Cellular localization of the endothelin receptor subtypes ET A and ET B in the rat heart and their differential expression in coronary arteries, veins, and capillaries

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

A novel potent vasoconstrictor peptide produced by vascular endothelial cells

1988 • 10,786 citations

Endothelins: molecular biology, biochemistry, pharmacology, physiology, and pathophysiology.

1994 • 1,631 citations

Inhibition of myocardial endothelin pathway improves long-term survival in heart failure

1996 • 630 citations

Cholinergic neurons and terminal fields revealed by immunohistochemistry for the vesicular acetylcholine transporter. I. Central nervous system

1998 • 324 citations

Effects of endothelins on collagen turnover in cardiac fibroblasts

1993 • 290 citations

Endogenous Endothelin-1 Participates in the Maintenance of Cardiac Function in Rats With Congestive Heart Failure

1996 • 287 citations

Distinct tissue distribution and cellular localization of two messenger ribonucleic acids encoding different subtypes of rat endothelin receptors.

1992 • 273 citations

Molecular and functional characterization of the non-isopeptide-selective ETB receptor in endothelial cells. Receptor coupling to nitric oxide synthase.

1994 • 227 citations

Antibodies defining rat endothelial cells: RECA-1, a pan-endothelial cell-specific monoclonal antibody.

1992 • 209 citations

Endothelin‐1, phorbol esters and phenylephrine stimulate MAP kinase activities in ventricular cardiomyocytes

1993 • 179 citations

An Optimized Method for In Situ Hybridization with Signal Amplification That Allows the Detection of Rare mRNAs

1999 • 177 citations

Endothelin ET_A and ET_B mRNA and receptors expressed by smooth muscle in the human vasculature: majority of the ET_A sub‐type

1995 • 160 citations

The right auricle of the heart is an endocrine organ

1983 • 138 citations

Endothelin‐1 enhances neutrophil adhesion to human coronary artery endothelial cells: role of ET_A receptors and platelet‐activating factor

1999 • 126 citations

Endothelin-1 Stimulates Cardiac Fibroblast Proliferation Through Activation of Protein Kinase C

2000 • 125 citations

Proliferation and migration of endothelial cells is promoted by endothelins via activation of ETB receptors

1995 • 121 citations

Autoradiographic Localization of Endothelin-1 Binding Sites in the Cardiovascular and Respiratory Systems

1989 • 115 citations

Increased immunoreactivity of endothelin-1 and endothelin B receptor in human atherosclerotic lesions. A possible role in atherogenesis

1999 • 106 citations

Palmitoylation of Endothelin Receptor A

1996 • 103 citations

Identification of G protein-coupled signaling pathways in cardiac fibroblasts: cross talk between G_qand G_s

2000 • 102 citations

Pharmacology of a non‐selective ET_A and ET_B receptor antagonist, TAK‐044 and the inhibition of myocardial infarct size in rats

1995 • 91 citations

Endothelin receptors in cultured adult rat cardiac fibroblasts

1993 • 90 citations

Endothelin stimulates atrial natriuretic peptide (ANP) release from rat atria

1988 • 87 citations

Evidence for the existence of endothelin-B receptor subtypes and their physiological roles in the rat

1996 • 80 citations

Ischemia-Reperfusion Injury at the Microvascular Level

2000 • 77 citations

Endothelin Stimulates Basal and Stretch-Induced Atrial Natriuretic Peptide Secretion from the Perfused Rat Heart*

1990 • 71 citations

Growth properties and biochemical characterization of collagens synthesized by adult rat heart fibroblasts in culture

1992 • 68 citations

Microvascular Endothelial Cells from Heart

1990 • 62 citations

Chronic Oral Endothelin Type A Receptor Antagonism in Experimental Heart Failure

1998 • 61 citations

NADPH oxidase subunits and superoxide production in porcine pulmonary artery endothelial cells

2000 • 58 citations

Binding Sites for Endothelin-1 in Rat Tissues

1989 • 57 citations

Detection of Endothelin Receptors in Human Coronary Artery Vascular Smooth Muscle Cells But Not Endothelial Cells by Using Electron Microscope Autoradiography

1997 • 49 citations

Beneficial effects of the endothelin receptor antagonist bosentan on myocardial and endothelial injury following ischaemia/reperfusion in the rat

1995 • 47 citations

Endothelin-1 causes P-selectin-dependent leukocyte rolling and adhesion within rat mesenteric microvessels

1999 • 46 citations

Endothelin-A and -B antagonists protect myocardial and endothelial function after ischemia/reperfusion in a rat heart transplantation model

1998 • 40 citations

Coronary vasoconstriction to endothelin-1 increases with age before and after ischaemia and reperfusion

1999 • 37 citations

The endothelin A receptor antagonist LU 135252 protects the myocardium from neutrophil injury during ischaemia/reperfusion

1998 • 36 citations

Nitric oxide and endothelin in the development of cardiac allograft vasculopathy. Potential targets for therapeutic interventions

1998 • 35 citations

Characterization of endothelin-1-induced vascular effects in the rat heart by using endothelin receptor antagonists

1994 • 34 citations

Contribution of endothelin to the coronary vasoconstriction in the isolated rat heart induced by nitric oxide synthase inhibition

1998 • 28 citations

Endothelin B receptor-mediated vasoconstriction induced by endothelin A receptor antagonist

1998 • 22 citations

Synthesis of Digoxigenin-Labeled cRNA Probes for Nonisotopic in Situ Hybridization Using Reverse Transcription Polymerase Chain Reaction

1993 • 20 citations

Endothelins: potent releasers of prostacyclin and EDRF.

1990 • 19 citations

Functional Role for Glycosylated Subtypes of Rat Endothelin Receptors

1998 • 17 citations

Effects of calcium antagonists on endothelin‐1‐induced myocardial ischaemia and oedema in the rat

1996 • 14 citations

Endothelin-A Receptor in Rat Skeletal Muscle Microvasculature

2002 • 13 citations

Synthesis and receptor sites of endothelin-1 in the rat liver vasculature

2000 • 11 citations

Endothelin Antagonists Diminish Postischemic Microvascular Incompetence and Necrosis in the Heart

2000 • 11 citations

A Nonradioactive Method for Localization of Endothelin Receptor mRNA In Situ

1998 • 6 citations

PD 142893, SB 209670, and BQ 788 Selectively Antagonize Vascular Endothelial Versus Vascular Smooth Muscle ETB-Receptor Activity in the Rat

1998 • 5 citations