Duplications of Complement and Non‐Complement Genes of the H‐2S Region: Evolutionary Aspects of the C4 Isotypes and Molecular Analysis of their Expression Variants

An Efficient mRNA‐Dependent Translation System from Reticulocyte Lysates

1976 • 3,994 citations

HUMAN PLASMA PROTEINASE INHIBITORS

1983 • 2,129 citations

Similar Amino Acid Sequences: Chance or Common Ancestry?

1981 • 855 citations

The Metabolic Basis of Inherited Disease

1983 • 757 citations

Rapid duplication and loss of genes coding for the alpha chains of hemoglobin.

1980 • 531 citations

Two genes encoding steroid 21-hydroxylase are located near the genes encoding the fourth component of complement in man.

1985 • 492 citations

A molecular map of the immune response region from the major histocompatibility complex of the mouse

1982 • 466 citations

THE ORGANIZATION, EXPRESSION, AND EVOLUTION OF ANTIBODY GENES AND OTHER MULTIGENE FAMILIES

1975 • 446 citations

The structural basis of the multiple forms of human complement component C4

1984 • 419 citations

Mapping of steroid 21-hydroxylase genes adjacent to complement component C4 genes in HLA, the major histocompatibility complex in man.

1985 • 371 citations

A comparison of the properties of two classes, C4A and C4B, of the human complement component C4.

1984 • 296 citations

HLA-linked congenital adrenal hyperplasia results from a defective gene encoding a cytochrome P-450 specific for steroid 21-hydroxylation.

1984 • 291 citations

H-2 haplotypes, genes, and antigens: Second listing

1982 • 283 citations

The molecular basis for the difference in immune hemolysis activity of the Chido and Rodgers isotypes of human complement component C4.

1984 • 237 citations

Molecular map of the murine S region.

1983 • 185 citations

Multiple forms of cytochrome P-450 and the importance of molecular biology and evolution

1982 • 145 citations

Report of the committee on the genetic constitution of chromosome 6

1984 • 140 citations

Polymorphism of human complement component C4

1985 • 136 citations

Two steroid 21-hydroxylase genes are located in the murine S region

1984 • 135 citations

Hormonal inducibility of rat α2u globulin genes in transfected mouse cells

1981 • 131 citations

Autolytic fragmentation of complement components C3 and C4 under denaturing conditions, a property shared with α 2-macroglobulin

1981 • 128 citations

A sex-limited serum protein variant in the mouse: Inheritance and association with the H-2 region

1970 • 127 citations

A DNA polymorphism, consistent with gene duplication, correlates with high renin levels in the mouse submaxillary gland

1982 • 126 citations

The origin and evolution of protein superfamilies.

1976 • 124 citations

Molecular Characterization of the Ss and Slp (C4) Proteins of the Mouse H-2 Complex: Subunit Composition, Chain Size Polymorphism, and an Intracellular (Pro-Ss) Precursor

1978 • 121 citations

Immunochemical characterization of murine H-2 controlled Ss (serum substance) protein through identification of its human homologue as the fourth component of complement.

1975 • 120 citations

Use of a cDNA clone for the fourth component of human complement (C4) for analysis of a genetic deficiency of C4 in guinea pig.

1983 • 113 citations

Genetic variation in glycosylation of the fourth component of murine complement. Association with hemolytic activity.

1982 • 108 citations

Structural and functional differences between the H-2 controlled Ss and Slp proteins.

1978 • 94 citations

Cloning of a human complement component C4 gene.

1983 • 89 citations

Complement polymorphism, the major histocompatibility complex and associated diseases: a speculation.

1983 • 88 citations

Differential nuclease sensitivity of the ovalbumin and β-globin chromatin regions in erythrocytes and oviduct cells of laying hen

1980 • 87 citations

Tracts of high or low sequence divergence in the mouse major histocompatibility complex.

1984 • 86 citations

The Role of Natural Selection in Human Evolution

1977 • 86 citations

Induction of Lymphocytic Leukemia, Lymphosarcoma, Reticulum Cell Sarcoma, and Osteogenic Sarcoma in the Syrian Golden Hamster by Oncogenic DNA Simian Virus 40 2

1973 • 82 citations

Multiple duplications of complement C4 gene correlate with H-2-controlled testosterone-independent expression of its sex-limited isoform, C4-Slp.

1985 • 67 citations

An endopeptidase inhibitor, similar to mammalian alpha 2-macroglobulin, detected in the hemolymph of an invertebrate, Limulus polyphemus.

