Regulation by phosphorylation of reversible association of a myristoylated protein kinase C substrate with the plasma membrane

The molecular heterogeneity of protein kinase C and its implications for cellular regulation

1988 • 4,243 citations

Inhibitory effect of a marine-sponge toxin, okadaic acid, on protein phosphatases. Specificity and kinetics

1988 • 1,699 citations

The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lck

1988 • 1,442 citations

Subcellular localization of the b-cytochrome component of the human neutrophil microbicidal oxidase: translocation during activation.

1983 • 938 citations

Effects of the tumour promoter okadaic acid on intracellular protein phosphorylation and metabolism

1989 • 848 citations

Phorbol esters, phospholipase C, and growth factors rapidly stimulate the phosphorylation of a Mr 80,000 protein in intact quiescent 3T3 cells.

1983 • 377 citations

Protein kinase C-stimulated phosphorylation in vitro of a Mr 80,000 protein phosphorylated in response to phorbol esters and growth factors in intact fibroblasts. Distinction from protein kinase C and prominence in brain.

1986 • 277 citations

Calcium/phospholipid regulates phosphorylation of a Mr "87k" substrate protein in brain synaptosomes.

1982 • 257 citations

Phosphorylation-regulated calmodulin binding to a prominent cellular substrate for protein kinase C

1989 • 241 citations

Stimulus-dependent myristoylation of a major substrate for protein kinase C

1988 • 216 citations

Activation of protein kinase C results in the displacement of its myristoylated, alanine-rich substrate from punctate structures in macrophage filopodia.

1990 • 195 citations

Two transduction sequences are necessary for neutrophil activation by receptor agonists.

1988 • 172 citations

Identification of a 32K plasma membrane protein that binds to the myristylated amino-terminal sequence of p60v-src

1990 • 162 citations

Specific and saturable binding of pp60v-src to plasma membranes: Evidence for a myristyl-src receptor

1989 • 137 citations

Tumor necrosis factor alpha modifies agonist-dependent responses in human neutrophils by inducing the synthesis and myristoylation of a specific protein kinase C substrate.

1990 • 95 citations

Myristoylated and Nonmyristoylated Forms of a Protein Are Phosphorylated by Protein Kinase C

1989 • 89 citations

Bacterial Lipopolysaccharide Regulates the Phosphorylation of the 68K Protein Kinase C Substrate in Macrophages

1989 • 64 citations