Intracellular Glycerol Levels Modulate the Activity of Sln1p, aSaccharomyces cerevisiae Two-component Regulator

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae.

1989 • 8,705 citations

Methods in Yeast Genetics

1988 • 4,905 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1984 • 4,899 citations

[12] One-step gene disruption in yeast

1983 • 3,302 citations

In Vivo Half-Life of a Protein Is a Function of Its Amino-Terminal Residue

1986 • 1,942 citations

A new efficient gene disruption cassette for repeated use in budding yeast

1996 • 1,609 citations

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1991 • 1,369 citations

An Osmosensing Signal Transduction Pathway in Yeast

1993 • 1,252 citations

A two-component system that regulates an osmosensing MAP kinase cascade in yeast

1994 • 1,091 citations

Construction of a set of convenient saccharomyces cerevisiae strains that are isogenic to S288C

1995 • 945 citations

Yeast HOG1 MAP Kinase Cascade Is Regulated by a Multistep Phosphorelay Mechanism in the SLN1–YPD1–SSK1 “Two-Component” Osmosensor

1996 • 876 citations

Signal transduction in bacteria

1990 • 683 citations

Activation of Yeast PBS2 MAPKK by MAPKKKs or by Binding of an SH3-Containing Osmosensor

1995 • 649 citations

GPD1, Which Encodes Glycerol-3-Phosphate Dehydrogenase, Is Essential for Growth under Osmotic Stress in Saccharomyces cerevisiae, and Its Expression Is Regulated by the High-Osmolarity Glycerol Response Pathway

1994 • 630 citations

Osmotic Activation of the HOG MAPK Pathway via Ste11p MAPKKK: Scaffold Role of Pbs2p MAPKK

1997 • 569 citations

Fusion of Escherichia coli lacZ to the cytochrome c gene of Saccharomyces cerevisiae.

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A mutant of Saccharomyces cerevisiae defective for nuclear fusion.

1976 • 530 citations

Two nuclear mutations that block mitochondrial protein import in yeast.

1984 • 490 citations

Stress tolerance: The key to effective strains of industrial baker's yeast

1997 • 451 citations

A Yeast Protein Similar to Bacterial Two-Component Regulators

1993 • 431 citations

A candidate protein kinase C gene, PKC1, is required for the S. cerevisiae cell cycle

1990 • 422 citations

Fps1, a yeast member of the MIP family of channel proteins, is a facilitator for glycerol uptake and efflux and is inactive under osmotic stress.

1995 • 418 citations

A Mechanosensitive Ion Channel in the Yeast Plasma Membrane

1988 • 382 citations

A yeast mitogen-activated protein kinase homolog (Mpk1p) mediates signalling by protein kinase C.

1993 • 373 citations

Biophysical Control of Plant Cell Growth

1986 • 372 citations

Mutants in the S. cerevisiae PKC1 gene display a cell cycle-specific osmotic stability defect.

1992 • 371 citations

Dominant Mutations in a Gene Encoding a Putative Protein Kinase (BCKT) Bypass the Requirement for a Saccharomyces cerevisiae Protein Kinase C Homolog

1992 • 322 citations

MKK1 and MKK2, Which Encode Saccharomyces cerevisiae Mitogen-Activated Protein Kinase-Kinase Homologs, Function in the Pathway Mediated by Protein Kinase C

1993 • 306 citations

Roles of glycerol and glycerol-3-phosphate dehydrogenase (NAD+) in acquired osmotolerance of Saccharomyces cerevisiae

1989 • 297 citations

Osmoregulation and glycerol metabolism in the yeastSaccharomyces cerevisiae

1997 • 295 citations

A Second Osmosensing Signal Transduction Pathway in Yeast

1995 • 278 citations

Osmotic stress and the yeast cytoskeleton: phenotype-specific suppression of an actin mutation.

1992 • 245 citations

A synthetic lethal screen identifies SLK1, a novel protein kinase homolog implicated in yeast cell morphogenesis and cell growth.

1992 • 235 citations

A protein kinase gene complements the lytic phenotype of Saccharomyces cerevisiae lyt2 mutants

1991 • 197 citations

Osmotic Balance Regulates Cell Fusion during Mating in Saccharomyces cerevisiae

1997 • 131 citations

A Yeast Mitogen-Activated Protein Kinase Homolog (Mpk1p) Mediates Signalling by Protein Kinase C

1993 • 126 citations

Osmostress response of the yeast Saccharomyces

1993 • 111 citations

Positioning of cell growth and division after osmotic stress requires a map kinase pathway

1994 • 100 citations

Characteristics of Fps1-dependent and -independent glycerol transport in Saccharomyces cerevisiae

1997 • 91 citations

A Synthetic Lethal Screen Identifies SLK1, a Novel Protein Kinase Homolog Implicated in Yeast Cell Morphogenesis and Cell Growth

1992 • 74 citations

A library of yeast genomic MCM1 binding sites contains genes involved in cell cycle control, cell wall and membrane structure, and metabolism

1994 • 74 citations

Passive Response ofSaccharomyces cerevisiaeto Osmotic Shifts: Cell Volume Variations Depending on the Physiological State

1996 • 71 citations

The hypo-osmolarity-sensitive phenotype of the Saccharomyces cerevisiae hpo2 mutant is due to a mutation in PKC1, which regulates expression of β-glucanase

1994 • 63 citations

Translation and stability of anEscherichia coliβ-galactosidase mRNA expressed under the control of pyruvate kinase sequences inSaccharomyces cerevisiae

1987 • 51 citations

Saccharomyces cerevisiae actin-Escherichia coli lacZ gene fusions: Synthetic-oligonucleotide-mediated deletion of the 309 base pair intervening sequence in the actin gene

1983 • 51 citations

In vivo creep and stress relaxation experiments to determine the wall extensibility and yield threshold for the sporangiophores of phycomyces

1989 • 50 citations

Activated Alleles of Yeast SLN1 Increase Mcm1-dependent Reporter Gene Expression and Diminish Signaling through the Hog1 Osmosensing Pathway

1997 • 46 citations

The Essential Transcription Factor, Mcm1, Is a Downstream Target of Sln1, a Yeast "Two-component" Regulator

1995 • 38 citations

SPT13 (GAL11) of Saccharomyces cerevisiae Negatively Regulates Activity of the MCM1 Transcription Factor in Ty1 Elements

1993 • 38 citations

Isolation and Analysis of the Yeast TEA1 Gene, Which Encodes a Zinc Cluster Ty Enhancer-Binding Protein

1996 • 31 citations

The Osmotic Hypersensitivity of the YeastSaccharomyces cerevisiae is Strain and Growth Media Dependent: Quantitative Aspects of the Phenomenon

1997 • 31 citations

The effects of alterations within the 3' untranslated region of the pyruvate kinase messenger RNA upon its stability and translation inSaccharomyces cerevisiae

1987 • 23 citations