Mucosal injury and inflammation in a model of chronic granulomatous colitis in rats

Nitric oxide: physiology, pathophysiology, and pharmacology.

1991 • 15,563 citations

Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids

1982 • 11,668 citations

Cloning and Characterization of Inducible Nitric Oxide Synthase from Mouse Macrophages

1992 • 1,914 citations

Biosynthesis and Metabolism of Endothelium-Derived Nitric Oxide

1990 • 1,284 citations

Mammalian nitrate biosynthesis: mouse macrophages produce nitrite and nitrate in response to Escherichia coli lipopolysaccharide.

1985 • 1,146 citations

L-arginine is required for expression of the activated macrophage effector mechanism causing selective metabolic inhibition in target cells.

1987 • 958 citations

Arthritis in rats after systemic injection of streptococcal cells or cell walls.

1977 • 437 citations

Effect of exogenous and endogenous nitric oxide on mitochondrial respiration of rat hepatocytes

1991 • 395 citations

Nitric oxide production is required for murine resident peritoneal macrophages to suppress mitogen-stimulated T cell proliferation. Role of IFN-gamma in the induction of the nitric oxide-synthesizing pathway.

1991 • 384 citations

Resistance of germfree rats to indomethacin-induced intestinal lesions

1977 • 313 citations

[80] Assessment of leukocyte involvement during ischemia and reperfusion of intestine

1990 • 294 citations

Effects of polymorphonuclear leukocyte transmigration on the barrier function of cultured intestinal epithelial monolayers.

1987 • 289 citations

A comparative analysis of two models of colitis in rats

1992 • 265 citations

Activated macrophages kill pancreatic syngeneic islet cells via arginine-dependent nitric oxide generation

1991 • 257 citations

Mammalian nitrate biosynthesis: incorporation of 15NH3 into nitrate is enhanced by endotoxin treatment.

1983 • 211 citations

Pharmacological methods in the control of inflammation

1989 • 191 citations

Ethanol-induced injury to the rat gastric mucosa

1990 • 189 citations

Granulomatous enterocolitis induced in rats by purified bacterial cell wall fragments

1985 • 179 citations

Regional Intestinal Blood Flow in Ulcerative Colitis and Crohn's Disease

1977 • 161 citations

Escherichia coli antibodies in patients with inflammatory bowel disease.

1978 • 154 citations

Urinary nitrate excretion in relation to murine macrophage activation. Influence of dietary L-arginine and oral NG-monomethyl-L-arginine.

1991 • 146 citations

Activation of the alternate complement pathway by peptidoglycan from streptococcal cell wall

1978 • 129 citations

Metabolism of trinitrobenzene sulfonic acid by the rat colon produces reactive oxygen species

1991 • 128 citations

The Chemotactic Peptide N-Formyl Methionyl-Loucyl-Phenylalanine Increases Mucosal Permeability in the Distal Ileum of the Rat

1988 • 94 citations

Inhibition by cyclosporin A of streptococcal cell wall‐induced arthritis and hepatic granulomas in rats

1986 • 88 citations

Pathophysiology of gastrointestinal mucosal permeability

1990 • 82 citations

Bacterial cell wall-induced hepatic granulomas. An in vivo model of T cell-dependent fibrosis.

1986 • 82 citations

Selected Bacterial Antibodies in Crohn's Disease and Ulcerative Colitis

1983 • 72 citations

Nitrite from inflammatory cells—A cancer risk factor in ulcerative colitis?

1990 • 61 citations

Role of kallikrein-kinin system in pathogenesis of bacterial cell wall-induced inflammation

1991 • 61 citations

Immunomodulation by Bacteria and Their Products

1982 • 59 citations

Role of Intestinal Microflora in Initiation and Perpetuation of Inflammatory Bowel Disease

1990 • 51 citations

Quantitative Measurement of Regional Colon Blood Flow in the Normal and Pathological Human Bowel

1966 • 50 citations

Inhibitors of reactive oxygen intermediates suppress bacterial cell wall-induced arthritis.

1991 • 45 citations

Inflammatory bowel disease

1991 • 15 citations

Effects of Streptococcal Components on Immunity

1981 • 6 citations