1983 • 66 citations

TheFactor BandC2genes

1984 • 62 citations

Steroid 21-hydroxylase (cytochrome P-450) from porcine adrenocortical microsomes: microsequence analysis of cysteine-containing peptides

1983 • 59 citations

Liver mRNA probes disclose two cytochrome P-450 genes duplicated in tandem with the complement C4 loci of the mouse H-2S region.

1985 • 58 citations

Report of the committee on the genetic constitution of chromosome 6

1982 • 57 citations

The mouse Rn locus: S allele of the renin regulator gene results from a single structural gene duplication.

1982 • 56 citations

Characterization of a Constitutive Variant of the Murine Serum Protein Allotype, Slp

1976 • 53 citations

cDNA clone spanning the alpha-gamma subunit junction in the precursor of the murine fourth complement component (C4).

1983 • 51 citations

Inherited Polymorphism of Guinea Pig Factor B and C4: Evidence for Genetic Linkage between the C4 and Bf Loci

1977 • 49 citations

Identification and partial characterization of the secreted form of the fourth component of human complement: evidence that it is different from major plasma form.

1983 • 44 citations

Female expression of the H-2-linked sex-limited protein (Slp) due to non-H-2 genes

1980 • 44 citations

Isolation of cDNA clones specifying the fourth component of mouse complement and its isotype, sex-limited protein.

1984 • 41 citations

Biosynthesis of C4 by mouse peritoneal macrophages. I. Characterization of an in vitro culture system and comparison of C4 synthesis by "low" vs "high" C4 strains.

1982 • 40 citations

The Complement Components of the Major Histocompatibility Locu

1984 • 38 citations

TheC4andSlpgenes of the complement region of the murineH-2major histocompatibility complex

1984 • 37 citations

Nucleotide sequence of complementary DNA and derived amino acid sequence of murine complement protein C3

1984 • 37 citations

Expression of hemolytically active murine fourth component of complement in transfected L cells

1984 • 34 citations

Genes for murine fourth complement component (C4) and sex-limited protein (Slp) identified by hybridization to C4- and Slp-specific cDNA.

1984 • 33 citations

A case of no sex-limitation of Slp in the murineH-2 complex

1975 • 31 citations

Structural and functional characterization of an incompletely processed form of murine C4 and Slp.

1982 • 30 citations

Mouse complement components C3 and C4. Characterization of their messenger RNA and molecular cloning of complementary DNA for C3.

1981 • 29 citations

Cultured hepatocytes from mouse strains expressing high and low levels of the fourth component of complement differ in rate of synthesis of the protein.

1983 • 29 citations

Amino acid sequence of a polymorphic segment from fragment C4d of human complement component C4

1983 • 27 citations

Characterization of the Mr difference between secreted murine fourth component of complement and the major plasma form: evidence for carboxyl-terminal cleavage of the alpha chain.

1982 • 26 citations

How does a Bacillus split its septum right down the middle?

1985 • 24 citations

H-2 S region determined polymorphic variants of the C4, Slp, C2, and B complement proteins: A compilation

1982 • 23 citations

Sequence heterogeneity of murine complementary DNA clones related to the C4 and C4-Slp isoforms of the fourth complement component

1984 • 22 citations

Differential DNase I sensitivity of the albumin and alpha-fetoprotein genes in chromatin from rat tissues and cell lines.

1984 • 22 citations

The murine sex-limited protein (Slp): reassessment of its sex limitation.

1982 • 20 citations

Variation in the glycosylation of the murine sex-limited protein: comparison with the fourth component of murine complement.

1983 • 19 citations

Multiple non-allelic genes encoding pancreatic alpha-amylase of mouse are expressed in a strain-specific fashion.

1984 • 19 citations

Structure and activation of complement components C2 and Factor B

1984 • 18 citations

Restriction fragment length polymorphism of c4 genes in mice with t chromosomes

1985 • 18 citations

Subdivision of the S region of the mouse major histocompatibility complex by identification of genomic polymorphisms of the class III genes

1984 • 17 citations

Identification of H-2-controlled structural variants of the murine Slp protein and demonstration of cis-regulation of its expression.

1981 • 14 citations

Gene-specific probes demonstrate selective duplications of the C4-Slp gene in the H-2S alleles associated with a testosterone-independent expression of this isotype

1985 • 14 citations

cis-Interacting genes in the S region of the murine major histocompatibility complex

1981 • 13 citations

Étude des Salmonella possédant les facteurs antigéniques 6,7:c:1,5

1985 • 13 citations

Molecular genetics of the S region of the murine H-2 major histocompatibility complex

1985 • 6 citations

The polymorphism of the complement genes in HLA

1985 • 6 citations

Mouse sip: Female expression due to a dominant non-H-2 gene in wild mice

1982 • 4 citations