Real-time polymerase chain reaction of immunoglobulin rearrangements for quantitative evaluation of minimal residual disease in multiple myeloma

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1996 • 6,155 citations

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A PROSPECTIVE, RANDOMIZED TRIAL OF AUTOLOGOUS BONE MARROW TRANSPLANTATION AND CHEMOTHERAPY IN MULTIPLE MYELOMA

2013 • 2,176 citations

A novel method for real time quantitative RT-PCR.

1996 • 2,093 citations

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1989 • 602 citations

Simple and Rapid Preparation of Samples for PCR

1989 • 596 citations

Total Therapy With Tandem Transplants for Newly Diagnosed Multiple Myeloma

1999 • 499 citations

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1988 • 462 citations

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1998 • 345 citations

Real-time quantitative PCR for the detection of minimal residual disease in acute lymphoblastic leukemia using junctional region specific TaqMan probes

1998 • 339 citations

Outcome prediction in childhood acute lymphoblastic leukaemia by molecular quantification of residual disease at the end of induction

1994 • 276 citations

Transplantation of CD34+ peripheral blood progenitor cells after high- dose chemotherapy for patients with advanced multiple myeloma

1995 • 272 citations

Molecular and Clinical Remissions in Multiple Myeloma: Role of Autologous and Allogeneic Transplantation of Hematopoietic Cells

1999 • 253 citations

Quantitation of minimal residual disease in Philadelphia chromosome positive chronic myeloid leukaemia patients using real‐time quantitative RT‐PCR

1998 • 247 citations

Eradication of polymerase chain reaction-detectable chronic lymphocytic leukemia cells is associated with improved outcome after bone marrow transplantation

1996 • 225 citations

Multicenter phase III trial to evaluate CD34(+) selected versus unselected autologous peripheral blood progenitor cell transplantation in multiple myeloma.

1999 • 175 citations

Detection and quantitation of malignant cells in the peripheral blood of multiple myeloma patients

1992 • 174 citations

Detection of minimal residual disease in patients with AML1/ETO-associated acute myeloid leukemia using a novel quantitative reverse transcription polymerase chain reaction assay

1998 • 168 citations

Molecular Monitoring of Minimal Residual Disease in Follicular and Mantle Cell Non-Hodgkin's Lymphomas Treated With High-Dose Chemotherapy and Peripheral Blood Progenitor Cell Autografting

1997 • 166 citations

Failure of Immunologic Purging in Mantle Cell Lymphoma Assessed by Polymerase Chain Reaction Detection of Minimal Residual Disease

1997 • 157 citations

Purified CD34+ Lin- Thy+ stem cells do not contain clonal myeloma cells

1995 • 146 citations

High-dose sequential chemoradiotherapy in multiple myeloma: residual tumor cells are detectable in bone marrow and peripheral blood cell harvests and after autografting

1995 • 145 citations

Immunoglobulin heavy-chain consensus probes for real-time PCR quantification of residual disease in acute lymphoblastic leukemia

2000 • 144 citations

Analysis of B-lymphoid malignancies using allele-specific polymerase chain reaction: a technique for sequential quantitation of residual disease

1991 • 134 citations

Double-intensive therapy in high-risk multiple myeloma

1992 • 133 citations

Improved quantitation of minimal residual disease in multiple myeloma using real-time polymerase chain reaction and plasmid-DNA complementarity determining region III standards.

1998 • 123 citations

Novel 5′ Exonuclease-Based Real-Time PCR Assay for the Detection of t(14;18)(q32;q21) in Patients with Follicular Lymphoma

1998 • 123 citations

Monoclonal antibody-purged bone marrow transplantation therapy for multiple myeloma

1993 • 108 citations

Ig VH gene mutational patterns indicate different tumor cell status in human myeloma and monoclonal gammopathy of undetermined significance

1996 • 103 citations

A novel nested-PCR strategy for the detection of rearranged immunoglobulin heavy-chain genes in B cell tumors

1997 • 102 citations

Quantitative comparison of multiple myeloma tumor contamination in bone marrow harvest and leukapheresis autografts.

1996 • 90 citations

High-dose sequential chemoradiotherapy, a widely applicable regimen, confers survival benefit to patients with high-risk multiple myeloma.

1994 • 82 citations

VH gene usage is multiple myeloma: complete absence of the VH4.21 (VH4- 34) gene

1996 • 79 citations

Circulating clonal lymphocytes in myeloma constitute a minor subpopulation of B cells [see comments]

1996 • 76 citations

Minimal residual disease after bone marrow transplantation for multiple myeloma: evidence for cure in long-term survivors.

1993 • 73 citations

Circulating Blood B Cells in Multiple Myeloma: Analysis and Relationship to Circulating Clonal Cells and Clinical Parameters in a Cohort of Patients Entered on the Eastern Cooperative Oncology Group Phase III E9486 Clinical Trial

1997 • 65 citations

Circulating clonal lymphocytes in myeloma constitute a minor subpopulation of B cells [see comments]

1996 • 59 citations

A Rapid and Quantitative Assay to Estimate Gene Transfer into Retrovirally Transduced Hematopoietic Stem/Progenitor Cells Using a 96-Well Format PCR and Fluorescent Detection System Universal for MMLV-Based Proviruses

1996 • 41 citations

A quantitative PCR assay for the detection of low amounts of malignant cells in multiple myeloma

1997 • 37 citations

Leukapheresis products in multiple myeloma: lower tumor load after mobilization with cyclophosphamide plus granulocyte colony-stimulating factor (G-CSF) compared with G-CSF alone.

1998 • 31 citations

Recombinant interferon‐γ inhibits the in vitro proliferation of human myeloma cells

1994 • 29 citations

Concomitant Mobilization of Plasma Cells and Hematopoietic Progenitors into Peripheral Blood of Patients with Multiple Myeloma

1996 • 28 citations

Immunoglobulin V_H4 gene usage in B lymphoid leukaemias

1993 • 27 citations

IgH/TCR delta PCR oligonucleotide liquid hybridization, a fast and sensitive assay for monitoring minimal residual disease in childhood B-precursor ALL.

1995 • 12 citations

Hematopoietic growth factors stimulate paraprotein isotype production by bone marrow mononuclear cells in an aggressive case of multiple myeloma.

1995 • 1 citations