Structure and activation of complement components C2 and Factor B

Atlas of protein sequence and structure

1965 • 4,462 citations

Structural basis of the activation and action of trypsin

1978 • 669 citations

Blood Coagulation

1980 • 562 citations

The Proteolytic Activation Systems of Complement

1981 • 479 citations

Primary structural analysis of the polypeptide portion of human C5a anaphylatoxin. Polypeptide sequence determination and assignment of the oligosaccharide attachment site in C5a.

1978 • 253 citations

The Alternative Pathway C3/C5 Convertase: Chemical Basis of Factor B Activation

1979 • 201 citations

ENHANCEMENT OF THE HEMOLYTIC ACTIVITY OF THE SECOND COMPONENT OF HUMAN COMPLEMENT BY OXIDATION

1967 • 189 citations

Internal homologies of the Ba fragment from human complement component Factor B, a class III MHC antigen.

1984 • 129 citations

Third component of human complement: structural analysis of the polypeptide chains of C3 and C3b

1979 • 97 citations

6 The Structure of Chymotrypsin

1971 • 84 citations

Isolation of cDNA clones for human complement component C2.

1984 • 78 citations

Characterization of the mRNA and cloned cDNA specifying the third component of mouse complement.

1982 • 78 citations

The purification and properties of the second component of guinea-pig complement

1982 • 72 citations

Limited proteolysis of complement components C2 and factor B. Structural analogy and limited sequence homology

1979 • 70 citations

The Serine Protease Nature of the C3 and C5 Convertases of the Classical and Alternative Complement Pathways

1976 • 68 citations

Ultrastructure of cobra venom factor-dependent C3/C5 convertase and its zymogen, factor B of human complement.

1982 • 64 citations

Factor D̄ of the alternative pathway of human complement. Purification, alignment and N-terminal amino acid sequences of the major cyanogen bromide fragments, and localization of the serine residue at the active site

1980 • 50 citations

Complete amino acid sequence of the catalytic chain of human complement subcomponent C.hivin.1r

1983 • 50 citations

Complement activation by the properdin system: formation of a stoichiometric, C3 cleaving complex of properdin factor B with C3b

1977 • 49 citations

Amino-terminal sequence of human factor B of the alternative complement pathway and its cleavage fragments, Ba and Bb

1980 • 42 citations

Partial sequence of human complement component factor B: novel type of serine protease.

1980 • 41 citations

Isolation, characterization and N-terminal sequences of the CNBr-cleavage peptides from human complement Factor B. Localization of a free thiol group and a sequence defining the site cleaved by factor D

1982 • 41 citations

Structural evidence that complement factor B constitutes a novel class of serine protease.

1980 • 32 citations

The reaction of iodine and thiol-blocking reagents with human complement components C2 and factor B. Purification and N-terminal amino acid sequence of a peptide from C2a containing a free thiol group

1983 • 30 citations

Amino acid sequence of the Bb fragment from complement Factor B. Sequence of the major cyanogen bromide-cleavage peptide (CB-II) and completion of the sequence of the Bb fragment

1983 • 29 citations

Complement

1979 • 27 citations

The serine proteinase chain of human complement component C̅1s. Cyanogen bromide cleavage and N-terminal sequences of the fragments

1983 • 26 citations

5 Chymotrypsinogen: X-Ray Structure

1971 • 26 citations

Amino acid sequence of the Bb fragment from human complement Factor B. Alignment of the cyanogen bromide-cleavage peptides

1983 • 12 citations

Amino acid sequence of a CNBr fragment of human complement component Cls containing the active-site serine residue

1982 • 4 citations