Stereoselective formation of benz[a]anthracene (+)-(5S,6R)-oxide and (+)-(8R,9S)-oxide by a highly purified and reconstituted system containing cytochrome P-450c

Hepatic Triphosphopyridine Nucleotide-Cytochrome c Reductase: Isolation, Characterization, and Kinetic Studies

1962 • 1,431 citations

Some properties of a detergent-solubilized NADPH-cytochrome c(cytochrome P-450) reductase purified by biospecific affinity chromatography.

1976 • 1,180 citations

Separation and characterization of highly purified forms of liver microsomal cytochrome P-450 from rats treated with polychlorinated biphenyls, phenobarbital, and 3-methylcholanthrene.

1979 • 576 citations

Regulation of three forms of cytochrome P-450 and epoxide hydrolase in rat liver microsomes. Effects of age, sex, and induction.

1981 • 304 citations

Hepatic microsomal cytochrome P-450 from rats treated with isosafrole. Purification and characterization of four enzymic forms.

1980 • 286 citations

Preparation of monospecific antibodies against two forms of rat liver cytochrome P-450 and quantitation of these antigens in microsomes

1979 • 180 citations

An enantiomeric interaction in the metabolism and tumorigenicity of (+)- and (-)-benzo[a]pyrene 7,8-oxide.

1980 • 86 citations

Arene Oxides-Oxepins

1973 • 74 citations

Stereochemical course in reactions between nucleophiles and arene oxides

1974 • 62 citations

The formation of dihydrodiols by the chemical or enzymic oxidation of benz[a]anthracene and 7,12-dimethylbenz[a]anthracene

1978 • 59 citations

Absolute stereochemistry of the trans-dihydrodiols formed from benzo[a]anthracene by liver microsomes

1979 • 47 citations

Enantioselectivity of microsomal epoxide hydrolase toward arene oxide substrates.

1981 • 45 citations

Metabolism of benzo[a]anthracene to its tumorigenic 3,4-dihydrodiol.

1979 • 41 citations

Stereoselectivity of rat liver cytochrome P-450c on formation of benzo[a]pyrene 4,5-oxide

1981 • 40 citations

Novel rearrangements during dehydration of nucleophile adducts of arene oxides. Reappraisal of premercapturic acid structures

1975 • 33 citations

Regiospecificity and stereospecificity in the enzymatic conjugation of glutathione with (±)-benzo(a)pyrene 4,5-oxide

1980 • 33 citations

Reactions of the K-region oxides of carcinogenic and related polycyclic hydrocarbons with nucleophiles: stereochemistry and regioselectivity

1976 • 26 citations

Glutathione S-conjugates of phenyloxirane

1981 • 17 citations

Carbon-13 nuclear magnetic resonance study of nucleophilic additions to benzo[a]pyrene-4,5-oxide and of its acid-catalyzed rearrangement

1979 • 14 citations

Metabolites of polycyclic aromatic hydrocarbons. II. Isomeric k-region phenols and methyl ethers of benz []anthracene

1975 • 11 citations

Synthesis and absolute stereochemistry of (+)- and (–)-benz[a]anthracene 8,9-oxide and derived mammalian liver metabolites of benz[a]-anthracene

1981 • 11 citations

Anthracene 1,2-oxide: synthesis and role in the metabolism of anthracene by mammals

1979 • 11 citations