Stable in vivo expression of the cystic fibrosis transmembrane conductance regulator with an adeno-associated virus vector.

Identification of the Cystic Fibrosis Gene: Cloning and Characterization of Complementary DNA

1989 • 7,327 citations

Therapy of CF-Patients with Amitriptyline and Placebo - a Randomised, Double-Blind, Placebo-Controlled Phase IIb Multicenter, Cohort-Study

2013 • 2,504 citations

In vivo transfer of the human cystic fibrosis transmembrane conductance regulator gene to the airway epithelium

1992 • 953 citations

Site-specific integration by adeno-associated virus.

1996 • 803 citations

Targeted integration of adeno-associated virus (AAV) into human chromosome 19.

1991 • 774 citations

Helper-free stocks of recombinant adeno-associated viruses: normal integration does not require viral gene expression

1989 • 741 citations

Characterization of a preferred site on human chromosome 19q for integration of adeno-associated virus DNA by non-homologous recombination.

1992 • 493 citations

Correction of the ion transport defect in cystic fibrosis transgenic mice by gene therapy

1993 • 439 citations

Defective regulation of outwardly rectifying Cl− channels by protein kinase A corrected by insertion of CFTR

1992 • 418 citations

Expression of the cystic fibrosis transmembrane conductance regulator from a novel adeno-associated virus promoter.

1993 • 337 citations

Mapping and direct visualization of a region-specific viral DNA integration site on chromosome 19q13-qter

1991 • 322 citations

A Cystic Fibrosis Bronchial Epithelial Cell Line: Immortalization by Adeno-12-SV40 Infection

1991 • 308 citations

Detection of human papillomavirus DNA in formalin-fixed tissues by in situ hybridization after amplification by polymerase chain reaction.

1991 • 195 citations

An improved technique for the in situ detection of DNA after polymerase chain reaction amplification.

1991 • 186 citations

A human parvovirus, adeno-associated virus, as a eucaryotic vector: transient expression and encapsidation of the procaryotic gene for chloramphenicol acetyltransferase.

1984 • 185 citations

EPIDEMIOLOGY OF ADENOVIRUS-ASSOCIATED VIRUS INFECTION IN A NURSERY POPULATION1

1968 • 172 citations

Gene Expression from Adeno-associated Virus Vectors in Airway Epithelial Cells

1992 • 165 citations

Adeno-associated virus vectors

1992 • 161 citations

A Human Parvovirus, Adeno-Associated Virus, as a Eucaryotic Vector: Transient Expression and Encapsidation of the Procaryotic Gene for Chloramphenicol Acetyltransferase

1984 • 67 citations

Reconstitution of tracheal grafts with a genetically modified epithelium.

1991 • 58 citations

Cystic Fibrosis Gene and Protein Expression during Fetal Lung Development

1993 • 57 citations