Great lakes embryo mortality, edema, and deformities syndrome (GLEMEDS) in colonial fish‐eating birds: Similarity to chick‐edema disease

2,3,7,8-Tetrachlorodibenzo-p-Dioxin and Related Halogenated Aromatic Hydrocarbons: Examination of the Mechanism of Toxicity

1982 • 2,512 citations

Official Methods of Analysis of the Association of Official Agricultural Chemists.

1951 • 1,578 citations

Polychlorinated Biphenyls (PCBs) and Polybrominated Biphenyls (PBBs): Biochemistry, Toxicology, and Mechanism of Action

1984 • 793 citations

The Logic of Scientific Discovery

1960 • 681 citations

Halogenated Biphenyls, Terphenyls, Naphthalenes, Dibenzodioxins and Related Products

1989 • 573 citations

Congenital Poisoning by Polychlorinated Biphenyls and Their Contaminants in Taiwan

1988 • 541 citations

Toxicology of chlorinated dibenzo-p-dioxins.

1973 • 478 citations

Prenatal exposure to polychlorinated biphenyls: Effects on birth size and gestational age

1984 • 449 citations

Handbook of Teratology

1977 • 427 citations

Microcontaminants and reproductive impairment of the Forster's tern on Green Bay, Lake Michigan-1983

1989 • 410 citations

Estrogenic activity of DDT analogs and polychlorinated biphenyls

1970 • 357 citations

Highly toxic coplanar PCBs: Occurrence, source, persistency and toxic implications to wildlife and humans

1987 • 347 citations

STUDIES ON THE MECHANISM OF ACTION OF THE CHLORINATED DIBENZO‐p‐DIOXINS AND RELATED COMPOUNDS*

1979 • 336 citations

Chlorinated Biphenyls in Fish, Mussels and Birds from the River Rhine and the Netherlands Coastal Area

1969 • 302 citations

Environmental fate of combustion-generated polychlorinated dioxins and furans

1984 • 271 citations

Identification and toxicological evaluation of chlorinated dibenzofuran and chlorinated naphthalene in two commercial polychlorinated biphenyls

1970 • 269 citations

Binding of a metabolite of 3,4,3′,4′-tetrachlorobiphenyl to transthyretin reduces serum vitamin A transport by inhibiting the formation of the protein complex carrying both retinol and thyroxin

1986 • 260 citations

Toxic contaminants in the Great Lakes 1984

1985 • 260 citations

Peregrine Falcon Populations: Their Biology and Decline.

1969 • 233 citations

Official methods of analysis of the association of official agricultural chemists

1966 • 222 citations

Physical behavior of PCBs in the Great Lakes

1983 • 216 citations

The injection of chemicals into the yolk sac of fertile eggs prior to incubation as a toxicity test

1963 • 209 citations

Polychlorinated biphenyl residues and egg mortality in double‐crested cormorants from the great lakes

1992 • 206 citations

Determination of 2,3,7,8-TCDD toxic equivalent factors (TEFs): support for the use of the in vitro AHH induction assay

1987 • 197 citations

Identification of chlorinated dibenzofurans in American polychlorinated biphenyls

1975 • 190 citations

Comparative toxicologic study with polychlorinated biphenyls in chickens with special reference to porphyria, edema formation, liver necrosis, and tissue residues

1970 • 184 citations

Toxic contaminants and ecosystem health: A great lakes focus

1989 • 184 citations

PCB isomers and congeners: Induction of aryl hydrocarbon hydroxylase and ethoxyresorufin O-deethylase enzyme activities in rat hepatoma cells

1982 • 184 citations

Chemical and Toxicological Evaluations of Isolated and Synthetic Chloro Derivatives of Dibenzo-p-dioxin

1968 • 183 citations

Prenatal exposure to environmental toxin: A test of the multiple effects model.

