Expression of MMPS, MT-MMP, and TIMPs in squamous cell carcinoma of the oral cavity: Correlations with tumor invasion and metastasis

A matrix metalloproteinase expressed on the surface of invasive tumour cells

1994 • 2,561 citations

Mechanism Of Cell Surface Activation Of 72-kDa Type IV Collagenase

1995 • 1,576 citations

Tumor invasion and the extracellular matrix.

1983 • 960 citations

Membrane Type 1 Matrix Metalloproteinase Digests Interstitial Collagens and Other Extracellular Matrix Macromolecules

1997 • 926 citations

Membrane-type matrix metalloproteinase (MT-MMP) gene is expressed in stromal cells of human colon, breast, and head and neck carcinomas.

1995 • 511 citations

Transmembrane/cytoplasmic domain-mediated membrane type 1-matrix metalloprotease docking to invadopodia is required for cell invasion

1997 • 419 citations

Differential expression of membrane-type matrix metalloproteinase and its correlation with gelatinase A activation in human malignant brain tumors in vivo and in vitro.

1996 • 278 citations

Expression of membrane-type matrix metalloproteinase in human gastric carcinomas

1995 • 267 citations

Activation of the precursor of gelatinase A/72 kda type IV collagenase/MMP‐2 in lung carcinomas correlates with the expression of membrane‐type matrix metalloproteinase (MT‐MMP) and with lymph node metastasis

1995 • 267 citations

Membrane-type matrix metalloproteinase 1 is a gelatinolytic enzyme and is secreted in a complex with tissue inhibitor of metalloproteinases 2.

1996 • 232 citations

High level of MT-MMP expression is associated with invasiveness of cervical cancer cells

1996 • 165 citations

Correlation of the in situ detection of polymerase chain reaction-amplified metalloproteinase complementary DNAs and their inhibitors with prognosis in cervical carcinoma.

1995 • 161 citations

Immunohistochemical localization of vascular endothelial growth factor in the human placenta

1996 • 136 citations

Possible contribution of active MMP2 to lymph-node metastasis and secreted cathepsin L to bone invasion of newly established human oral-squamous-cancer cell lines

1997 • 134 citations

Expression of Matrix Metalloproteinase-2 Related to Lymph Node Metastasis of Oral Squamous Cell Carcinoma: A Clinicopathologic Study

1993 • 131 citations

Expression of membrane-type matrix metalloproteinase 1 (MT1-MMP) in tumor cells enhances pulmonary metastasis in an experimental metastasis assay.

1996 • 121 citations

Increased expression of membrane type 1-matrix metalloproteinase in head and neck carcinoma

1997 • 121 citations

MT-MMP expression and localisation in human lung and breast cancers

1996 • 112 citations

Analysis of Expression of Matrix Metalloproteinases-2 and −9 in Hypopharyngeal Squamous Cell Carcinoma by in Situ Hybridization

1995 • 82 citations

Cytosol estrogen and progestin receptors in endometrial carcinoma of patients treated with surgery, radiotherapy, and progestin. Clinical correlates

1982 • 82 citations

Expression of matrix metalloproteinase-3 in stage I and II squamous cell carcinoma of the oral cavity

1995 • 81 citations

Expression of Matrix Metalloproteinases and Tissue Inhibitor of Metalloproteinases in Head and Neck Squamous Cell Carcinoma

1997 • 80 citations

An immunohistochemical study of the extracellular matrix in oral squamous cell carcinoma and its association with invasive and metastatic potential

1994 • 78 citations

Membrane-type matrix metalloproteinase expression and matrix metalloproteinase-2 activation in primary human ovarian epithelial carcinoma cells.

1996 • 73 citations

Production of matrix metalloproteinase 9 (92-kDa gelatinase) by human oesophageal squamous cell carcinoma in response to epidermal growth factor

1993 • 73 citations

Membrane-type matrix metal ioproteinase-1 expression at the site ofhuman placentation

1996 • 71 citations

The significance of epidermal growth factor receptor and matrix metalloproteinase-3 in squamous cell carcinoma of the oral cavity

1996 • 70 citations

Cellular activation of mesangial gelatinase A by cytochalasin D is accompanied by enhanced mRNA expression of both gelatinase A and its membrane-associated gelatinase A activator (MT-MMP)

1996 • 63 citations

Distribution of basement membrane in squamous cell carcinoma of the head and neck

1987 • 57 citations

Immunohistochemical localization of basement membrane type IV collagen in invasive and metastatic squamous carcinomas of the head and neck

1985 • 56 citations

Matrix-degrading metalloproteinases in tumor progression.

1994 • 54 citations

Princess Takamatsu symposia

1971 • 45 citations

Gelatinase A (MMP-2) and Its mRNA Detected in Both Neoplastic and Stromal Cells of Tumors with Different Invasive and Metastatic Properties

1994 • 42 citations

Expression of Type IV Collagen and Its Degrading Enzymes in Squamous Cell Carcinoma of Lung

1994 • 41 citations

Immunohistologic distribution of basement membrane in oral squamous cell carcinoma

1994 • 32 citations

Immunohistochemical Alterations in Basement Membrane Components of Squamous Cell Carcinoma

1991 • 28 citations

The 72-kDa Metalloproteinase Immunostaining in Cervical Carcinoma: Relationship with Lymph Nodal Involvement

1996 • 24 citations

Mode of tumor invasion in oral squamous cell carcinoma: Improved grading based on immunohistochemical examination of extracellular matrices

1996 • 22 citations