Methylation induced premeiotically in Ascobolus: coextension with DNA repeat lengths and effect on transcript elongation.

Cytosine methylation prevents binding to DNA of a HeLa cell transcription factor required for optimal expression of the adenovirus major late promoter.

1988 • 587 citations

CpG methylation of the cAMP-responsive enhancer/promoter sequence TGACGTCA abolishes specific factor binding as well as transcriptional activation.

1989 • 554 citations

Repression of genes by DNA methylation depends on CpG density and promoter strength: evidence for involvement of a methyl-CpG binding protein.

1992 • 472 citations

Rearrangement of duplicated DNA in specialized cells of Neurospora

1987 • 366 citations

Repeat-induced G-C to A-T Mutations in Neurospora

1989 • 353 citations

Role of an adenovirus E2 promoter binding factor in E1A-mediated coordinate gene control.

1987 • 290 citations

DNA sequence duplications trigger gene inactivation in Neurospora crassa.

1988 • 235 citations

Effect of regional DNA methylation on gene expression.

1985 • 232 citations

Isolation of genomic clones containing the amdS gene of Aspergillus nidulans and their use in the analysis of structural and regulatory mutations.

1983 • 232 citations

Aspergillus nidulans contains a single actin gene which has unique intron locations and encodes a γ-actin

1988 • 209 citations

Targeted transformation of Ascobolus immersus and de novo methylation of the resulting duplicated DNA sequences.

1989 • 158 citations

Transcription of the his3 gene region in Saccharomyces cerevisiae

1981 • 145 citations

Epimutation of repeated genes in Ascobolus immersus.

1992 • 133 citations

Site-specific methylation: effect on DNA modification methyltransferases and restriction endonucleases

1991 • 94 citations

How does the cell count the number of ectopic copies of a gene in the premeiotic inactivation process acting in Ascobolus immersus?

1990 • 77 citations

Isolation of Genomic Clones Containing the amdS Gene of Aspergillus nidulans and Their Use in the Analysis of Structural and Regulatory Mutations

1983 • 63 citations

Targeted Transformation of Ascobolus immersus and De Novo Methylation of the Resulting Duplicated DNA Sequences

1989 • 57 citations

Specificity of repeat-induced point mutation (RIP) in Neurospora: sensitivity of non-Neurospora sequences, a natural diverged tandem duplication, and unique DNA adjacent to a duplicated region.

1991 • 40 citations

Molecular cloning and characterization of the met2 gene from Ascobolus immersus

1988 • 38 citations

Stable allele replacement and unstable non-homologous integration events during transformation of Ascobolus immersus

1989 • 30 citations

Hemimethylation of DNA prevents chromatin expression.

1990 • 19 citations

Generation of new functional mutant alleles by premeiotic disruption of the Neurospora crassa am gene

1990 • 18 citations

[On an Ascomycete of interest for the study of certain aspects of the problem of gene structure].

1960 • 9 citations

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