Balanced mechanical forces and microtubule contribution to fibroblast contraction

Production of a tissue-like structure by contraction of collagen lattices by human fibroblasts of different proliferative potential in vitro.

1979 • 2,025 citations

Fibroblasts, myofibroblasts, and wound contraction

1994 • 1,150 citations

Cellular tensegrity: defining new rules of biological design that govern the cytoskeleton

1993 • 1,124 citations

Fibroblast traction as a mechanism for collagen morphogenesis

1981 • 862 citations

GRANULATION TISSUE AS A CONTRACTILE ORGAN

1972 • 802 citations

Viscoelastic properties of vimentin compared with other filamentous biopolymer networks.

1991 • 694 citations

Integrins as mechanochemical transducers

1991 • 684 citations

Isometric contraction by fibroblasts and endothelial cells in tissue culture: a quantitative study

1992 • 456 citations

Taxol binds to cellular microtubules.

1982 • 408 citations

Cytoplasmic filaments and gap junctions in epithelial cells and myofibroblasts during wound healing.

1978 • 328 citations

Fibroblast contractility and actin organization are stimulated by microtubule inhibitors

1989 • 303 citations

Tension and compression in the cytoskeleton of PC-12 neurites. II: Quantitative measurements.

1988 • 288 citations

β1 Integrin-mediated collagen gel contraction is stimulated by PDGF

1990 • 266 citations

Cell locomotion forces versus cell contraction forces for collagen lattice contraction: An in vitro model of wound contraction

1990 • 266 citations

Contraction due to microtubule disruption is associated with increased phosphorylation of myosin regulatory light chain.

1995 • 229 citations

Measurement of Mechanical Forces Generated by Skin Fibroblasts Embedded in a Three-Dimensional Collagen Gel

1991 • 227 citations

A culture force monitor for measurement of contraction forces generated in human dermal fibroblast cultures: evidence for cell-matrix mechanical signalling

1994 • 197 citations

Quantitative analysis of collagen gel contractile forces generated by dermal fibroblasts and the relationship to cell morphology

1996 • 196 citations

Analysis of the role of microfilaments and microtubules in acquisition of bipolarity and elongation of fibroblasts in hydrated collagen gels.

1984 • 177 citations

Effect of colcemid on fibroblast motility

1971 • 128 citations

Collagen gel contraction by fibroblasts requires cellular fibronectin but not plasma fibronectin

1991 • 78 citations

Changes in fibroblast contractility, morphology, and adhesion in response to a phorbol ester tumor promoter

1988 • 70 citations

Animal Cell Biotechnology

2007 • 65 citations

Contraction and the control of contraction

1980 • 65 citations

Opposing microtubule- and actin-dependent forces in the development and maintenance of structural polarity in retinal photoreceptors

1989 • 65 citations

Contrasting effects of maytansine and vinblastine on the alkylation of tubulin sulfhydryls

1981 • 51 citations

Colchicine and wound healing

1980 • 34 citations

Novel Method for Stereo Imaging in Light Microscopy at High Magnifications

1993 • 31 citations

Spatial orientation of microtubules in contractile fibroblasts in vivo

1978 • 19 citations