Role of Ribonucleotide Reductase and Deoxynucleotide Pools in the Oxygen‐Dependent Control of DNA Replication in Ehrlich Ascites Cells

Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours

1996 • 2,304 citations

The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA

1994 • 1,669 citations

INTERACTIONS BETWEEN DEOXYRIBONUCLEOTIDE AND DNA SYNTHESIS

1988 • 773 citations

Hypoxia induces accumulation of p53 protein, but activation of a G1-phase checkpoint by low-oxygen conditions is independent of p53 status.

1994 • 620 citations

Structure of ribonucleotide reductase protein R1

1994 • 571 citations

From RNA to DNA, Why So Many Ribonucleotide Reductases?

1993 • 525 citations

Structure and Function of the Escherichia coli Ribonucleotide Reductase Protein R2

1993 • 462 citations

Cdk-interacting protein 1 directly binds with proliferating cell nuclear antigen and inhibits DNA replication catalyzed by the DNA polymerase delta holoenzyme.

1994 • 415 citations

The tumore suppressor p53

1993 • 336 citations

Methods in Cancer Research

1979 • 318 citations

Cell cycle-dependent regulation of mammalian ribonucleotide reductase. The S phase-correlated increase in subunit M2 is regulated by de novo protein synthesis.

1984 • 244 citations

A model for the role of multiple cysteine residues involved in ribonucleotide reduction: amazing and still confusing

1992 • 210 citations

Continual presence of oxygen and iron required for mammalian ribonucleotide reduction: Possible regulation mechanism

1983 • 190 citations

Biochemical properties and biological effects of p53

1995 • 183 citations

Nucleotide pools of Novikoff rat hepatoma cells growing in suspension culture. I. Kinetics of incorporation of nucleosides into nucleotide pools and pool sizes during growth cycle

1971 • 181 citations

Eukaryotic DNA Replication: Viral and Plasmid Model Systems

1982 • 107 citations

DNA precursor pools and ribonucleotide reductase activity: distribution between the nucleus and cytoplasm of mammalian cells.

1985 • 98 citations

The Redox Centers of Ribonucleotide Reductase of Escherichia coli

1992 • 98 citations

The respiration of ascites tumour cells at low oxygen concentrations

1962 • 87 citations

From deoxynucleotides to DNA synthesis.

1978 • 82 citations

Detection of activities that interfere with the enzymatic assay of deoxyribonucleoside 5'-triphosphates.

1980 • 73 citations

Regulation of pyrimidine deoxyribonucleotide metabolism by substrate cycles in dCMP deaminase-deficient V79 hamster cells.

1987 • 69 citations

Evidence for the involvement of substrate cycles in the regulation of deoxyribonucleoside triphosphate pools in 3T6 cells.

1985 • 67 citations

Oxygen dependent regulation of DNA synthesis and growth of Ehrlich ascites tumor cells in vitro and in vivo.

1988 • 57 citations

Regulation of cell proliferation under extreme and moderate hypoxia: the role of pyrimidine (deoxy)nucleotides

1994 • 45 citations

Oxygen dependence of nuclear DNA replication in Ehrlich ascites cells

1984 • 33 citations

Deoxycytidylate shortage is a cause of G1 arrest of ascites tumor cells under oxygen deficiency

1983 • 30 citations

Oxygen dependent regulation of mammalian ribonucleotide reductase in vivo and possible significance for replicon initiation

1989 • 29 citations

Intracellular Compartmentation of Deoxycytidine Nucleotide Pools in S Phase Mouse 3T3 Fibroblasts

1989 • 27 citations

Reversible inhibition of replicon initiation in Ehrlich ascites cells by anaerobiosis

1980 • 27 citations

Selective and synchronous activation of early-S-phase replicons of Ehrlich ascites cells.

1993 • 24 citations

Deoxycytidine is salvaged not only into dna but also into phospholipid precursors

1988 • 22 citations

Chromosome band patterns of near tetraploid Ehrlich-Lettré mouse ascites cells (ELT Bonn) in vivo and in vitro

2008 • 22 citations

Reversible shutdown of replicon initiation by transient hypoxia in Ehrlich ascites cells

1992 • 20 citations

Ribonucleotide reductase in ascites tumour cells detected by electron paramagnetic resonance spectroscopy

1985 • 16 citations

DnaA-dependent Assembly of the ABC Primosome at the A Site, A Single-stranded DNA Hairpin Containing a DnaA Box

1995 • 16 citations

Synchronous replication of SV 40 DNA in virus infected TC 7 cells induced by transient hypoxia

1993 • 13 citations

Oxygen Dependent Regulation of DNA Replication of Ehrlich Ascites Cells In Vitro and In Vivo

1988 • 9 citations

Stability and reactivation of tyrosine radicals from ribonucleotide reductase in tumor cells studied by ESR

1989 • 7 citations

DnaA-dependent Assembly of the ABC Primosome at the A Site, A Single-stranded DNA Hairpin Containing a DnaA Box

1995 • 1 citations

Deleted Work

1955 • 0 citations