Long-term administration of green tea catechins prevents age-related spatial learning and memory decline in C57BL/6 J mice by regulating hippocampal cyclic amp-response element binding protein signaling cascade

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1999 • 2,076 citations

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2002 • 2,037 citations

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2001 • 1,926 citations

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1994 • 1,802 citations

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1998 • 1,504 citations

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2005 • 1,155 citations

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1999 • 794 citations

Emerging role of polyphenolic compounds in the treatment of neurodegenerative diseases: A review of their intracellular targets

2006 • 675 citations

Effects of brain-derived neurotrophic factor on optic axon branching and remodelling in vivo

1995 • 583 citations

Age-related defects in spatial memory are correlated with defects in the late phase of hippocampal long-term potentiation in vitro and are attenuated by drugs that enhance the cAMP signaling pathway

1999 • 561 citations

The Mitogen-Activated Protein Kinase Cascade Couples PKA and PKC to cAMP Response Element Binding Protein Phosphorylation in Area CA1 of Hippocampus

1999 • 542 citations

Involvement of Brain-Derived Neurotrophic Factor in Spatial Memory Formation and Maintenance in a Radial Arm Maze Test in Rats

2000 • 539 citations

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2006 • 443 citations

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2004 • 439 citations

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2006 • 407 citations

BDNF Regulates the Translation of a Select Group of mRNAs by a Mammalian Target of Rapamycin-Phosphatidylinositol 3-Kinase-Dependent Pathway during Neuronal Development

2004 • 399 citations

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2002 • 360 citations

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2004 • 356 citations

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2004 • 318 citations

Oral Consumption of Green Tea Polyphenols Inhibits Insulin-Like Growth Factor-I–Induced Signaling in an Autochthonous Mouse Model of Prostate Cancer

2004 • 296 citations

Flavonoid fisetin promotes ERK-dependent long-term potentiation and enhances memory

2006 • 295 citations

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2007 • 287 citations

Green tea catechins as brain‐permeable, natural iron chelators‐antioxidants for the treatment of neurodegenerative disorders

2006 • 280 citations

Brain-derived neurotrophic factor, phosphorylated cyclic AMP response element binding protein and neuropeptide Y decline as early as middle age in the dentate gyrus and CA1 and CA3 subfields of the hippocampus

2005 • 225 citations

Long-Term Administration of Green Tea Catechins Improves Spatial Cognition Learning Ability in Rats

2006 • 224 citations

Hippocampal neuron and synaptophysin-positive bouton number in aging C57BL/6 mice

1998 • 218 citations

CREB phosphorylation as a molecular marker of memory processing in the hippocampus for spatial learning

2002 • 210 citations

Reduction in Size of Perforated Postsynaptic Densities in Hippocampal Axospinous Synapses and Age-Related Spatial Learning Impairments

2004 • 195 citations

(‐)Epicatechin stimulates ERK‐dependent cyclic AMP response element activity and up‐regulates GluR2 in cortical neurons

2007 • 172 citations

Purple sweet potato color repairs d-galactose-induced spatial learning and memory impairment by regulating the expression of synaptic proteins

2008 • 162 citations

Iron dysregulation in Alzheimer's disease: Multimodal brain permeable iron chelating drugs, possessing neuroprotective-neurorescue and amyloid precursor protein-processing regulatory activities as therapeutic agents

2007 • 160 citations

Re-establishing the regenerative potential of central nervous system axons in postnatal mice

2005 • 156 citations

Green tea polyphenol (–)‐epigallocatechin‐3‐gallate induces neurorescue of long‐term serum‐deprived PC12 cells and promotes neurite outgrowth

2005 • 146 citations

Caffeine prevents age-associated recognition memory decline and changes brain-derived neurotrophic factor and tirosine kinase receptor (TrkB) content in mice

2008 • 117 citations

The in vivo synaptic plasticity mechanism of EGb 761‐induced enhancement of spatial learning and memory in aged rats

2006 • 103 citations

Bcl-2 enhances Ca2+ signaling to support the intrinsic regenerative capacity of CNS axons

2005 • 102 citations

Acute and long-term synaptic modulation by neurotrophins

2004 • 101 citations

Hippocampal CREB1 but not CREB2 is decreased in aged rats with spatial memory impairments

2003 • 85 citations

Alteration of CREB phosphorylation and spatial memory deficits in aged 129T2/Sv mice

2007 • 82 citations

Age-related disturbance of memory and CREB phosphorylation in CA1 area of hippocampus of rats

2005 • 73 citations

Differential expression of PSD proteins in age-related spatial learning impairments

2005 • 70 citations

Alterations in the balance of protein kinase and phosphatase activities and age‐related impairments of synaptic transmission and long‐term potentiation

2002 • 64 citations

Annurca apple-rich diet restores long-term potentiation and induces behavioral modifications in aged rats

2006 • 49 citations

Protein synthesis in entorhinal cortex and long-term potentiation in dentate gyrus

2000 • 41 citations