Multiple RNA Polymerase Conformations and GreA: Control of the Fidelity of Transcription

Rapid and efficient site-specific mutagenesis without phenotypic selection.

1985 • 7,573 citations

Binding Energy, Specificity, and Enzymic Catalysis: The Circe Effect

1975 • 844 citations

FIDELITY MECHANISMS IN DNA REPLICATION

1991 • 709 citations

Analysis of numerical methods for computer simulation of kinetic processes: Development of KINSIM—A flexible, portable system

1983 • 597 citations

Pre-steady-state kinetic analysis of processive DNA replication including complete characterization of an exonuclease-deficient mutant

1991 • 495 citations

Transcript cleavage factors from E. coli

1993 • 368 citations

An induced-fit kinetic mechanism for DNA replication fidelity: direct measurement by single-turnover kinetics

1991 • 364 citations

Kinetic mechanism of DNA polymerase I (Klenow)

1987 • 352 citations

The RNA polymerase II ternary complex cleaves the nascent transcript in a 3'----5' direction in the presence of elongation factor SII.

1992 • 280 citations

Ribozyme-catalyzed and nonenzymic reactions of phosphate diesters: rate effects upon substitution of sulfur for a nonbridging phosphoryl oxygen atom

1991 • 230 citations

Kinetic mechanism of DNA polymerase I(Klenow fragment): identification of a second conformational change and evaluation of the internal equilibrium constant

1991 • 218 citations

Kinetic partitioning between the exonuclease and polymerase sites in DNA error correction

1991 • 208 citations

Kinetic characterization of the polymerase and exonuclease activities of the gene 43 protein of bacteriophage T4

1992 • 207 citations

Elongation factor-dependent transcript shortening by template-engaged RNA polymerase II.

1992 • 197 citations

Transcription : mechanisms and regulation

1994 • 195 citations

Structural analysis of ternary complexes of Escherichia coli RNA polymerase

1992 • 154 citations

[61] Rapid kinetic analysis of mechanochemical adenosinetriphosphatases

1986 • 151 citations

Spontaneous cleavage of RNA in ternary complexes of Escherichia coli RNA polymerase and its significance for the mechanism of transcription.

1991 • 149 citations

GreA protein: a transcription elongation factor from Escherichia coli.

1992 • 149 citations

Ribonucleic Acid Chain Elongation by Escherichia coli Ribonucleic Acid Polymerase

1974 • 129 citations

Mapping and characterization of transcriptional pause sites in the early genetic region of bacteriophage T7

1987 • 129 citations

Analysis of RNA Chain Elongation and Termination by Saccharomyces cerevisiae RNA Polymerase III

1994 • 113 citations

The Single-Nucleotide Addition Cycle in Transcription: a Biophysical and Biochemical Perspective

1992 • 105 citations

Identification of a 3'-->5' exonuclease activity associated with human RNA polymerase II.

1993 • 103 citations

Structure and function of the bacteriophage T4 DNA polymerase holoenzyme

1992 • 96 citations

Protein‐protein interactions at a DNA replication fork: bacteriophage T4 as a model

1992 • 93 citations

Processive proofreading is intrinsic to T4 DNA polymerase.

1992 • 87 citations

6 Chemical Basis of Biological Phosphoryl Transfer

1973 • 86 citations

Mechanism of DNA replication fidelity for three mutants of DNA polymerase I: Klenow fragment KF(exo+), KF(polA5), and KF(exo-)

1991 • 81 citations

RNA Polymerase Marching Backward

1993 • 74 citations