1984 • 182 citations

Biological Half-lives of Polychlorinated Biphenyl (PCB) Congeners in Whole Fish and Muscle of Rainbow Trout (Salmo gairdneri)

1983 • 169 citations

Distribution, redistribution, and geochronology of polychlorinated biphenyl congeners and other chlorinated hydrocarbons in Lake Ontario sediments

1989 • 157 citations

Behavioral Abnormalities of Nesting Lake Ontario Herring Gulls

1978 • 154 citations

Mechanism of action and structure-activity relationships for the chlorinated dibenzo-p-dioxins and related compounds

1989 • 154 citations

Toxicological assessment of hexachlorobiphenyl isomers and 2,3,7,8-tetrachlorodibenzofuran in chicks

1976 • 153 citations

Toxicity and 7-ethoxyresorufin O-deethylase-inducing potency of coplanar polychlorinated biphenyls (PCBs) in chick embryos

1988 • 145 citations

Quantitative characterization of polychlorinated biphenyl mixtures (aroclors® 1248, 1254 and 1260) by gas chromatograpy using capillary columns

1981 • 135 citations

Embryotoxicity, teratogenicity, and aryl hydrocarbon hydroxylase activity in forster's terns on green bay, lake michigan

1987 • 135 citations

Structurally specific binding of halogenated biphenyls to thyroxine transport protein

1986 • 135 citations

Reproduction in a Population of Herring Gulls (Larus argentatus) Contaminated by DDT

1966 • 134 citations

Peregrine Falcon Populations

1969 • 134 citations

Chronic toxicity, uptake, and retention of aroclor® 1254 in two estuarine fishes

1971 • 133 citations

Selenium teratogenesis in natural populations of aquatic birds in Central California

1988 • 127 citations

Patterns of PCDD, PCDF, and PCB contamination in Great Lakes fish and birds and their characterization by principal components analysis

1985 • 125 citations

Distribution of polychlorinated biphenyl congeners and other halocarbons in whole fish and muscle among Lake Ontario salmonids

1989 • 118 citations

H4IIE rat hepatoma cell bioassay-derived 2,3,7,8-tetrachlorodibenzo-p-dioxin equivalents in colonial fish-eating waterbird eggs from the Great Lakes

1991 • 115 citations

Etiology of chick edema disease.

1973 • 113 citations

Induction of Enzyme Activity in Cell Culture: A Rapid Screen for Detection of Planar Poly chlorinated Organic Compounds

1979 • 112 citations

A QUANTITATIVE ASSESSMENT OF THYROID HISTOPATHOLOGY OF HERRING GULLS (LARUS ARGENTATUS) FROM THE GREAT LAKES AND A HYPOTHESIS ON THE CAUSAL ROLE OF ENVIRONMENTAL CONTAMINANTS

1986 • 112 citations

Environmental contaminants and reproductive success of great blue herons Ardea herodias in British Columbia, 1986–1987

1989 • 111 citations

Pollutant-associated embryonic mortality of great lakes herring gulls

1977 • 110 citations

Comparison of the compositions of aroclor 1242 and aroclor 1016

1979 • 106 citations

Effect of a Polychlorinated Biphenyl on the Reproduction of Artificially and Naturally Incubated Dove Eggs

1973 • 105 citations

Pollutant Concentrations in Abnormal Young Terns from Long Island Sound

1972 • 105 citations

THE STRUCTURE-ACTIVITY RELATIONSHIPS OF HALOGENATED BIPHENYLS AS ENZYME INDUCERS

1979 • 104 citations

Physicochemical properties controlling polychlorinated biphenyl (PCB) concentrations in aquatic organisms

1984 • 104 citations

Sensitivity of Embryos from Duck, Goose, Herring Gull, and Various Chicken Breeds to 3,3′,4,4′-Tetrachlorobiphenyl

1988 • 103 citations

Reproductive Outcomes in Colonial Fish-Eating Birds: A Biomarker for Developmental Toxicants in Great Lakes Food Chains

1991 • 101 citations

Toxic potential of non-ortho and mono-ortho coplanar PCBs in commercial PCB preparations: “2,3,7,8-T4 CDD toxicity equivalence factors approach”

1988 • 99 citations

THE LOGIC OF SIR KARL POPPER AND THE PRACTICE OF EPIDEMIOLOGY

1986 • 95 citations

Association between PCBs and lower embryonic weight in black‐crowned night herons in San Francisco bay

1986 • 92 citations

Double-crested Cormorants of the Great Lakes: egg-laying parameters, reproductive failure, and contaminant residues in eggs, Lake Huron 1972–1973

1983 • 91 citations

ABNORMAL CHICKS AND PCB RESIDUE LEVELS IN EGGS OF COLONIAL BIRDS ON THE LOWER GREAT LAKES (1971-73)

1976 • 91 citations

History of Lake Ontario Contamination from the Niagara River by Sediment Radiodating and Chlorinated Hydrocarbon Analysis

1983 • 89 citations

Porphyria in herring gulls: A biochemical response to chemical contamination of great lakes food chains

1988 • 89 citations

Wildlife monitoring, modeling, and fugacity. Indicators of chemical contamination

1988 • 87 citations

Etiology of chick edema disease in Herring Gulls in the lower Great Lakes

1983 • 86 citations

An Exploration of Pesticides in a Lake Michigan Ecosystem

1966 • 85 citations

Eggshell thinning, chlorinated hydrocarbons, and mercury in inland aquatic bird eggs, 1969 and 1970.

