IV glycine and oral d-cycloserine effects on plasma and CSF amino acids in healthy humans

“Mini-mental state”

1975 • 82,784 citations

The Pharmacological Basis of Therapeutics

1976 • 8,675 citations

Computational analysis of present-day American English

1967 • 7,607 citations

Glycine potentiates the NMDA response in cultured mouse brain neurons

1987 • 3,116 citations

Requirement for Glycine in Activation of NMDA-Receptors Expressed in Xenopus Oocytes

1988 • 1,415 citations

Word fluency and brain damage

1967 • 1,284 citations

The hopkins verbal learning test: Development of a new memory test with six equivalent forms

1991 • 1,237 citations

The neurological evaluation scale (NES): A structured instrument for the assessment of neurological signs in schizophrenia

1989 • 572 citations

Efficacy of High-Dose Glycine in the Treatment of Enduring Negative Symptoms of Schizophrenia

1999 • 484 citations

The glycine site of the NMDA receptor — five years on

1993 • 440 citations

A Placebo-Controlled Trial of D-Cycloserine Added to Conventional Neuroleptics in Patients With Schizophrenia

1999 • 435 citations

In vivo determination of extracellular concentration of amino acids in the rat hippocampus. A method based on brain dialysis and computerized analysis

1986 • 428 citations

Cloning and expression of a glycine transporter reveal colocalization with NMDA receptors

1992 • 428 citations

Amelioration of negative symptoms in schizophrenia by glycine

1994 • 349 citations

Startle gating deficits occur across prepulse intensities in schizophrenic patients

1992 • 332 citations

d-Cycloserine: A ligand for the coupled glycine receptor has partial agonist characteristics

1989 • 302 citations

Comparative Effect of Transient Global Ischemia on Extracellular Levels of Glutamate, Glycine, and γ‐Aminobutyric Acid in Vulnerable and Nonvulnerable Brain Regions in the Rat

1991 • 299 citations

Double-Blind, Placebo-Controlled, Crossover Trial of Glycine Adjuvant Therapy for Treatment-Resistant Schizophrenia

1996 • 253 citations

Antagonism of phencyclidine-induced deficits in prepulse inhibition by the putative atypical antipsychotic olanzapine

1995 • 194 citations

Two glycine transporter variants with distinct localization in the CNS and peripheral tissues are encoded by a common gene

1993 • 194 citations

Glycine is a coagonist at the NMDA receptor/channel complex

1990 • 172 citations

Structural requirements for activation of the glycine coagonist site of N-methyl-D-aspartate receptors expressed in Xenopus oocytes.

1989 • 159 citations

Intracerebral Microdialysis of Extracellular Amino Acids in the Human Epileptic Focus

1992 • 147 citations

Modulation of excitatory synaptic transmission by glycine and zinc in cultures of mouse hippocampal neurons

1988 • 146 citations

Competitive antagonists and partial agonists at the glycine modulatory site of the mouse N‐methyl‐D‐aspartate receptor.

1990 • 139 citations

Serine Hydroxymethyltransferase

1982 • 116 citations

Characterization df a [³H]Glycine Recognition Site as a Modulatory Site of the N‐Methyl‐D‐Aspartate Receptor Complex

1989 • 106 citations

Actions of ?-cycloserine at the ? glycine receptor site in vivo

1991 • 105 citations

Evidence of acoustic startle hyperreflexia in recently detoxified early onset male alcoholics: modulation by yohimbine and m -Chlorophenylpiperazine (mCPP)

1997 • 95 citations

Preliminary investigation of high-dose oral glycine on serum levels and negative symptoms in schizophrenia: an open-label trial

1996 • 91 citations

The Origin and Turnover of D-Serine in Brain

1997 • 89 citations

EVIDENCE FOR SEPARATE SYSTEMS FOR THE TRANSPORT OF NEUTRAL AND BASIC AMINO ACIDS ACROSS THE BLOOD‐BRAIN BARRIER

1971 • 84 citations

Effects of the PCP analog dizocilpine on sensory gating: Potential relevance to clinical subtypes of schizophrenia

1996 • 77 citations

Pharmacological characteristics of cyclic homologues of glycine at the N-methyl-d-aspartate receptor-associated glycine site

1990 • 76 citations

SEROTONIN AND DOPAMINE METABOLITES IN BRAIN REGIONS AND CEREBROSPINAL FLUID OF A PRIMATE SPECIES: EFFECTS OF KETAMINE AND FLUPHENAZINE

1979 • 75 citations

Reversal of Phencyclidine-Induced Hyperactivity by Glycine and the Glycine Uptake Inhibitor Glycyldodecylamide

1997 • 74 citations

In Vivo Evidence for the Link Between <scp>l</scp>‐ and <scp>d</scp>‐Serine Metabolism in Rat Cerebral Cortex

1997 • 73 citations

Glycyldodecylamide, a phencyclidine behavioral antagonist, blocks cortical glycine uptake: implications for schizophrenia and substance abuse

1997 • 70 citations

Glycine Site Agonists of the NMDA Receptor: A Review

1995 • 57 citations

Depletion of Cerebral D-Serine in Non-Ketotic Hyperglycinemia: Possible Involvement of Glycine Cleavage System in Control of Endogenous D-Serine

1997 • 56 citations

The glycine/NMDA receptor antagonist, L-701,324 reverses isolation-induced deficits in prepulse inhibition in the rat

1995 • 55 citations

Glycinergic augmentation of NMDA receptor-mediated neurotransmission in the treatment of schizophrenia.

1996 • 53 citations

Effect of the glycine/NMDA receptor partial agonist, D-cycloserine, on seizure threshold and some pharmacodynamic effects of MK-801 in mice

1994 • 45 citations

The Treatment of Isovaleric Acidemia with Glycine Supplement

1988 • 43 citations

Absorption, distribution, and excretion of cycloserine in man.

1955 • 43 citations

Neutral amino acid uptake by the isolated perfused sheep choroid plexus.

1989 • 42 citations

Cerebrospinal Fluid Pharmacokinetics of the Antituberculosis Drugs

1985 • 36 citations

Therapeutic trial with glycine in myoclonus

1988 • 33 citations

Pathways of Serine and Glycine Metabolism in Primary Culture of Ovine Fetal Hepatocytes

1995 • 28 citations

Competitive NMDA and Strychnine-Insensitive Glycine-Site Antagonists Disrupt Prepulse Inhibition

1997 • 20 citations

Glycine ketamine interactions in healthy humans

1997 • 18 citations

Glycine stimulates growth hormone release in man

1980 • 15 citations

Decarboxylation of glycine by serine hydroxymethyltransferase in the presence of lipoic acid.

1983 • 15 citations

A current appraisal of cycloserine.

1957 • 15 citations

�ber die Verteilung und Stoffwechsel des Cycloserins bei der Ratte

1960 • 13 citations

Glycine transport inhibitors: A new class of antipsychotics?

1997 • 2 citations

Growth hormone release by glycine injected intravenously in 22 healthy sexually immature children.

1975 • 1 citations