Factor VIII inhibitors in haemophiliacs: a single‐centre experience over 34 years, 1964–97

Inversions disrupting the factor VIII gene are a common cause of severe haemophilia A

1993 • 787 citations

Incidence of development of factor VIII and factor IX inhibitors in haemophiliacs

1992 • 613 citations

A More Uniform Measurement of Factor VIII Inhibitors

1975 • 498 citations

Recombinant Factor VIII for the Treatment of Previously Untreated Patients with Hemophilia A -- Safety, Efficacy, and Development of Inhibitors

1993 • 482 citations

The pathophysiology of the prethrombotic state in humans: insights gained from studies using markers of hemostatic system activation

1987 • 395 citations

A multicenter study of recombinant factor VIII (recombinate): safety, efficacy, and inhibitor risk in previously untreated patients with hemophilia A. The Recombinate Study Group.

1994 • 352 citations

Factor VIII gene inversions in severe hemophilia A: results of an international consortium study

1995 • 350 citations

Haemophilia A: Mutation Type Determines Risk of Inhibitor Formation

1995 • 336 citations

A More Uniform Measurement of Factor VIII Inhibitors

1975 • 316 citations

Factor VIII inhibitors in mild and moderate-severity haemophilia A. UK Haemophilia Centre Directors Organisation.

1998 • 193 citations

A Method for the Study of Antihaemophilic Globulin Inhibitors with Reference to Six Cases

1959 • 184 citations

Factor VIII Inhibitors in Mild and Moderate-severity Haemophilia A

1998 • 184 citations

Recombinant Factor VIII for the Treatment of Previously Untreated Patients with Hemophilia A

1993 • 183 citations

A Multicenter Study of Recombinant Factor VIII (Recombinate): Safety, Efficacy, and Inhibitor Risk in Previously Untreated Patients With Hemophilia A

1994 • 162 citations

Treatment of haemophilia and related disorders in Britain and Northern Ireland during 1976-80: report on behalf of the directors of haemophilia centres in the United Kingdom.

1983 • 139 citations

Prevalence of Inhibitors in a Population of 3435 Hemophilia Patients in France

1992 • 135 citations

Loss of high‐responder inhibitors in patients with severe hemophilia A and human immunodeficiency virus type 1 infection: A report from the multi‐center hemophilia cohort study

1993 • 118 citations

Controlled trial of hyposensitisation in children with food-induced hyperkinetic syndrome

1992 • 100 citations

The natural history of factor VIII inhibitors in patients with hemophilia A.

1984 • 85 citations

Haemophilia Treatment in the United Kingdom from 1969 to 1974

1977 • 69 citations

Factor VIII inhibitors.

1997 • 63 citations

Absence of Inhibitors in Previously Untreated Patients with Severe Haemophilia A after Exposure to a Single Intermediate Purity Factor VIII Product

1997 • 62 citations

HEMOPHILIA. A CLINICAL STUDY OF FORTY PATIENTS

1949 • 56 citations

Analysis of intron 22 inversions of the factor VIII gene in severe hemophilia A: implications for genetic counseling

1994 • 50 citations

Incidence of inhibitor development in a group of young hemophilia A patients treated exclusively with lyophilized cryoprecipitate

1993 • 47 citations

Incidence of Factor VIII Inhibitor Development in Severe Hemophilia A Patients Treated only with One Brand of Highly Purified Plasma-Derived Concentrate

1995 • 44 citations

Molecular etiology of factor VIII deficiency in hemophilia A

1995 • 11 citations

Successful long‐term treatment with porcine factor VIII of a patient with haemophilia A and an inhibitor to factor VIII

1996 • 7 citations