The Relationship between Radiosensitivity and Repair of Potentially Lethal Damage in Human Tumor Cell Lines with Implications for Radioresponsiveness

The Analysis of Variance

1960 • 5,685 citations

BMDP Statistical Software 1981.

1984 • 5,347 citations

Inherent cellular radiosensitivity as a basic concept for human tumor radiotherapy

1981 • 530 citations

Intrinsic radiosensitivity of human cell lines is correlated with radioresponsiveness of human tumors: Analysis of 101 published survival curves

1985 • 488 citations

An ‘Incomplete-repair’ Model for Survival after Fractionated and Continuous Irradiations

1985 • 471 citations

Lethal and Potentially Lethal Lesions Induced by Radiation --- A Unified Repair Model

1986 • 469 citations

Repair of Potentially Lethal Damage in X-Irradiated HeLa Cells¹

2012 • 407 citations

Mean Inactivation Dose: A Useful Concept for Intercomparison of Human Cell Survival Curves

2012 • 361 citations

Plateau-phase cultures of mammalian cells: an in vitro model for human cancer.

1972 • 226 citations

Repair of Sub-lethal and Potentially Lethal Radiation Damage in Plateau Phase Cultures of Human Cells

1969 • 212 citations

Radiation-resistant and repair-proficient human tumor cells may be associated with radiotherapy failure in head- and neck-cancer patients.

1986 • 176 citations

The relationship between growth rate, labelling index and histological type of human solid tumours

1973 • 160 citations

Radiation-induced Potentially Lethal Damage: DNA Lesions Susceptible to Fixation

1988 • 143 citations

Factors Influencing the Repair of Potentially Lethal Radiation Damage in Growth-Inhibited Human Cells

1973 • 131 citations

The repair-misrepair model of cell survival

1980 • 129 citations

Initial Slope of Radiation Survival Curves Is Characteristic of the Origin of Primary and Established Cultures of Human Tumor Cells and Fibroblasts

1987 • 118 citations

Re-evaluation ofin VitroRadiosensitivity of Human Fibroblasts of Different Genetic Origins

1986 • 109 citations

Cellular repair factors influencing radiocurability of human malignant tumours

1982 • 108 citations

Differential responses to x-irradiation of subpopulations of two heterogeneous human carcinomas in vitro.

1982 • 104 citations

The radiobiology of human neuroblastoma

1985 • 94 citations

The shape of dose-survival curves for mammalian cells and repair of potentially lethal damage analyzed by hypertonic treatment.

1981 • 85 citations

Radiosensitivity and Growth Parametersin Vitroof Three Human Melanoma Cell Strains

1978 • 73 citations

Response of Human Osteosarcomain Vitroto Irradiation: Evidence for Unusual Cellular Repair Activity

1977 • 58 citations

Radiation Response Characteristics of Human Cells in Vitro

1988 • 52 citations

An explanatory hypothesis for early- and late-effect parameter values in the LQ model

1987 • 51 citations

Differential Response of Rapidly and Slowly Proliferating Human Cells to X Irradiation

1969 • 48 citations

The differential response of human tumours to fractionated radiation may be due to a post-irradiation repair process

1982 • 45 citations

The maximum recovery potential of human tumor cells may predict clinical outcome in radiotherapy

1987 • 42 citations

Cell-Cycle-Dependent Recovery from Heavy-Ion Damage in G 1 -Phase Cells

1985 • 40 citations

Radioresistant and repair proficient cells may determine radiocurability in human tumors

1986 • 35 citations

Fraction size and the repair of potentially lethal radiation damage in a human melanoma cell line. Possible implications for radiotherapy.

1982 • 33 citations

In Vitro radiation studies on Ewing's Sarcoma cell lines and human bone marrow: Application to the clinical use of total body irradiation (TBI)

1984 • 32 citations

Repair of potentially lethal x ray damage and possible applications to clinical radiotherapy

1983 • 30 citations

Correlation between PLD repair capacity and the survival curve of human fibroblasts in exponential growth phase: analysis in terms of several parameters.

1988 • 27 citations

The Effect of pH on Potentially Lethal Damage Recovery in A549 Cells

1986 • 27 citations

Radioresistance in some human tumor cells conferred in vitro by repair of potentially lethal X-ray damage.

1982 • 25 citations

Potentially lethal damage repair in human cells

1987 • 23 citations

The role of dna repair processes in the response of human tumors to fractionated radiotherapy

1984 • 23 citations

Radiosensitization of human tumor cells by alpha‐difluoromethylornithine

1986 • 20 citations

RBE and OER of π⁻mesons for damage to cultured T−1 cells of human kidney origin

1972 • 20 citations

Radiation response of cultured human carcinoembryonic antigen-producing colon adenocarcinoma cells

1977 • 19 citations

In vitro effects of N,N-dimethylformamide on sublethal and potentially lethal damage recovery processes after X-irradiation in heterogeneous human colon tumor cells.

1985 • 11 citations

Possible explanation of radioresistance of glioblastoma in situ

1983 • 8 citations