The CD4-Mediated Immune Response Is Critical in Determining the Outcome of Infection Using Theiler's Viruses with VP1 Capsid Protein Point Mutations

The interferon system. A bird's eye view of its biochemistry.

1992 • 633 citations

Immune Defence in Mice Lacking Type I and/or Type II Interferon Receptors

1995 • 296 citations

Persistent infection of oligodendrocytes in Theiler's virus-induced encephalomyelitis

1983 • 243 citations

Theiler's Virus-Induced Demyelination: Prevention by Immunosuppression

1976 • 242 citations

Theiler's murine encephalomyelitis virus (TMEV)-induced demyelinating disease in mice is influenced by the H-2D region: correlation with TEMV-specific delayed-type hypersensitivity.

1985 • 207 citations

Absence of neurological deficits following extensive demyelination in a class I-deficient murine model of multiple sclerosis

1998 • 198 citations

Susceptibility to Theiler's virus-induced demyelination. Mapping of the gene within the H-2D region.

1986 • 187 citations

Theiler's virus infection of 129Sv mice that lack the interferon alpha/beta or interferon gamma receptors.

1995 • 179 citations

CD4⁺and CD8⁺T Cells Make Discrete Contributions to Demyelination and Neurologic Disease in a Viral Model of Multiple Sclerosis

1998 • 117 citations

Class II major histocompatibility complex‐restricted T cell function in CD4‐deficient mice

1994 • 102 citations

The role of CD4 and CD8 T cells in viral infections

1991 • 84 citations

Role of natural killer cells as immune effectors in encephalitis and demyelination induced by Theiler's virus.

1989 • 82 citations

Three-dimensional structure of Theiler murine encephalomyelitis virus (BeAn strain).

1992 • 74 citations

Theiler's virus persistence and demyelination in major histocompatibility complex class II-deficient mice

1996 • 68 citations

Direct evidence of a role for amino acid 101 of VP-1 in central nervous system disease in Theiler's murine encephalomyelitis virus infection

1991 • 55 citations

Adaptation of Theiler's Virus to L929 Cells: Mutations in the Putative Receptor Binding Site on the Capsid Map to Neutralization Sites and Modulate Viral Persistence

1998 • 49 citations

Erichrome Stain for Myelin on Osmicated Tissue Embedded in Glycol Methacrylate Plastic

1989 • 42 citations

Adoptively transferred CD8+ T lymphocytes provide protection against TMEV-induced demyelinating disease in BALB/c mice.

1996 • 40 citations

Interferon alpha/beta mediates early virus-induced expression of H-2D and H-2K in the central nervous system.

1997 • 40 citations

Differential generation of class I H‐2D‐ versus H‐2K‐restricted cytotoxicity against a demyelinating virus following central nervous system infection

1997 • 36 citations

A Neutralization Site of DA Strain of Theiler's Murine Encephalomyelitis Virus Important for Disease Phenotype

1996 • 34 citations

A Theiler’s Virus Alternatively Initiated Protein Inhibits the Generation of H-2K-Restricted Virus-Specific Cytotoxicity

1999 • 29 citations

Role of T cells in resistance to Theiler's virus infection

1991 • 28 citations

Persistent infection of a glioma cell line generates a Theiler's virus variant which fails to induce demyelinating disease in SJL/J mice

1990 • 25 citations

Importance of amino acid 101 within capsid protein VP1 for modulation of Theiler's virus-induced disease

1994 • 24 citations

Protection of SJL/J mice from demyelinating disease mediated by Theiler's murine encephalomyelitis virus

1995 • 21 citations

Molecular Characterization of a Nondemyelinating Variant of Daniel’s Strain of Theiler’s Virus Isolated from a Persistently Infected Glioma Cell Line

1998 • 16 citations

Protection of SJL/J mice from demyelinating disease mediated by Theiler's murine encephalomyelitis virus

1995 • 4 citations