Back to search

Effect of the glycine/NMDA receptor partial agonist, D-cycloserine, on seizure threshold and some pharmacodynamic effects of MK-801 in mice

Data up to Jan 2025

Published1994
Citations45
References47

Total Citations Per Year

Abstract

References (47)

A simplified method of evaluating dose-effect experiments.

1948 • 7,047 citations

A Note on a Simple Apparatus for Detecting Neurological Deficit in Rats and Mice**College of Pharmacy, University of Nebraska, Lincoln 8.

1957 • 1,671 citations

Basic Mechanisms of the Epilepsies.

1970 • 1,131 citations

Cooperative Modulation of [3H]MK‐801 Binding to the N‐Methyl‐d‐Aspartate Receptor‐Ion Channel Complex by l‐Glutamate, Glycine, and Polyamines

1988 • 755 citations

The glycine site of the NMDA receptor — five years on

1993 • 440 citations

The NMDA Receptor

1995 • 356 citations

The role of technical, biological and pharmacological factors in the laboratory evaluation of anticonvulsant drugs. II. Maximal electroshock seizure models

1991 • 341 citations

3H-labeled MK-801 binding to the excitatory amino acid receptor complex from rat brain is enhanced by glycine.

1987 • 335 citations

The behavioral pharmacology of NMDA receptor antagonists

1990 • 331 citations

d-Cycloserine: A ligand for the coupled glycine receptor has partial agonist characteristics

1989 • 302 citations

D-cycloserine, a positive modulator of the N-methyl-D-aspartate receptor, enhances performance of learning tasks in rats

1989 • 253 citations

Adaptive changes in the N-methyl-D-aspartate receptor complex after chronic treatment with imipramine and 1-aminocyclopropanecarboxylic acid.

1993 • 192 citations

Chemical Protection against Ionizing Radiation: I. Sampling Methods for Screening Compounds in Radiation Protection Studies with Mice

1957 • 186 citations

Basic mechanisms of the epilepsies: Molecular and cellular approaches

1987 • 186 citations

d-Cycloserine acts as a partial agonist at the glycine modulatory site of the NMDA receptor expressed inXenopus oocytes

1990 • 168 citations

Effect on memory processing by D-cycloserine, an agonist of the NMDA/glycine receptor

1992 • 154 citations

Competitive antagonists and partial agonists at the glycine modulatory site of the mouse N‐methyl‐D‐aspartate receptor.

1990 • 139 citations

Modulation of glutamate receptors by phencyclidine and glycine in the rat cerebellum: cGMP increase in vivo

1989 • 122 citations

Actions of ?-cycloserine at the ? glycine receptor site in vivo

1991 • 105 citations

In Vivo Modulation of the N‐Methyl‐D‐Aspartate Receptor Complex by D‐Serine: Potentiation of Ongoing Neuronal Activity as Evidenced by Increased Cerebellar Cyclic GMP

1989 • 100 citations

D-Cycloserine reverses the working memory impairment of hippocampal-lesioned rats in a spatial learning task

1992 • 94 citations

Evaluation of CPP, a selective NMDA antagonist, in various rodent models of epilepsy. Comparison with other NMDA antagonists, and with diazepam and phenobarbital

1988 • 84 citations

Chronic treatment with 1-aminocyclopropanecarboxylic acid desensitizes behavioral responses to compounds acting at the N-methyl-d-aspartate receptor complex

1992 • 79 citations

A novel treatment of global cerebral ischaemia with a glycine partial agonist

1992 • 65 citations

d-Cycloserine, a modulator of the receptor, improves spatial learning in rats treated with muscarinic antagonist

1992 • 64 citations

Transmitter amino acid levels in rat brain regions after amygdala-kindling or chronic electrode implantation without kindling: Evidence for a pro-kindling effect of prolonged electrode implantation

1993 • 54 citations

Effect of glutamate receptor antagonists on N-methyl-D-aspartate- and (S)-α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid-induced convulsant effects in mice and rats

1993 • 50 citations

Anticataleptic potencies of glutamate-antagonists

1991 • 41 citations

Influence of MK-801 on the anticonvulsant activity of antiepileptics

1991 • 39 citations

Subtypes of NMDA receptors

1993 • 38 citations

Development of tolerance to the anticonvulsant effect of vigabatrin in amygdala-kindled rats

1992 • 37 citations

Interactions Between the Glutamate and Glycine Recognition Sites of the N‐Methyl‐<scp>d</scp>‐Aspartate Receptor from Rat Brain, as Revealed from Radioligand Binding Studies

1993 • 37 citations

The NMDA positive modulatord-cycloserine potentiates the neuroleptic activity of D1 and D2 dopamine receptor blockers in the rat

1993 • 32 citations

The Role of Cyclic Nucleotides in the Nervous System

1982 • 31 citations

The anticonvulsant activity of d-cycloserine is specific for tonic convulsions

1993 • 30 citations

7-Chlorokynurenic acid antagonizes the anticonvulsant activity of d-cycloserine in maximal electroshock seizures

1992 • 28 citations

Mode of Action, Biotransformation and Pharmacokinetics of Antituberculosis Drugs in Animals and Man

1988 • 27 citations

Comparison of pharmacodynamic effects of the non-competitive NMDA receptor antagonists MK-801 and ketamine in pigs

1991 • 23 citations

Roles of biogenic amines and cyclic nucleotides in seizure mechanisms.

1986 • 21 citations

[On the inhibition of L-glutamic acid and L-DOPA decarboxylase by D-cycloserine and other isoxazolidones].

1962 • 17 citations

Glycinergic interventions potentiate the ability of MK 801 to raise the threshold voltage for tonic hindlimb extension in mice

1992 • 17 citations

Zur Hemmung der L-Glutamins�ure-und L-Dopadecarboxylase durch D-Cycloserin und andere Isoxazolidone

1962 • 15 citations

A current appraisal of cycloserine.

1957 • 15 citations

Anti-tuberculosis drugs

1989 • 14 citations

�ber die Verteilung und Stoffwechsel des Cycloserins bei der Ratte

1960 • 13 citations

Historical Introduction and Chemical Characteristics of Antituberculosis Drugs

1988 • 10 citations

Experimental Pharmacology and Toxicology of Antituberculosis Drugs

1988 • 5 citations

Cited By (0)

Loading...