1973 • 84 citations

Ecological significance of behavioral and hormonal abnormalities in breeding ring doves fed an organochlorine chemical mixture

1983 • 84 citations

Toxic contaminants and ecosystem health — A Great Lakes focus

1989 • 84 citations

Coplanar Polychlorinated Biphenyls in Aroclor and Kanechlor Mixtures

1987 • 82 citations

The identification and crystal structure of a hydropericardium-producing factor: 1,2,3,7,8,9-hexachlorodibenzo-p-dioxin

1969 • 79 citations

Studies of the Chick Edema Disease

1965 • 77 citations

Are polychlorinated biphenyl residues adequately described by Aroclor mixture equivalents? Isomer-specific principal components analysis of such residues in fish and turtles

1987 • 76 citations

Embryotoxic and teratogenic effects in unhatched fertile eggs from hens fed polychlorinated biphenyls (PCBs)

1974 • 76 citations

Cardiovascular teratogenicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin in the chick embryo

1981 • 75 citations

Molecular interactions of toxic chlorinated dibenzo-p-dioxins and dibenzofurans with thyroxine binding prealbumin

1985 • 74 citations

Mono-ortho-chlorinated chlorobiphenyls: Toxicity and induction of 7-ethoxyresorufinO-deethylase (EROD) activity in chick embryos

1990 • 74 citations

Differences in sensitivity of some avian species to the embryotoxicity of a PCB, 3,3′,4,4′-tetrachlorobiphenyl, injected into the eggs

1986 • 73 citations

Dioxin contamination and growth and development in great blue heron embryos

1991 • 73 citations

Comparison of polychlorinated dibenzodioxin levels with hepatic mixed‐function oxidase induction in great blue herons

1990 • 73 citations

Physiological implications of estrogen receptor modulation by 2,3,7,8-tetrachlorodibenzo-p-dioxin

1988 • 72 citations

Toxicity and persistence of PCB homologs and isomers in the avian system

1974 • 70 citations

Hydropericardium and Ascites in Chicks Fed a Chlorinated Hydrocarbon

1962 • 69 citations

PCB levels in egg yolks associated with embryonic mortality and deformity of hatched chicks

1973 • 65 citations

Determination, fate, and potential significance of PCBs in fish and sediment samples with emphasis on selected AHH-inducing congeners

1988 • 63 citations

Pollutants in breeding Herring Gulls in the lower Great Lakes

1974 • 62 citations

Embryonic Mortality and Chromosomal Alterations Caused by Aroclor 1254 in Ring Doves

1972 • 60 citations

Avian Thyroid: Effect of p , p ′-DDT on Size and Activity

1969 • 59 citations

Aroclor 1254� residues in birds: Lethal levels and loss rates

1984 • 58 citations

Studies on the mechanism of toxicity of the chlorinated dibenzo-p-dioxins.

1973 • 57 citations

Recent Changes in the Ring-Billed Gull Population and Biology in the Laurentian Great Lakes

1974 • 57 citations

Toxicology of Chlorinated Dibenzo-p-Dioxins

1973 • 57 citations

Species Differences in Experimental Porphyria Caused by Polyhalogenated Aromatic Compounds

1973 • 51 citations

Biochemical and Physiological Approaches in Ecotoxicology

1990 • 49 citations

The search for chlorinated dibenzofurans and chlorinated dibenzodioxins in wildlife populations showing elevated levels of embryonic death.

1973 • 49 citations

Toxicity Studies on Polychlorinated Biphenyls in the Chick

1971 • 49 citations

Alimentary toxemia in chickens.

1958 • 49 citations

A disorder of chickens probably due to a toxic feed; preliminary report.

