Acetylcholine and cholecystokinin induce different patterns of oscillating calcium signals in pancreatic acinar cells

Cytoplasmic Ca2+ oscillations evoked by receptor stimulation, G-protein activation, internal application of inositol trisphosphate or Ca2+: simultaneous microfluorimetry and Ca2+ dependent Cl- current recording in single pancreatic acinar cells.

1990 • 291 citations

Two functionally distinct cholecystokinin receptors show different modes of action on Ca2+ mobilization and phospholipid hydrolysis in isolated rat pancreatic acini. Studies using a new cholecystokinin analog, JMV-180.

1990 • 166 citations

Oscillations of free cytosolic calcium evoked by cholinergic and catecholaminergic agonists in rat parotid acinar cells.

1988 • 147 citations

Oscillations of cytosolic calcium in single pancreatic acinar cells stimulated by acetylcholine

1988 • 132 citations

Oscillating intracellular Ca2+ signals evoked by activation of receptors linked to inositol lipid hydrolysis: Mechanism of generation

1990 • 121 citations

Oscillatory mode of calcium signaling in rat pancreatic acinar cells

1990 • 111 citations

Phorbol-ester-induced alterations of free calcium ion transients in single rat hepatocytes

1987 • 108 citations

Evidence for an inhibitory effect of protein kinase C on G-protein-mediated repetitive calcium transients in hamster eggs.

1989 • 103 citations

Acetylcholine and cholecystokinin receptors functionally couple by different G‐proteins to phospholipase C in pancreatic acinar cells

1988 • 62 citations

Structure-activity relationship studies on cholecystokinin: analogues with partial agonist activity

1988 • 62 citations

Cholecystokinin activates Gi1-, Gi2-, Gi3- and several Gs-proteins in rat pancreatic acinar cells

1990 • 57 citations

Isomers of inositol trisphosphate in exocrine pancreas

1986 • 55 citations

Protein kinase C activators inhibit the inositol trisphosphate‐mediated muscarinic current responses in rat lacrimal cells.

1987 • 53 citations

Measurement of cytosolic free Ca²⁺ in individual pancreatic acini

1988 • 47 citations

Substance P and bombesin elevate cytosolic Ca2+ by different molecular mechanisms in a rat pancreatic acinar cell line.

1990 • 44 citations

Activation and desensitization mechanisms of muscarinic current response in single pancreatic acinar cells of rats.

1989 • 40 citations

Receptor-activated cytoplasmic Ca2+ oscillations in pancreatic acinar cells: Generation and spreading of Ca2+ signals

1991 • 38 citations

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