Plasma β-endorphin and cortisol levels in morphine-tolerant rats and in naloxone-induced withdrawal

Common precursor to corticotropins and endorphins

1977 • 1,106 citations

Self-administration of psychoactive substances by the monkey

1969 • 807 citations

Physiological parameters of morphine dependence in man—Tolerance, early abstinence, protracted abstinence

1969 • 264 citations

Formulation of a Morphine Implantation Pellet Suitable for Tolerance-Physical Dependence Studies in Mice

1970 • 223 citations

Corticotrophin‐releasing factor, vasopressin and pro‐opiomelanocortin mRNA responses to stress and opiates in the rat.

1988 • 217 citations

Differences in Hypothalamo-Pituitary-Adrenocortical Activity in the Rat after Acute and Prolonged Treatment with Morphine

1984 • 171 citations

Changes in hypothalamic preproenkephalin A mRNA following stress and opiate withdrawal

1987 • 161 citations

Secretion of Corticotrophin and Its Hypothalamic Releasing Factor in Response to Morphine and Opioid Peptides

1982 • 159 citations

β-Endorphin-like immunoreactivity in plasma, pituitaries and hypothalamus of rats following treatment with opiates

1978 • 116 citations

Rapid induction and quantitation of morphine dependence in the rat by pellet implantation

1977 • 86 citations

μ-, δ-, κ- and ϵ-Opioid receptor modulation of the hypothalamic-pituitary-adrenocortical (HPA) axis: subchronic tolerance studies of endogenous opioid peptides

1987 • 76 citations

Pharmacological Characterization of Opioid Receptors Influencing the Secretion of Corticotrophin Releasing Factor in the Rat

1986 • 74 citations

Differential Plasmaβ-Endorphin,β-Lipotropin, and Adrenocorticotropin Responses to Stress in Rats*

1985 • 62 citations

β-Endorphin stimulates corticosterone synthesis in isolated rat adrenal cells

1979 • 62 citations

Beta-endorphin-like immunoactivity in the plasma of heroin addicts and normal subjects

1980 • 61 citations

Impaired circadian rhythmicity of β-lipotrophin, β-endorphin and ACTH in heroin addicts

1984 • 61 citations

Identification of multiple opiate receptors through neuroendocrine responses. I. Effects of agonists.

1985 • 52 citations

D-Ala²-Met-Enkephalinamide, a Potent Opioid Peptide, Alters Pituitary-Adrenocortical Secretion in Rats*

1982 • 50 citations

Role of Alpha-Adrenergic Mechanism in Effects of Morphine on the Hypothalamo-Pituitary-Adrenocortical and Cardiovascular Systems in the Rat

1989 • 49 citations

N-allylnormorphine antagonism of the hypothermic effect of morphine in the rat following intracerebral and systemic administration.

1965 • 49 citations

Inquiry into endorphinergic feedback mechanisms during the development of opiate tolerance/dependence

1980 • 46 citations

Plasma corticosterone changes in response to central or peripheral administration of kappa and sigma opiate agonists.

1985 • 46 citations

On the site of action of naloxone-stimulated cortisol secretion in gilts

1988 • 38 citations

Effect of chronic morphine treatment on β-endorphine biosynthesis by the rat neurointermediate lobe

1981 • 33 citations

Reduced tolerance to morphine thermoregulatory effects in senescent rats

1981 • 32 citations

Morphine or Capsaicin Administration Alters the Secretion of Beta-Endorphin into the Hypophysial Portal Vasculature of the Rat

1986 • 29 citations

Withdrawal symptoms in morphine-dependent rats intracerebroventricularly injected with ACTH1–24 and with β-MSH

1981 • 27 citations

Effects of morphine on hypothalamic corticotropin-releasing factor (CRF), norepinephrine and dopamine in non-stressed and stressed rats.

1985 • 27 citations

Endogenous opioids in cerebrospinal fluid of opioid-dependent humans

1988 • 27 citations

Endorphins and Opiate Antagonists in Psychiatric Research

1982 • 25 citations

Effects of opiod antagonists and their quaternary analogs on temperature changes in morphine-dependent rats

1986 • 25 citations

ENDORPHIN LEVELS IN OPIOID‐DEPENDENT HUMAN SUBJECTS: A LONGITUDINAL STUDY*

1982 • 24 citations

Stimulation of ACTH release by naloxone: Central or peripheral action?

1985 • 12 citations

Differential alterations by chronic treatment with morphine of pro-opiomelanocortin mRNA levels in anterior as compared to intermediate pituitary lobes of rats

1985 • 10 citations

Opioid-neurotransmitter interactions: Significance in analgesia, tolerance and dependence

1984 • 10 citations

β-Endorphin-Like Immunoreactivity in CSF and Plasma of Neuropsychiatric Patients

1982 • 8 citations

Reduction of beta-endorphin levels in the amniotic fluid of heroin addicts.

1986 • 7 citations

Effect of selective monoamine oxidase inhibitors on the morphine-induced hypothermia in restrained rats

1987 • 6 citations