983 • 38 citations

Functional recovery after lesions of the nervous system. II. Recovery of function after lesions of the central nervous system: history and prospects.

1974 • 36 citations

Vascular permeability and axonal regeneration in tissues autotransplanted into the brain

1980 • 35 citations

Peripheral nerve reconnection: Inhibition of early degenerative processes through the use of a novel fluid medium

1984 • 30 citations

Role of glycoproteins in neuronal differentiation

1983 • 27 citations

Effect of puromycin treatment on the regeneration of hemisected and transected rat spinal cord

1978 • 25 citations

Transplantation into the mammalian adult spinal cord

1982 • 25 citations

Evaluation of transected spinal cord regeneration in the rat

1984 • 24 citations

Transplantation of eyes to the adult rat brain: Histological findings and light-evoked potential response

1980 • 22 citations

Influence of grafted glia cells and host mossy fibers on anomalously migrated host granule cells surviving in cortical transplants

1982 • 21 citations

Nerve growth factor: effects on d-amphetamine-induced activity and brain monoamines

1979 • 21 citations

ELECTRICAL FIELDS, CALCIUM GRADIENTS, AND CELL GROWTH

1980 • 17 citations

Effects of gangliosides on the development of selective afferent connections within fetal mouse spinal cord explants

1983 • 15 citations

GM1 ganglioside does not stimulate reinnervation of the striatum by substantia Nigra grafts

1985 • 15 citations

Review of Current Status of Cochlear Prostheses

1982 • 14 citations

Nerve growth factor disrupts metabolism and behavioral performance of intact rats but does not affect recovery from hypothalamic lesions

1980 • 11 citations

Artifactual presence of β-nerve growth factor in adult mouse brain

1984 • 10 citations

Changes in adrenal dopamine concentration after metyrapone or acth administration: Implications for the regulation of dopamine beta-hydroxylase by glucocorticoids

1977 • 8 citations

Failure of central axonal regeneration after immunosuppressive treatment.

1979 • 7 citations

Newer Techniques in Peripheral Nerve Repair

1977 • 6 citations

Cellular interactions in Schwann cell development.

1981 • 5 citations

Heart conditioned medium elicits post-lesion muscarinic receptor recovery in vivo

1983 • 2 citations

Deleted Work

1955 • 0 citations