Soluble syndecan-1 promotes growth of myeloma tumors in vivo

Functions of Cell Surface Heparan Sulfate Proteoglycans

1999 • 2,660 citations

Mammalian heparanase: Gene cloning, expression and function in tumor progression and metastasis

1999 • 788 citations

Syndecans: multifunctional cell-surface co-receptors

1997 • 676 citations

Membrane protein secretases

1997 • 634 citations

Cloning of mammalian heparanase, an important enzyme in tumor invasion and metastasis

1999 • 516 citations

Shedding of Syndecan-1 and -4 Ectodomains Is Regulated by Multiple Signaling Pathways and Mediated by a Timp-3–Sensitive Metalloproteinase

2000 • 409 citations

Syndecan-1 is required for Wnt-1-induced mammary tumorigenesis in mice

2000 • 366 citations

Physiological degradation converts the soluble syndecan-1 ectodomain from an inhibitor to a potent activator of FGF-2

1998 • 339 citations

Primary Myeloma Cells Growing in SCID-hu Mice: A Model for Studying the Biology and Treatment of Myeloma and Its Manifestations

1998 • 261 citations

Heparan sulfate proteoglycans in invasion and metastasis

2001 • 256 citations

Serum syndecan-1: a new independent prognostic marker in multiple myeloma

2000 • 241 citations

Expression of syndecan regulates human myeloma plasma cell adhesion to type I collagen

1993 • 230 citations

Syndecan-1 Is a Multifunctional Regulator of Myeloma Pathobiology: Control of Tumor Cell Survival, Growth, and Bone Cell Differentiation

1998 • 204 citations

Heparan sulfate proteoglycans from mouse mammary epithelial cells: localization on the cell surface with a monoclonal antibody.

1985 • 185 citations

Expression of syndecan-1 inhibits cell invasion into type I collagen.

1994 • 169 citations

The Development of a Model for the Homing of Multiple Myeloma Cells to Human Bone Marrow

1997 • 163 citations

Adaptation of the rapid automated tetrazolium dye based (MTT) assay for chemosensitivity testing in childhood leukemia

1988 • 154 citations

Syndecan-1 expression is up-regulated in pancreatic but not in other gastrointestinal cancers

2000 • 153 citations

Syndecan-1 (CD138) Immunoreactivity in Bone Marrow Biopsies of Multiple Myeloma: Shed Syndecan-1 Accumulates in Fibrotic Regions

2001 • 127 citations

The Role of Syndecan-1 in Malignancies

1996 • 114 citations

High levels of soluble syndecan-1 in myeloma-derived bone marrow: modulation of hepatocyte growth factor activity

2000 • 105 citations

Elevated levels of shed syndecan‐1 correlate with tumour mass and decreased matrix metalloproteinase‐9 activity in the serum of patients with multiple myeloma

1997 • 100 citations

Multiple Heparan Sulfate Chains Are Required for Optimal Syndecan-1 Function

1998 • 91 citations

Adhesion of B lymphoid (MPC-11) cells to type I collagen is mediated by integral membrane proteoglycan, syndecan.

1992 • 90 citations

Growth of human myeloid leukemias in the human marrow environment of SCID-hu mice

1993 • 89 citations

The Mi15 monoclonal antibody (anti-syndecan-1) is a reliable marker for quantifying plasma cells in paraffin-embedded bone marrow biopsy specimens

1999 • 87 citations

Suppression of tumor cell growth by syndecan-1 ectodomain.

1994 • 78 citations

Syndecan-1 Expression on Malignant Cells from the Blood and Marrow of Patients with Plasma Cell Proliferative Disorders and B-Cell Chronic Lymphocytic Leukemia

1998 • 70 citations

SYNDECANS: MULTIFUNCTIONAL CELLSURFACE CO-RECEPTOR

1997 • 3 citations