Decreased mucosal interleukin-4 (IL-4) production in gut inflammation.

Heterogeneity of Cytokine Secretion Patterns and Functions of Helper T Cells

1989 • 1,122 citations

IL-4 induces adherence of human eosinophils and basophils but not neutrophils to endothelium. Association with expression of VCAM-1.

1992 • 838 citations

Tumor necrosis factor α-producing cells in the intestinal mucosa of children with inflammatory bowel disease

1994 • 578 citations

Inhibition of leukotriene synthesis markedly accelerates healing in a rat model of inflammatory bowel disease

1989 • 433 citations

The mouse gut T lymphocyte, a novel type of T cell. Nature, origin, and traffic in mice in normal and graft-versus-host conditions.

1978 • 422 citations

Human B cell clones can be induced to proliferate and to switch to IgE and IgG4 synthesis by interleukin 4 and a signal provided by activated CD4+ T cell clones.

1991 • 333 citations

Interleukin-2- and interferon-gamma-secreting T cells in normal and diseased human intestinal mucosa.

1993 • 324 citations

Interleukin 4 induces synthesis of IgE and IgG4 in human B cells

1989 • 300 citations

Effects of tumor necrosis factor, lipopolysaccharide, and IL-4 on the expression of vascular cell adhesion molecule-1 in vivo. Correlation with CD3+ T cell infiltration.

1992 • 227 citations

Increased interleukin-2 messenger RNA in the intestinal mucosal lesions of Crohn's disease but not ulcerative colitis

1992 • 220 citations

Mucosal injury and inflammation in a model of chronic granulomatous colitis in rats

1993 • 181 citations

Synergistic effect of IL-4 and IFN-gamma on the expression of polymeric Ig receptor (secretory component) and IgA binding by human epithelial cells.

1990 • 177 citations

Spontaneous release of interferon gamma by intestinal lamina propria lymphocytes in Crohn's disease. Kinetics of in vitro response to interferon gamma inducers.

1991 • 171 citations

Lymphocytes isolated from the intestinal lamina propria of normal nonhuman primates have increased expression of genes associated with T-cell activation

1988 • 163 citations

Differential expression of CD25 (interleukin-2 receptor) on lamina propria T cells and macrophages in the intestinal lesions in Crohn's disease and ulcerative colitis.

1990 • 158 citations

Cytokine mRNA Expression in Intestine from Normal and Inflammatory Bowel Disease Patients

1993 • 80 citations

Plasma interleukin-2 and a soluble/shed interleukin-2 receptor in serum of patients with Crohn's disease. Effect of cyclosporin.

1990 • 78 citations

Terminally Differentiated Human Intestinal B Cells

1990 • 43 citations

Selective biopsy of human Peyer's patches during ileal endoscopy

1987 • 42 citations

Interleukin-2 activity of colonic lamina propria mononuclear cells in a rat model of experimental colitis

1993 • 17 citations