FPL 55712 — An antagonist of slow reacting substance of anaphylaxis (SRS-A): A review

THE PATHOLOGY OF ASTHMA, WITH SPECIAL REFERENCE TO CHANGES IN THE BRONCHIAL MUCOSA

1960 • 1,014 citations

The release of histamine and formation of a slow‐reacting substance (SRS‐A) during anaphylactic shock

1960 • 638 citations

Selective Inhibitor of Slow Reacting Substance of Anaphylaxis

1973 • 443 citations

AN EOSINOPHIL LEUKOCYTE CHEMOTACTIC FACTOR OF ANAPHYLAXIS

1971 • 266 citations

THE CAT LUNG STRIP AS AN in vitro PREPARATION OF PERIPHERAL AIRWAYS: A COMPARISON OF β‐ADRENOCEPTOR AGONISTS, AUTACOIDS AND ANAPHYLACTIC CHALLENGE ON THE LUNG STRIP AND TRACHEA

1976 • 228 citations

Bronchial Biopsy in Chronic Bronchitis and Asthma

1960 • 200 citations

RELEASE OF MEDIATORS OF ANAPHYLAXIS: INHIBITION OF PROSTAGLANDIN SYNTHESIS AND THE MODIFICATION OF RELEASE OF SLOW REACTING SUBSTANCE OF ANAPHYLAXIS AND HISTAMINE

1978 • 190 citations

Inactivation of Slow Reacting Substance of Anaphylaxis by Human Eosinophil Arylsulfatase

1975 • 189 citations

The physicochemical characteristics and purification of slow-reacting substance of anaphylaxis.

1973 • 167 citations

Slow Reacting Substance and Related Compounds

1962 • 166 citations

Growth Hormone and Premature Ageing

1973 • 163 citations

The tracheal chain; a preparation for the study of antispasmodics with particular reference to bronchodilator drugs.

1947 • 151 citations

Bronchial asthma: the possible role of the chemical mediators of immediate hypersensitivity in the pathogenesis of subacute chronic disease.

1975 • 150 citations

Tracheal mucous velocity in normal man and patients with obstructive lung disease: effects of terbutaline.

1974 • 149 citations

The Physicochemical Characteristics and Purification of Slow-Reacting Substance of Anaphylaxis

1973 • 146 citations

BRONCHOCONSTRICTOR ACTION AND ANTAGONISM OF A SLOW‐REACTING SUBSTANCE FROM ANAPHYLAXIS OF GUINEA‐PIG ISOLATED LUNG

1964 • 112 citations

On the structure of slow reacting substance of anaphylaxis: Evidence of biosynthesis from arachidonic acid

1977 • 111 citations

Inactivation of slow reacting substance of anaphylaxins (SRS-A) by arylsulfatases.

1974 • 109 citations

Inactivation of Slow Reacting Substance of Anaphylaxis (SRS-A) by Arylsulfatases

1974 • 95 citations

Tracheal mucous transport in experimental canine asthma

1975 • 88 citations

Some bronchoconstricting and bronchodilating responses of human isolated bronchi: Evidence for the existence of α-adrenoceptors

1971 • 85 citations

Disodium Cromoglycate

1970 • 74 citations

Prostaglandin, slow-reacting substance, and histamine release from anaphylactic guinea-pig hearts, and its pharmacological modification

1975 • 73 citations

Disodium cromoglycate. Activity in three in vitro models of the immediate hypersensitivity reaction in lung.

1970 • 71 citations

Release of Slow Reacting Substance (SRS) from Rat Basophilic Leukemia (RBL-1) Cells

1977 • 69 citations

Blockade by Polyphloretin Phosphate of the Prostaglandin F2α, Action on Isolated Human Bronchi

1971 • 63 citations

Antagonism of antigen-induced contraction of guinea pig and human airways

1977 • 60 citations

The Schultz-Dale reaction: A review

1978 • 58 citations

The effect of histamine antagonists on antigen-induced contractions of sensitized human bronchus in vitro [proceedings].

1977 • 56 citations

MEDIATORS OF PASSIVE LUNG ANAPHYLAXIS IN THE RAT

1975 • 52 citations

Further studies on the SRS-A antagonist FPL 55712.

1977 • 49 citations

Spasmolytic action of histamine in airway smooth muscle of horse

1978 • 48 citations

REDUCTION OF ANTIGEN‐INDUCED CONTRACTION OF SENSITIZED HUMAN BRONCHUS in vitro BY INDOMETHACIN

1975 • 45 citations

Anaphylactic Shock in the Monkey: its Hemodynamics and Mediators¹

1977 • 44 citations

Chemotactic Deactivation of Human Eosinophils by the Eosinophil Chemotactic Factor of Anaphylaxis

1975 • 41 citations

Anaphylaxis and the release of active substances in the lungs

1977 • 39 citations

Polymorphism of Human Enzyme Proteins

1971 • 30 citations

Prostaglandin release by slow reacting substance from guinea pig and human lung tissue

1977 • 30 citations

Role of amines in anaphylactic contraction of guinea pig isolated smooth muscle

1974 • 30 citations

THE PHARMACOLOGY OF ANAPHYLAXIS IN THE CHICKEN INTESTINE

1976 • 29 citations

Autacoid and anaphylactic reactivity of pulmonary and hepatic smooth musculature of the cat

1977 • 28 citations

The Immunological Release of Slow-Reacting Substance of Anaphylaxis from Bovine Lung

1974 • 28 citations

Antagonism of Slow Reacting Substance by Polyphloretin Phosphate on Isolated Human Bronchi

1971 • 25 citations

INVESTIGATION OF THE ROLE OF HISTAMINE IN ANTIGEN‐INDUCED BRONCHOCONSTRICTION IN THE ASCARIS‐HYPERSENSITIVE DOG

1978 • 24 citations

Effects of bovine SRS-A (SRS-Abov) on bovine respiratory tract and lung vasculature in vitro

1977 • 21 citations

The effect of metiamide in in vitro and in vivo canine models of type I hypersensitivity reactions

1977 • 21 citations

Comparative Studies of Two Models of Allergic Respiratory Disease

1967 • 20 citations

Histamine relaxes constricted trachea and bronchi of horse

1977 • 19 citations

Studies in Anaphylaxis in the Rabbit: IV. On the Simonds Explanation of the Different Pathology of Acute Anaphylactic Shock in Different Animal SpeciesV. On the Role of Unstriped Muscle in Acute Anaphylaxis in the Rabbit

1932 • 19 citations

Pharmacologic Regulation of Antigen-Induced Mediator Release from Canine Lung

1978 • 16 citations

Pharmacological study of chicken airway smooth muscle

1978 • 15 citations

A pharmacological study of SRS-A on the bovine cutaneous vasculature

1977 • 15 citations

Release of prostaglandins and rabbit aorta contracting substance (RCS) from guinea-pig lung by slow reacting substance of anaphylaxis (SRS-A) [proceedings].

1977 • 15 citations

Inhibition of eosinophil chemotaxis by the antagonist of slow reacting substance of anaphylaxis—compound FPL 55712

1974 • 12 citations

Studies in Anaphylaxis in the Rabbit

1932 • 10 citations

Inhibition of antigen-induced tone in isolated trachea

1975 • 10 citations

THE EFFECT OF CATECHOLAMINES ON THE in vivo AND in vitro RESPONSES OF THE CAT LUNG DURING ANAPHYLAXIS

1977 • 10 citations

An eosinophilotactic factor derived from rat mast cells

1975 • 9 citations

Surveillance of ambulatory asthmatics by means of total circulating eosinophil count.

1978 • 7 citations