Lipid Formulations of Amphotericin B: Clinical Efficacy and Toxicities

A randomized comparison of liposomal versus conventional amphotericin B for the treatment of pyrexia of unknown origin in neutropenic patients

1997 • 437 citations

Liposomal Amphotericin B for the Treatment of Systemic Fungal Infections in Patients with Cancer: A Preliminary Study

1985 • 412 citations

Lipid Formulations of Amphotericin B: Recent Progress and Future Directions

1996 • 400 citations

Efficacy of amphotericin B encapsulated in liposomes (AmBisome) in the treatment of invasive fungal infections in immunocompromised patients

1991 • 281 citations

Liposomal and Lipid Formulations of Amphotericin B

1992 • 269 citations

Liposomal amphotericin B (AmBisome): safety data from a phase II/III clinical trial

1991 • 236 citations

Distribution and Activity of Amphotericin B in Humans

1985 • 228 citations

Unusual lipid structures selectively reduce the toxicity of amphotericin B.

1988 • 225 citations

Chemotherapy of Systemic Mycoses

1974 • 218 citations

Treatment of hepatosplenic candidiasis with liposomal-amphotericin B.

1987 • 217 citations

Amphotericin B Lipid Complex Compared with Amphotericin B in the Treatment of Cryptococcal Meningitis in Patients with AIDS

1996 • 201 citations

LIPOSOMAL AMPHOTERICIN B PREVENTS INVASIVE FUNGAL INFECTIONS IN LIVER TRANSPLANT RECIPIENTS

1995 • 178 citations

Use of liposomes as injectable-drug delivery systems

1989 • 176 citations

Liposomal amphotericin B in the treatment of fungal infections in neutropenic patients: a single‐centre experience of 133 episodes in 116 patients

1994 • 174 citations

Randomized double-blind study of liposomal amphotericin B (Ambisome) prophylaxis of invasive fungal infections in bone marrow transplant recipients.

1993 • 164 citations

Amphotericin B colloidal dispersion vs. amphotericin B as therapy for invasive aspergillosis.

1997 • 163 citations

Amphotericin B lipid complex therapy of experimental fungal infections in mice

1991 • 160 citations

Invasive fungal sinusitis in patients undergoing bone marrow transplantation.

1993 • 156 citations

The Safety and Efficacy of Amphotericin B Colloidal Dispersion in the Treatment of Invasive Mycoses

1995 • 144 citations

Liposomal Amphotericin B (AmBisome) Therapy in Invasive Fungal Infections

1995 • 134 citations

Overview of liposomes

1991 • 129 citations

Amphotericin B Lipid Complex (Ablc™): A Molecular Rationale for the Attenuation of Amphotericin B Related Toxicities

1993 • 121 citations

Treatment of cryptococcosis with liposomal amphotericin B (AmBisome) in 23 patients with AIDS

1993 • 119 citations

Phase I Study of Amphotericin B Colloidal Dispersion for the Treatment of Invasive Fungal Infections after Marrow Transplant

1996 • 115 citations

Meta-analysis of prophylactic or empirical antifungal treatment versus placebo or no treatment in patients with cancer complicated by neutropenia

1997 • 110 citations

Liposomes as carriers of antimicrobial agents

1987 • 104 citations

Rhinocerebral mucormycosis: Use of liposomal amphotericin B

1991 • 103 citations

Altered Tissue Distribution of Amphotericin B by Liposomal Encapsulation: Comparison of Normal Mice to Mice Infected with Candida albicans

1984 • 98 citations

Liposomal amphotericin B (AmBisome) in the treatment of fungal infections in neutropenic patients

1991 • 97 citations

Treatment of Experimental Invasive Aspergillosis with Novel Amphotericin B/Cholesterol-Sulfate Complexes

1989 • 92 citations

Rhinocerebral mucormycosis. Therapy with amphotericin B lipid complex

1996 • 89 citations

Amphotericin B-phospholipid interactions responsible for reduced mammalian cell toxicity

1992 • 89 citations

Dose-dependent antifungal activity and nephrotoxicity of amphotericin B colloidal dispersion in experimental pulmonary aspergillosis

1994 • 69 citations

Safety of liposomal amphotericin B (AmBisome) in 187 transplant recipients treated with cyclosporin.

1994 • 66 citations

Liposomes: Realizing Their Promise

1992 • 62 citations

Comparative efficacy of amphotericin B colloidal dispersion and amphotericin B deoxycholate suspension in treatment of murine coccidioidomycosis

1991 • 58 citations

Efficacy and safety of amphotericin B colloidal dispersion compared with those of amphotericin B deoxycholate suspension for treatment of disseminated murine cryptococcosis

1992 • 57 citations

Liposomal Amphotericin-B (AmBisome) for Treatment of Disseminated Fungal Infections in Two Infants of Very Low Birth Weight

1992 • 54 citations

Successful Treatment of Fungal Infections in Neutropenic Patients with Liposomal Amphotericin (AmBisome)—A Report on 40 Cases from a Single Centre

1992 • 40 citations

Apophysomyces elegans infection in a renal transplant recipient

1995 • 39 citations

Limited Toxicity of Prolonged Therapy with High Doses of Amphotericin B Lipid Complex

1995 • 38 citations

Characteristics of Lipid-Based Formulations That Influence Their Biological Behavior in the Plasma of Patients

1996 • 36 citations

Pulmonary toxicity during infusion of liposomal amphotericin B in two patients with acute leukemia

1995 • 35 citations

Phagocyte Transport as Mechanism for Enhanced Therapeutic Activity of Liposomal Amphotericin B

1994 • 35 citations

Influence of phospholipid/amphotericin B ratio and phospholipid type on in vitro renal cell toxicities and fungicidal activities of lipid-associated amphotericin B formulations

1992 • 34 citations

Successful treatment of cryptococcal meningitis with amphotericin B colloidal dispersion: report of four cases

1995 • 28 citations

Sodium Loading Treatment for Amphotericin B-Induced Nephrotoxicity

1990 • 26 citations

Successful treatment of invasive aspergillosis complicating prolonged treatment‐related neutropenia in acute myelogenous leukemia with amphotericin B lipid complex

1995 • 21 citations

High cure rate of invasive fungal infections in immunocompromised children using ambisome.

1994 • 20 citations

Experience with liposomal amphotericin B (AmBisome) in cryptococcal meningitis in AIDS

1991 • 18 citations

Amphotericin B Lipid Complex to Treat Invasive Fungal Infections in Cancer Patients: Report of Efficacy and Safety in 20 Patients

1995 • 17 citations

Successful treatment of zygomycosis of the paranasal sinuses with surgical debridement and amphotericin B colloidal dispersion

1993 • 15 citations

Successful Treatment of Aspergillus Vertebral Osteomyelitis with Amphotericin B Lipid Complex

1995 • 9 citations

Amphotericin B lipid complex for the treatment of presumed or confirmed fungal infections in immunocompromised patients with hematologic malignancies

1996 • 7 citations

AMPHOTERICIN B COLLOIDAL DISPERSION THERAPY FOR INVASIVE MYCOSIS

1994 • 3 citations