Detection of 4'‐phosphopantetheine at the thioester binding site for <scp>l</scp>‐valine of gramicidinS synthetase 2

A gas-liquid solid phase peptide and protein sequenator.

1981 • 2,238 citations

Interpreting mass spectra of multiply charged ions

1989 • 579 citations

The Mechanism of Enzyme Action

1954 • 429 citations

Nonribosomal biosynthesis of peptide antibiotics

1990 • 322 citations

Sequence and analysis of the genetic locus responsible for surfactin synthesis in Bacillus subtilis

1993 • 296 citations

Fast atom bombardment: A new mass spectrometric method for peptide sequence analysis

1981 • 260 citations

Gramicidin S biosynthesis operon containing the structural genes grsA and grsB has an open reading frame encoding a protein homologous to fatty acid thioesterases

1989 • 244 citations

Four homologous domains in the primary structure of GrsB are related to domains in a superfamily of adenylate‐forming enzymes

1992 • 240 citations

Four homologous domains in the primary structure of GrsB are related to domains in a superfamily of adenylate‐forming enzymes

1992 • 205 citations

Elucidation by FAB–MS of the structure of a new cardioactive peptide from Aplysia

1982 • 177 citations

Delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase from Aspergillus nidulans. Molecular characterization of the acvA gene encoding the first enzyme of the penicillin biosynthetic pathway

1991 • 164 citations

Nonribosomal polypeptide synthesis on polyenzyme templates

1973 • 145 citations

An active serine is involved in covalent substrate amino acid binding at each reaction center of gramicidin S synthetase.

1991 • 139 citations

The activation of amino acids for biosynthesis of gramicidin S.

1968 • 120 citations

Multidomain enzymes involved in peptide synthesis

1992 • 109 citations

Complete nucleotide sequence of the tycA gene coding the tyrocidine synthetase 1 fromBacillus brevis

1988 • 108 citations

The protein thiotemplate mechanism of synthesis for the peptide antibiotics produced by Bacillus brevis.

1973 • 97 citations

Biosynthesis of Small Peptides

1974 • 86 citations

Characterization of the srfA locus of Bacillus subtilis: only the valine‐activating domain of srfA is involved in the establishment of genetic competence

1993 • 57 citations

Pantetheine-Linked Peptide Intermediates in Gramicidin S and Tyrocidine Biosynthesis

1971 • 51 citations

Gramicidin S synthetase. Temperature dependence and thermodynamic parameters of substrate amino acid activation reactions

1985 • 21 citations

Formation of <scp>D</scp>‐Phe‐Pro‐Val‐cyclo‐Orn by gramicidin S synthetase in the absence of <scp>L</scp>‐leucine

1987 • 17 citations

Proteinchemical and Kinetic Features of Gramicidin S Synthetase

1989 • 15 citations