1958 • 49 citations

Effects of Purified Polychlorinated Biphenyl Analogs on Chicken Reproduction

1975 • 49 citations

Aryl hydrocarbon hydroxylase levels in herring gull embryos from different locations on the great lakes

1985 • 48 citations

Polychlorinated biphenyl-induced decrease in liver vitamin A in Japanese quail and rats

1973 • 47 citations

Contaminant levels in colonial waterbirds from Green Bay and Lake Michigan, 1975?80

1985 • 47 citations

Yolk retinoids (vitamin a) in eggs of the herring gull and correlations with polychlorinated dibenzo‐p‐dioxins and dibenzofurans

1990 • 47 citations

Effects of Dietary Aroclor^® 1242 on Channel Catfish (Ictalurus punctatus) and the Selective Accumulation of PCB Components

1976 • 45 citations

Liver retinoid concentrations in natural populations of herring gulls (Larus argentatus) contaminated by 2,3,7,8-tetrachlorodibenzo-p-dioxin and in ring doves (Streptopelia risoria) injected with a dioxin analogue

1986 • 45 citations

Effects of Polychlorinated Biphenyls on Pheasant Reproduction, Behavior, and Survival

1971 • 45 citations

Investigation of the hepatic mixed‐function oxidase system in herring gull embryos in relation to environmental contaminants

1986 • 44 citations

Great Lakes Caspian Terns: Egg Contaminants and Biological Implications

1985 • 42 citations

The effects of polychlorinated biphenyls (Aroclor 1254) on chicken egg production, fertility and hatchability.

1973 • 41 citations

Polychlorinated Biphenyls: Their Effects on Penned Pheasants

1972 • 40 citations

The plight of the American bald eagle

1958 • 40 citations

Embryotoxic effects of three PCB's in the chicken

1973 • 38 citations

Dove reproduction and retinoid (vitamin A) dynamics in adult females and their eggs following exposure to 3,3′,4,4′-tetrachlorobiphenyl

1989 • 37 citations

Horizontal and Vertical Distribution of PCBs in Southern Lake Michigan Sediments and the Effect of Waukegan Harbor as a Point Source

1988 • 36 citations

Processes in pathology and microbiology

1985 • 36 citations

The Peregrine situation in Great Britain 1965–66

1967 • 36 citations

Seasonal changes in organochlorine compounds and mercury in common terns of Hamilton Harbour, Ontario

1974 • 35 citations

Biological half‐lives of chlorinated dibenzo‐p‐dioxins and dibenzofurans in rainbow trout (Salmo gairdneri)

1986 • 35 citations

Fate of hazardous waste derived organic compounds in Lake Ontario

1986 • 33 citations

Altered Electrolyte and Fluid Balance

1977 • 33 citations

Thyroid-vitamin a interactions in chicks exposed to 3,4,3′,4′-tetrachlorobiphenyl: Influence of low dietary vitamin a and iodine

1986 • 33 citations

Organochlorine Insecticides and PCB in Surficial Sediments of Lake Michigan (1975)

1981 • 32 citations

Influence of Polychlorinated Biphenyls in the Laying Hen

1973 • 32 citations

Highly carboxylated porphyrins as a biomarker of polyhalogenated aromatic hydrocarbon exposure in wildlife: Confirmation of their presence in Great Lakes Herring Gull chicks in the early 1970s and important methodological details

1990 • 32 citations

Mechanisms of teratogenesis*

1976 • 32 citations

Elimination of chlorinated dibenzofurans associated with polychoorinated biphenyls fed to mallards (Anas platyrhynchos)

1976 • 32 citations

THE ROLE OF "TOXIC FAT" IN THE PRODUCTION OF HYDROPERICARDIUM AND ASCITES IN CHICKENS.

1964 • 31 citations

Absorption Efficiency and Biological Half-life of Individual Chlorobiphenyls in Carp (Cyprinus carpio) Orally Exposed to Kanechlor Products

1982 • 31 citations

Toxicity Studies on Polychlorinated Biphenyls in the Chick

1972 • 31 citations

Studies of the Chick Edema Disease

1965 • 31 citations

Topics in environmental health

1983 • 30 citations

Low dietary iodine and thyroid anomalies in ring doves,Streptopelia risoria, Exposed to 3,4,3?,4?-Tetrachlorobiphenyl

1985 • 29 citations

Increased numbers and productivity of Double-crested Cormorants, Phalacrocorax auritus, on Lake Ontario

1986 • 29 citations

Biological Effects of Polychlorinated Biphenyls in Rats and Quail

1972 • 29 citations

Aroclor 1242 and reproductive success of adult mallards (Anas platyrhynchos)

1980 • 28 citations

Screening of Fresh Water Fish Extracts for Enzyme-Inducing Substances by an Aryl Hydrocarbon Hydroxylase Induction Bioassay Technique

1983 • 27 citations

Absorption efficiency and biological half-life of individual chlorobiphenyls in carp (Cyprinus carpio) orally exposed to Kanechlor products.

