Detection of t(4;14)(p16.3;q32) Chromosomal Translocation in Multiple Myeloma by Double-Color Fluorescent In Situ Hybridization

A clinical staging system for multiple myeloma correlation of measured myeloma cell mass with presenting clinical features, response to treatment, and survival

1975 • 3,051 citations

Cancer: Principles and Practice of Oncology

1997 • 1,408 citations

High-Resolution Mapping of Human Chromosome 11 by in Situ Hybridization with Cosmid Clones

1990 • 1,357 citations

Structural and Functional Diversity in the FGf Receptor Multigene Family

1992 • 1,262 citations

The Fgf Family of Growth Factors and Oncogenes

1992 • 1,164 citations

Multiple Myeloma: Increasing Evidence for a Multistep Transformation Process

1998 • 761 citations

Frequent translocation t(4;14)(p16.3;q32.3) in multiple myeloma is associated with increased expression and activating mutations of fibroblast growth factor receptor 3

1997 • 657 citations

The t(4;14) Translocation in Myeloma Dysregulates Both FGFR3and a Novel Gene, MMSET, Resulting in IgH/MMSET Hybrid Transcripts

1998 • 555 citations

Promiscuous translocations into immunoglobulin heavy chain switch regions in multiple myeloma

1996 • 389 citations

Frequent Dysregulation of the c-maf Proto-Oncogene at 16q23 by Translocation to an Ig Locus in Multiple Myeloma

1998 • 388 citations

Deregulation of MUM1/IRF4 by chromosomal translocation in multiple myeloma

1997 • 351 citations

FGFR activation in skeletal disorders: Too much of a good thing

1997 • 319 citations

WHSC1, a 90 kb SET Domain-Containing Gene, Expressed in Early Development and Homologous to a Drosophila Dysmorphy Gene Maps in the Wolf-Hirschhorn Syndrome Critical Region and is Fused to IgH in t(1;14) Multiple Myeloma

1998 • 315 citations

Fibroblast-growth-factor receptor mutations in human skeletal disorders

1995 • 300 citations

Dysregulation of cyclin D1 by translocation into an IgH gamma switch region in two multiple myeloma cell lines [see comments]

1996 • 296 citations

Identification of a locus control region in the immunoglobulin heavy-chain locus that deregulates c-myc expression in plasmacytoma and Burkitt's lymphoma cells.

1994 • 258 citations

A Novel Chromosomal Translocation t(4; 14)(p16.3; q32) in Multiple Myeloma Involves the Fibroblast Growth-Factor Receptor 3 Gene

1997 • 216 citations

Multiple myeloma: high incidence of chromosomal aneuploidy as detected by interphase fluorescence in situ hybridization.

1995 • 206 citations

The Ig Heavy Chain Gene Is Frequently Involved in Chromosomal Translocations in Multiple Myeloma and Plasma Cell Leukemia as Detected by In Situ Hybridization

1997 • 198 citations

Cytogenetic analysis of 280 patients with multiple myeloma and related disorders: Primary breakpoints and clinical correlations

1997 • 167 citations

Characterization of Nonrandom Chromosomal Gains and Losses in Multiple Myeloma by Comparative Genomic Hybridization

1998 • 153 citations

Interphase fluorescence in situ hybridization identifies chromosomal abnormalities in plasma cells from patients with monoclonal gammopathy of undetermined significance

1995 • 143 citations

The application of fluorescent in situ hybridization to detect Mbcr/abl fusion in variant Ph chromosomes in CML and ALL

1993 • 118 citations

A gene encoding a fibroblast growth factor receptor isolated from the Huntington disease gene region of human chromosome 4

1991 • 117 citations

Expanded range of 11q13 breakpoints with differing patterns of cyclin D1 expression in B‐cell malignancies

1993 • 112 citations

A cosmid contig and high resolution restriction map of the 2 megabase region containing the Huntington's disease gene

1993 • 100 citations

Molecular Analysis of 11q13 Breakpoints in Multiple Myeloma

1999 • 86 citations

Neoplastic Diseases of the Blood

1996 • 85 citations

Interphase and metaphase detection of the breakpoint of 14q32 translocations in B-cell malignancies by double-color fluorescence in situ hybridization

1995 • 73 citations

Nonrandom chromosomal rearrangements of 14q32.3 and 19p13.3 and preferential deletion of 1p in 21 patients with multiple myeloma and plasma cell leukemia

1994 • 67 citations

Biclonal and hypodiploid multiple myeloma

1986 • 59 citations

FGFR3 Gene Mutations Associated With Human Skeletal Disorders Occur Rarely in Multiple Myeloma

1998 • 39 citations

Comparison of chromosome analysis and BCL‐1 rearrangement in a series of patients with multiple myeloma

1992 • 34 citations

Anomalous rearrangements of the immunoglobulin heavy chain genes in human leukemias support the loop-out mechanism of class switch.

1992 • 12 citations