Dynamics of Calcium Clearance in Mouse Pancreatic β-Cells

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

Functional comparisons between isoforms of the sarcoplasmic or endoplasmic reticulum family of calcium pumps.

1992 • 649 citations

Mitochondrial glutamate acts as a messenger in glucose-induced insulin exocytosis

1999 • 501 citations

Calcium and delayed potassium currents in mouse pancreatic beta‐cells under voltage‐clamp conditions.

1986 • 370 citations

The preparation of, and studies on, free cell suspensions from mouse pancreatic islets

1974 • 359 citations

Dominant Role of Mitochondria in Clearance of Large Ca2+ Loads from Rat Adrenal Chromaffin Cells

1996 • 352 citations

Protein kinase A‐dependent and ‐independent stimulation of exocytosis by cAMP in mouse pancreatic B‐cells

1997 • 302 citations

A Role for Malonyl-CoA in Glucose-Stimulated Insulin Secretion from Clonal Pancreatic β-Cells

1989 • 259 citations

Insulin-stimulated Insulin Secretion in Single Pancreatic Beta Cells

1999 • 216 citations

Direct measurement of proton transfer rates to a group controlling the dihydropyridine-sensitive Ca2+ channel

1987 • 201 citations

PKC-Dependent Stimulation of Exocytosis by Sulfonylureas in Pancreatic β Cells

1996 • 196 citations

Activation of protein kinases and inhibition of protein phosphatases play a central role in the regulation of exocytosis in mouse pancreatic beta cells.

1994 • 186 citations

Nutrient–secretion coupling in the pancreatic islet β-cell: recent advances

2001 • 184 citations

Acute Stimulation with Long Chain Acyl-CoA Enhances Exocytosis in Insulin-secreting Cells (HIT T-15 and NMRI β-Cells)

2000 • 173 citations

Roles of Insulin Receptor Substrate-1, Phosphatidylinositol 3-Kinase, and Release of Intracellular Ca2+ Stores in Insulin-stimulated Insulin Secretion in β-Cells

2000 • 164 citations

Allosteric Regulation of Na/Ca Exchange Current by Cytosolic Ca in Intact Cardiac Myocytes

2001 • 161 citations

Glucose-stimulated insulin secretion correlates with changes in mitochondrial and cytosolic Ca2+ in aequorin-expressing INS-1 cells.

1996 • 144 citations

Uptake and Release of Ca2+ by the Endoplasmic Reticulum Contribute to the Oscillations of the Cytosolic Ca2+ Concentration Triggered by Ca2+ Influx in the Electrically Excitable Pancreatic B-cell

1999 • 129 citations

Isoforms of endoplasmic reticulum Ca2+-ATPase are differentially expressed in normal and diabetic islets of Langerhans

1996 • 119 citations

Ca2+-induced Ca2+ Release from the Endoplasmic Reticulum Amplifies the Ca2+ Signal Mediated by Activation of Voltage-gated L-type Ca2+ Channels in Pancreatic β-Cells

2001 • 90 citations

A fluorimetric and amperometric study of calcium and secretion in isolated mouse pancreatic ?-cells

1995 • 79 citations

Glucose-induced Oscillations in Cytoplasmic Free Ca2+Concentration Precede Oscillations in Mitochondrial Membrane Potential in the Pancreatic β-Cell

2001 • 75 citations

Storemoperated Ca2+ entry in insulin-releasing pancreatic β-cells

1997 • 65 citations

Store-operated influx of Ca2+ in pancreatic β-cells exhibits graded dependence on the filling of the endoplasmic reticulum

2001 • 63 citations

Use of La3+ to distinguish activity of the plasmalemmal Ca2+ pump from Na+/Ca2+ exchange in arterial myocytes

1997 • 58 citations

Inactivation kinetics and pharmacology distinguish two calcium currents in mouse pancreatic B-cells

1991 • 53 citations

Significance of Na/Ca Exchange for Ca2+ Buffering and Electrical Activity in Mouse Pancreatic β-Cells

1999 • 48 citations

Expression of multiple plasma membrane Ca2+-ATPases in rat pancreatic islet cells

2000 • 46 citations

Fast and cAMP-Sensitive Mode of Ca2+-Dependent Exocytosis in Pancreatic β-Cells

2002 • 44 citations

Paradoxical block of the Na⁺‐Ca²⁺ exchanger by extracellular protons in guinea‐pig ventricular myocytes

2000 • 43 citations

A unique combination of plasma membrane Ca2+-ATPase isoforms is expressed in islets of Langerhans and pancreatic β-cell lines

1996 • 35 citations

Identification, expression pattern and potential activity of Na/Ca exchanger isoforms in rat pancreatic B-cells

1997 • 34 citations

Rapid fabrication of plastic-insulated carbon-fiber electrodes for micro-amperometry

1999 • 29 citations

Characterisation of endoplasmic reticulum and plasma membrane Ca2+-ATPases in pancreatic β-cells and in islets of Langerhans

1995 • 24 citations

Probing the extracellular release site of the plasma membrane calcium pump

2000 • 16 citations

Changes in 2′,7′-bis(carboxyethyl) 5′ (6′)-carboxyfluorescein-, fura-2 and autofluorescence in intact rat pancreatic islets in response to nutrients and non-nutrients

1995 • 11 citations