1982 • 27 citations

The permanent effects of early stilbestrol injections on the sex organs of the herring gull (Larus Argentatus)

1947 • 27 citations

Reproductive Success of Herring Gulls as an Indicator of Great Lakes Water Quality

1980 • 26 citations

The toxicopathology of Prudhoe Bay crude oil in chicken embryos

1990 • 26 citations

Early embryonic mortality in a Herring Gull colony in Lake Ontario

1974 • 24 citations

Electron microscopic alterations in the liver of chickens fed toxic fat.

1966 • 24 citations

Studies of the Chick Edema Disease

1963 • 24 citations

Carbon–Foam Chromatographic Separation of Non-o,o´-Chlorine Substituted PCBs from Aroclor Mixtures

1980 • 23 citations

Partitioning behavior of polychlorinated biphenyls

1985 • 23 citations

Organochlorine insecticides and PCB in the sediments of Lake Huron (1969) and Georgian Bay and North Channel (1973)

1979 • 23 citations

Review Lecture - Prealbumin and the thyroid hormone nuclear receptor

1981 • 22 citations

Teratogenic effects of benzo[a]pyrene in developing chick embryo

1988 • 19 citations

Polychlorinated Biphenyls Influence on Hatchability ,

1973 • 18 citations

Mutagenicity studies on herring gulls from different locations on the great lakes. i. sister chromatid exchange rates in herring‐gull embryos

1983 • 17 citations

The effects of receptor antagonists on the AHH induction activity of 2,3,7,8-TCDD in C57BL/6 and DBA/2 mice: 1,3,6,8-tetrachlorodibenzofuran

1987 • 16 citations

Toxicological Investigations of Pollutant-Related Effects in Great Lakes Gulls

1987 • 14 citations

Seasonal Distribution and Site Fidelity in Great Lakes Caspian Terns

1988 • 14 citations

Toxicity of polychlorinated biphenyls in poultry.

1972 • 14 citations

Developmental changes in vitamin A level and lack of retinyl palmitate in chick lungs

1990 • 13 citations

Hydropericardium Assay and Safety of Fats and Fatty Acid Products

1962 • 13 citations

Sequential study of the pathology of prudhoe bay crude oil in chicken embryos

1990 • 13 citations

Distribution of Chick Edema Factors in Chick Tissues

1971 • 12 citations

Proposed source of chick edema factor.

1972 • 11 citations

Etiology of Chick Edema Disease

1973 • 11 citations

Studies on the Mechanism of Toxicity of the Chlorinated Dibenzo-p-Dioxins

1973 • 10 citations

Some Physiological Responses of Broad Breasted Bronze Poults to Chlorinated Naphthalene

1958 • 10 citations

Polychlorinated Biphenyls: Their Effects on Penned Pheasants

1972 • 10 citations

Multifunctional Receptor Model for Dioxin and Related Compound Toxic Action: Possible Thyroid Hormone-Responsive Effector-Linked Site

1989 • 10 citations

Recent Fluctuations of Chlorobiphenyls (PCBs) in the Green Bay, Wisconsin, Region

1972 • 10 citations

Poisoning due to an oily by-product of rice-bran similar to chick edema disease. II. Tetrachlorodiphenyl as toxic substance.

1969 • 9 citations

The Search for Chlorinated Dibenzofurans and Chlorinated Dibenzodioxins in Wildlife Populations Showing Elevated Levels of Embryonic Death

1973 • 9 citations

Embryonic Mortality and Chromosomal Alterations Caused by Aroclor 1254 in Ring Doves

1972 • 8 citations

Biological Effects of Polychlorinated Biphenyls in Rats and Quail

1972 • 8 citations

Toxic potential of non-ortho and mono-ortho coplanar PCBs in commertial PCB preparations: '2,3,7,8-T4CDD toxicity equivalence factors approach'

1988 • 6 citations

Studies of the Chick Edema Disease

1968 • 4 citations

Recent Fluctuations of Chlorobiphenyls (PCBs) in the Green Bay, Wisconsin, Region

1972 • 3 citations

Response of Chicks and Turkey Poults to Aroclor 1242

1976 • 2 citations

Raising healthy pups.

1958 • 1 citations