Sec17p and HOPS, in distinct SNARE complexes, mediate SNARE complex disruption or assembly for fusion

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1998 • 2,456 citations

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1993 • 1,893 citations

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1998 • 1,032 citations

Using Antibodies: A Laboratory Manual

1998 • 1,012 citations

Sec18p (NSF)-Driven Release of Sec17p (α-SNAP) Can Precede Docking and Fusion of Yeast Vacuoles

1996 • 580 citations

A rab protein is required for the assembly of SNARE complexes in the docking of transport vesicles

1994 • 501 citations

A Ypt/Rab effector complex containing the Sec1 homolog Vps33p is required for homotypic vacuole fusion

2000 • 469 citations

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Rab1 Recruitment of p115 into a cis-SNARE Complex: Programming Budding COPII Vesicles for Fusion

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New Component of the Vacuolar Class C-Vps Complex Couples Nucleotide Exchange on the Ypt7 Gtpase to Snare-Dependent Docking and Fusion

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1994 • 392 citations

Ca2+/calmodulin signals the completion of docking and triggers a late step of vacuole fusion

1998 • 390 citations

Initial docking of ER-derived vesicles requires Uso1p and Ypt1p but is independent of SNARE proteins

1998 • 370 citations

Phox domain interaction with PtdIns(3)P targets the Vam7 t-SNARE to vacuole membranes

2001 • 362 citations

Defining the functions of trans-SNARE pairs

1998 • 343 citations

Sec1p Binds to SNARE Complexes and Concentrates at Sites of Secretion

1999 • 327 citations

Class C Vps Protein Complex Regulates Vacuolar SNARE Pairing and Is Required for Vesicle Docking/Fusion

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1995 • 262 citations

A Vacuolar v–t-SNARE Complex, the Predominant Form In Vivo and on Isolated Vacuoles, Is Disassembled and Activated for Docking and Fusion

1998 • 255 citations

Docking of Yeast Vacuoles Is Catalyzed by the Ras-like GTPase Ypt7p after Symmetric Priming by Sec18p (NSF)

1997 • 239 citations

Vacuole Fusion at a Ring of Vertex Docking Sites Leaves Membrane Fragments within the Organelle

2002 • 232 citations

Interdependent assembly of specific regulatory lipids and membrane fusion proteins into the vertex ring domain of docked vacuoles

2004 • 219 citations

Sly1 Binds to Golgi and ER Syntaxins via a Conserved N-Terminal Peptide Motif

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The Docking Stage of Yeast Vacuole Fusion Requires the Transfer of Proteins from a Cis-Snare Complex to a Rab/Ypt Protein

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The N-Ethylmaleimide-sensitive Fusion Protein and α-SNAP Induce a Conformational Change in Syntaxin

1995 • 210 citations

A Role for the deep orange and carnation Eye Color Genes in Lysosomal Delivery in Drosophila

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Sequential tethering of Golgins and catalysis of SNAREpin assembly by the vesicle-tethering protein p115

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The Effector Domain of Myristoylated Alanine-rich C Kinase Substrate Binds Strongly to Phosphatidylinositol 4,5-Bisphosphate

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Synaptic Core Complex of Synaptobrevin, Syntaxin, and SNAP25 Forms High Affinity -SNAP Binding Site

1995 • 174 citations

Homotypic vacuole fusion requires Sec17p (yeast alpha-SNAP) and Sec18p (yeast NSF).

1996 • 174 citations

Sly1 protein bound to Golgi syntaxin Sed5p allows assembly and contributes to specificity of SNARE fusion complexes

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Three v-SNAREs and Two t-SNAREs, Present in a Pentameric cis-SNARE Complex on Isolated Vacuoles, Are Essential for Homotypic Fusion

1999 • 166 citations

Epsin 1 Undergoes Nucleocytosolic Shuttling and Its Eps15 Interactor Nh2-Terminal Homology (Enth) Domain, Structurally Similar to Armadillo and Heat Repeats, Interacts with the Transcription Factor Promyelocytic Leukemia Zn2+ Finger Protein (Plzf)

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Vam3p structure reveals conserved and divergent properties of syntaxins.

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Hierarchy of protein assembly at the vertex ring domain for yeast vacuole docking and fusion

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Interactions between a Nuclear Transporter and a Subset of Nuclear Pore Complex Proteins Depend on Ran GTPase

1999 • 131 citations

Yeast homotypic vacuole fusion requires the Ccz1–Mon1 complex during the tethering/docking stage

2003 • 126 citations

Mammalian Late Vacuole Protein Sorting Orthologues Participate in Early Endosomal Fusion and Interact with the Cytoskeleton

2003 • 124 citations

The mouse organellar biogenesis mutant buff results from a mutation inVps33a, a homologue of yeastvps33andDrosophilacarnation

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A quantitative assay to measure homotypic vacuole fusion in vitro

1995 • 122 citations

Sec1p directly stimulates SNARE-mediated membrane fusion in vitro

2004 • 117 citations

A cycle of Vam7p release from and PtdIns 3-P–dependent rebinding to the yeast vacuole is required for homotypic vacuole fusion

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The riddle of the Sec1/Munc-18 proteins – new twists added to their interactions with SNAREs

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A soluble SNARE drives rapid docking, bypassing ATP and Sec17/18p for vacuole fusion

2004 • 101 citations

Gene replacement reveals that p115/SNARE interactions are essential for Golgi biogenesis

2004 • 98 citations

Sequential action of two GTPases to promote vacuole docking and fusion

2000 • 97 citations

Proteins Needed for Vesicle Budding from the Golgi Complex Are Also Required for the Docking Step of Homotypic Vacuole Fusion

2000 • 94 citations

Trans-SNARE interactions elicit Ca2+ efflux from the yeast vacuole lumen

2004 • 89 citations

Vac8p release from the SNARE complex and its palmitoylation are coupled and essential for vacuole fusion

2001 • 89 citations

Thelightgene ofDrosophila melanogasterencodes a homologue ofVPS41, a yeast gene involved in cellular-protein trafficking

1998 • 76 citations

A new role for a SNARE protein as a regulator of the Ypt7/Rab-dependent stage of docking

2000 • 68 citations

The Sec1/Munc18 Protein, Vps33p, Functions at the Endosome and the Vacuole ofSaccharomyces cerevisiae

2004 • 62 citations

Primary structure and biochemical characterization of yeast GTPase‐activating proteins with substrate preference for the transport GTPase Ypt7p

1999 • 60 citations

Functional Analysis of Conserved Structural Elements in Yeast Syntaxin Vam3p

2001 • 57 citations

The N-terminal Domain of the t-SNARE Vam3p Coordinates Priming and Docking in Yeast Vacuole Fusion

2001 • 55 citations

The Sec1p/Munc18 (SM) protein, Vps45p, cycles on and off membranes during vesicle transport

2003 • 47 citations

Resolution of organelle docking and fusion kinetics in a cell-free assay

2004 • 43 citations

The Docking of Primed Vacuoles Can Be Reversibly Arrested by Excess Sec17p (α-SNAP)

2000 • 43 citations

The Sec1p/Munc18 (SM) protein, Vps45p, cycles on and off membranes during vesicle transport

2012 • 42 citations