Developmental Pathways in Musculoskeletal Neoplasia: Involvement of the Indian Hedgehog-Parathyroid Hormone-Related Protein Pathway

Regulation of Rate of Cartilage Differentiation by Indian Hedgehog and PTH-Related Protein

1996 • 1,952 citations

Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation

1999 • 1,682 citations

PTH/PTHrP Receptor in Early Development and Indian Hedgehog—Regulated Bone Growth

1996 • 1,303 citations

A Parathyroid Hormone-Related Protein Implicated in Malignant Hypercalcemia: Cloning and Expression

1987 • 1,293 citations

Lethal skeletal dysplasia from targeted disruption of the parathyroid hormone-related peptide gene.

1994 • 1,138 citations

Teratogen-Mediated Inhibition of Target Tissue Response to Shh Signaling

1998 • 839 citations

Toward a molecular understanding of skeletal development

1995 • 683 citations

The natural history of hereditary multiple exostoses.

1994 • 593 citations

Tout-velu is a Drosophila homologue of the putative tumour suppressor EXT-1 and is needed for Hh diffusion

1998 • 505 citations

Parathyroid hormone-related peptide-depleted mice show abnormal epiphyseal cartilage development and altered endochondral bone formation.

1994 • 455 citations

The putative tumor suppressors EXT1 and EXT2 form a stable complex that accumulates in the Golgi apparatus and catalyzes the synthesis of heparan sulfate

2000 • 433 citations

Disruption of Gastrulation and Heparan Sulfate Biosynthesis in EXT1-Deficient Mice

2000 • 408 citations

Indian hedgehog couples chondrogenesis to osteogenesis in endochondral bone development

2001 • 396 citations

The malignant potential of enchondromatosis.

1987 • 328 citations

Benign and malignant cartilage tumors of bone and joint: their anatomic and theoretical basis with an emphasis on radiology, pathology and clinical biology. II. Juxtacortical cartilage tumors

1999 • 279 citations

Hereditary multiple exostosis.

2013 • 264 citations

A mutant PTH/PTHrP type I receptor in enchondromatosis

2002 • 255 citations

The parathyroid hormone/parathyroid hormone-related peptide receptor coordinates endochondral bone development by directly controlling chondrocyte differentiation

1998 • 254 citations

Benign and malignant cartilage tumors of bone and joint: their anatomic and theoretical basis with an emphasis on radiology, pathology and clinical biology

1997 • 229 citations

A gene for hereditary multiple exostoses maps to chromosome 19p

1994 • 211 citations

Genetic heterogeneity in families with hereditary multiple exostoses.

1993 • 197 citations

Hereditary multiple exostosis and chondrosarcoma: linkage to chromosome II and loss of heterozygosity for EXT-linked markers on chromosomes II and 8.

1995 • 194 citations

EXT-Mutation Analysis and Loss of Heterozygosity in Sporadic and Hereditary Osteochondromas and Secondary Chondrosarcomas

1999 • 186 citations

Teratogenic compounds of Veratrum californicum (Durand). V. Comparison of cyclopian effects of steroidal alkaloids from the plant and structurally related compounds from other sources

1968 • 153 citations

Identification and localization of the gene for EXTL, a third member of the multiple exostoses gene family.

1997 • 147 citations

The link between heparan sulfate and hereditary bone disease: finding a function for the EXT family of putative tumor suppressor proteins

2001 • 147 citations

The tricho-rhino-phalangeal syndrome(s): Chromosome 8 long arm deletion: Is there a shortest region of overlap between reported cases? TRP I and TRP II syndromes: Are they separate entities?

1984 • 85 citations

EXT genes are differentially expressed in bone and cartilage during mouse embryogenesis

2000 • 68 citations

Structure, Chromosomal Location, and Expression Profile of EXTR1 and EXTR2, New Members of the Multiple Exostoses Gene Family

1998 • 56 citations

Direct Inhibition of Indian Hedgehog Expression by Parathyroid Hormone (PTH)/PTH-Related Peptide and Up-Regulation by Retinoic Acid in Growth Plate Chondrocyte Cultures

2001 • 47 citations

A Clinical Guide to Primary Bone Tumors

1998 • 14 citations

Intraoperative Arthrography and the Ilizarov Technique

1997 • 6 citations

Regulators of normal development and tumor suppression.

1993 • 3 citations