Amphotericin B preparations: a maximum tolerated dose in severe invasive fungal infections?

Liposomal Amphotericin B for Empirical Therapy in Patients with Persistent Fever and Neutropenia

1999 • 1,184 citations

Amphotericin B: 30 Years of Clinical Experience

1990 • 1,011 citations

Antifungal and Surgical Treatment of Invasive Aspergillosis: Review of 2,121 Published Cases

1990 • 918 citations

Amphotericin B Lipid Complex for Invasive Fungal Infections: Analysis of Safety and Efficacy in 556 Cases

1998 • 631 citations

A randomized comparison of liposomal versus conventional amphotericin B for the treatment of pyrexia of unknown origin in neutropenic patients

1997 • 437 citations

Lipid Formulations of Amphotericin B: Clinical Efficacy and Toxicities

1998 • 396 citations

Liposomal amphotericin B compared with amphotericin B deoxycholate in the treatment of documented and suspected neutropenia‐associated invasive fungal infections

1998 • 321 citations

Randomized, Double‐Blind Clinical Trial of Amphotericin B Colloidal Dispersion vs. Amphotericin B in the Empirical Treatment of Fever and Neutropenia

1998 • 301 citations

Efficacy of amphotericin B encapsulated in liposomes (AmBisome) in the treatment of invasive fungal infections in immunocompromised patients

1991 • 281 citations

Liposomal and Lipid Formulations of Amphotericin B

1992 • 269 citations

An EORTC International Multicenter Randomized Trial (EORTC Number 19923) Comparing Two Dosages of Liposomal Amphotericin B for Treatment of Invasive Aspergillosis

1998 • 259 citations

Distribution and Activity of Amphotericin B in Humans

1985 • 228 citations

Th1 and Th2 cytokines in mice with invasive aspergillosis

1997 • 216 citations

Amphotericin B Lipid Complex Compared with Amphotericin B in the Treatment of Cryptococcal Meningitis in Patients with AIDS

1996 • 201 citations

Favorable outcome of invasive aspergillosis in patients with acute leukemia.

1987 • 190 citations

Efficacy of Unilamellar Liposomal Amphotericin B in Treatment of Pulmonary Aspergillosis in Persistently Granulocytopenic Rabbits: The Potential Role of Bronchoalveolar D-Mannitol and Serum Galactomannan as Markers of Infection

1994 • 187 citations

Safety, Tolerance, and Pharmacokinetics of a Small Unilamellar Liposomal Formulation of Amphotericin B (AmBisome) in Neutropenic Patients

1998 • 182 citations

The Effect of Ketoconazole on Amphotericin B in a Model of Disseminated Aspergillosis

1985 • 175 citations

Liposomal amphotericin B in the treatment of fungal infections in neutropenic patients: a single‐centre experience of 133 episodes in 116 patients

1994 • 174 citations

Amphotericin B colloidal dispersion vs. amphotericin B as therapy for invasive aspergillosis.

1997 • 163 citations

The Safety and Efficacy of Amphotericin B Colloidal Dispersion in the Treatment of Invasive Mycoses

1995 • 144 citations

Treatment of disseminated mycotic infections

1968 • 141 citations

Aspergillus and Aspergillosis

1988 • 135 citations

Liposomal Amphotericin B (AmBisome) Therapy in Invasive Fungal Infections

1995 • 134 citations

Combination Therapy of Experimental Candidiasis, Cryptococcosis and Aspergillosis in Mice

1982 • 120 citations

Pretreatment Regimens for Adverse Events Related to Infusion of Amphotericin B

1995 • 116 citations

Phase I Study of Amphotericin B Colloidal Dispersion for the Treatment of Invasive Fungal Infections after Marrow Transplant

1996 • 115 citations

Combination Therapy of Experimental Candidiasis, Cryptococcosis, Aspergillosis and Wangiellosis in Mice

1987 • 114 citations

The Discovery and Development of Amphotericin B

1968 • 105 citations

Pharmacokinetics of liposomal amphotericin B (Ambisome) in critically ill patients

1997 • 102 citations

Liposomal amphotericin B (AmBisome) reduces dissemination of infection ad compared with amphotericin B deoxycholate (Fungizone) in a rat model of pulmonary aspergillosis

1996 • 75 citations

Double-blind randomized study of the effect of infusion rates on toxicity of amphotericin B

1992 • 74 citations

Efficacy of amphotericin B lipid complex injection (ABLC) in bone marrow transplant recipients with life-threatening systemic mycoses

1997 • 74 citations

Effect of Immunosuppression and Amphotericin B on Aspergillus Antigenemia in an Experimental Model

1988 • 71 citations

Dose-dependent antifungal activity and nephrotoxicity of amphotericin B colloidal dispersion in experimental pulmonary aspergillosis

1994 • 69 citations

Amphotericin B lipid complex (ABLC) for the treatment of confirmed or presumed fungal infections in immunocompromised patients with hematologic malignancies

1997 • 69 citations

Liposomal amphotericin‐B (AmBisome)® treatment in solid organ and bone marrow transplant recipients. Efficacy and safety evaluation

1990 • 65 citations

Amphotericin B liposomes with prolonged circulation in blood: in vitro antifungal activity, toxicity, and efficacy in systemic candidiasis in leukopenic mice

1995 • 60 citations

Treatment of Acute Myeloid Leukemia with Cytokines: Effect on Duration of Neutropenia and Response to Infections

1998 • 58 citations

Long-Circulating Immunoliposomal Amphotericin B against Invasive Pulmonary Aspergillosis in Mice

1998 • 51 citations

Liposomal and lipid-based formulations of amphotericin B.

1996 • 39 citations

Do variations in molecular structure affect the clinical efficacy and safety of lipid-based amphotericin B preparations?

1997 • 37 citations

Efficacy of Low-Dose Dopamine in Preventing Amphotericin B Nephrotoxicity in Bone Marrow Transplant Patients and Leukemia Patients

1998 • 27 citations

Safety of amphotericin B colloidal dispersion

1997 • 27 citations

Accumulation of Amphotericin B in Human Macrophages Enhances Activity againstAspergillus fumigatusConidia: Quantification of Conidial Kill at the Single-Cell Level

1998 • 27 citations

Efficacy of escalating doses of liposomal amphotericin B (AmBisome) against hematogenous Candida lusitaniae and Candida krusei infection in neutropenic mice

1994 • 26 citations

Liposomal amphotericin B (AmBisome®) treatment of invasive fungal infections in immunocompromised children

1993 • 25 citations

In-Vitro and In-Vivo Models to Study the Activity of Antifungals against Aspergillus

1988 • 24 citations

Liposomal amphotericin B (AmBisome) therapy in invasive fungal infections. Evaluation of United Kingdom compassionate use data

1995 • 23 citations

In-vitro effects of liposome-encapsulated amphotericin B (AmBisome) and amphotericin B-deoxycholate (Fungizone) on the phagocytic and candidacidal function of human polymorphonudear leucocytes

1992 • 23 citations

Experimental murine aspergillosis. Comparison of amphotericin B and a new polyene antifungal drug, SCH 28191.

1984 • 22 citations

Changes in the natural history of invasive pulmonary aspergillosis in neutropenic leukemic patients.

1996 • 14 citations

Influence of six antifungal agents on the chemiluminescence response of mouse spleen cells

1986 • 14 citations

Tuberculosis of the mouth and throat

1960 • 12 citations