Intranuclear Translocation of Phospholipase C β2 during HL-60 Myeloid Differentiation

Inositol trisphosphate and calcium signalling

1993 • 6,546 citations

Induction of differentiation of the human promyelocytic leukemia cell line (HL-60) by retinoic acid.

1980 • 1,997 citations

The insulin signaling system.

1994 • 1,733 citations

Regulation of Polyphosphoinositide-specific Phospholipase C Activity by Purified G _q

1991 • 886 citations

PDGF stimulation of inositol phospholipid hydrolysis requires PLC-γ1 phosphorylation on tyrosine residues 783 and 1254

1991 • 583 citations

The retinoid signaling pathway: molecular and genetic analyses

1994 • 508 citations

The polyphosphoinositide cycle exists in the nuclei of Swiss 3T3 cells under the control of a receptor (for IGF-I) in the plasma membrane, and stimulation of the cycle increases nuclear diacylglycerol and apparently induces translocation of protein kinase

1991 • 454 citations

Nuclear localization and signalling activity of phosphoinositidase Cβ in Swiss 3T3 cells

1992 • 321 citations

Stimulation of phospholipase C by guanine‐nucleotide‐binding protein βγ subunits

1992 • 277 citations

Monoclonal antibodies to three phospholipase C isozymes from bovine brain.

1988 • 256 citations

Selective translocation of beta II-protein kinase C to the nucleus of human promyelocytic (HL60) leukemia cells.

1991 • 251 citations

Immunochemical evidence that three protein kinase C isozymes increase in abundance during HL-60 differentiation induced by dimethyl sulfoxide and retinoic acid.

1988 • 239 citations

Bovine brain cytosol contains three immunologically distinct forms of inositolphospholipid-specific phospholipase C.

1987 • 233 citations

Inositides and the nucleus and inositides in the nucleus

1993 • 209 citations

Phosphoinositide signalling enzymes in rat liver nuclei: phosphoinositidase C isoform β1 is specifically, but not predominantly, located in the nucleus

1993 • 165 citations

Activation of beta-isozyme of protein kinase C (PKC beta) is necessary and sufficient for phorbol ester-induced differentiation of HL-60 promyelocytes. Studies with PKC beta-defective PET mutant.

1994 • 135 citations

Bryostatin 1 activates protein kinase C and induces monocytic differentiation of HL-60 cells

1988 • 119 citations

Nuclear phosphatidylinositols decrease during S-phase of the cell cycle in HeLa cells.

1994 • 119 citations

Interleukin 1 alpha stimulates nuclear phospholipase C in human osteosarcoma SaOS-2 cells.

1994 • 108 citations

Phosphoinositide signaling in nuclei of Friend cells: phospholipase C beta down-regulation is related to cell differentiation.

1994 • 85 citations

Protein kinase C during differentiation of human promyelocytic leukemia cell line, HL‐60

1990 • 67 citations

Changes in the components of a nuclear inositide cycle during differentiation in murine erythroleukaemia cells

1995 • 62 citations

Nuclear translocation of protein kinase C‐α and ‐ζ isoforms in HL‐60 cells induced to differentiate along the granulocytic lineage by all‐trans retinoic acid

1996 • 61 citations

Discrete subcellular localization of phosphoinositidase C β, γ and δ in PC12 rat pheochromocytoma cells

1992 • 56 citations

Inositol lipid cycle in the nucleus

1994 • 48 citations

Identification of PI-PLC β1, γ1, and δ1 in rat liver: Subcellular distribution and relationship to inositol lipid nuclear signalling

1995 • 43 citations

Down-regulation of human protein kinase C alpha is associated with terminal neutrophil differentiation

1992 • 41 citations

Phospholipase C activates protein kinase C and induces monocytic differentiation of HL-60 cells

1988 • 31 citations

Inositides in nuclei of friend cells: Changes of polyphosphoinositide and diacylglycerol levels accompany cell differentiation

1995 • 29 citations

Potentiation of Gi-mediated Phospholipase C Activation by Retinoic Acid in HL-60 Cells

1995 • 28 citations

Heterogeneity of Protein Kinase C Isoform Expression in Chemically Induced HL60 Cells

1993 • 26 citations

Redistribution of DNA topoisomerase II β after in vitro stabilization of human erythroleukemic nuclei by heat or Cu++ revealed by confocal microscopy

1997 • 16 citations

Nuclear Scaffold Proteins Are Differently Sensitive to Stabilizing Treatment by Heat or Cu⁺⁺

1997 • 15 citations

Immunocytochemical analysis of phosphatidylinositol-specific phospholipase C in PC12 cells: predominance of the ? isoform during neural differentiation

1993 • 12 citations

Characterization of Nuclear Retinoic Acid-Binding Activity in Sensitive Leukemic-Cell Lines - Cell-Specific Uptake of Atra and Rarα Protein Modulation

1995 • 10 citations

Increased phosphorylation of nuclear substrates for rat brain protein kinase C in regenerating rat liver nuclei

1992 • 10 citations