Bupropion: A new antidepressant drug, the mechanism of action of which is not associated with down-regulation of postsynaptic β-adrenergic, serotonergic (5-HT2), α2-adrenergic, imipramine and dopaminergic receptors in brain

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

A highly sensitive adenylate cyclase assay

1974 • 4,213 citations

Benzodiazepine receptors in rat brain

1977 • 1,459 citations

Multiple serotonin receptors: differential binding of [3H]5-hydroxytryptamine, [3H]lysergic acid diethylamide and [3H]spiroperidol.

1979 • 1,321 citations

Muscarinic Cholinergic Binding in Rat Brain

1974 • 1,214 citations

Properties of γ-aminobutyric acid (GABA) receptor binding in rat brain synaptic membrane fractions

1975 • 637 citations

Action of various antidepressant treatments reduces reactivity of noradrenergic cyclic AMP-generating system in limbic forebrain

1975 • 599 citations

Beta adrenergic receptor binding in membrane preparations from mammalian brain.

1976 • 576 citations

Adenosine receptors in brain membranes: binding of N6-cyclohexyl[3H]adenosine and 1,3-diethyl-8-[3H]phenylxanthine.

1980 • 554 citations

Mode of action of antidepressant drugs

1978 • 514 citations

Properties of [3H]haloperidol and [3H]dopamine binding associated with dopamine receptors in calf brain membranes.

1976 • 480 citations

A RADIOISOTOPIC METHOD FOR MEASURING THE FORMATION OF ADENOSINE 3′,5′‐CYCLIC MONOPHOSPHATE IN INCUBATED SLICES OF BRAIN

1969 • 471 citations

Presynaptic modulation of beta adrenergic receptors in rat cerebral cortex after treatment with antidepressants.

1978 • 440 citations

Alpha-noradrenergic receptor binding in mammalian brain: Differential labeling of agonist and antagonist states

1976 • 298 citations

Specific tricyclic antidepressant binding sites in rat brain

1979 • 266 citations

Direct identification and characterisation of β-adrenergic receptors in rat brain

1975 • 246 citations

Behavioral and biochemical effects of the antidepressant bupropion (Wellbutrin): evidence for selective blockade of dopamine uptake in vivo.

1980 • 203 citations

The effect of psychoactive drugs on beta-adrenergic receptor binding sites in rat brain

1980 • 188 citations

Serotonin receptor sensitivity after acute and chronic treatment with mianserin.

1982 • 188 citations

Characterization of the adrenergic receptors mediating a rise in cyclic 3'-5'-adenosine monophosphate in rat cerebral cortex.

1973 • 184 citations

Action of mianserin and zimelidine on the norepinephrine receptor coupled adenylate cyclase system in brain: Subsensitivity without reduction in β-adrenergic receptor binding

1980 • 178 citations

Desmethylimipramine-induced decrease in β-adrenergic receptor binding in rat cerebral cortex

1978 • 141 citations

The Glycine Synaptic Receptor: Evidence That Strychnine Binding Is Associated with the Ionic Conductance Mechanism

1974 • 136 citations

Functional Aspects of the Norepinephrine Receptor Coupled Adenylate Cyclase System in the Limbic Forebrain and its Modification by Drugs which Precipitate or Alleviate Depression: Molecular Approaches to an Understanding of Affective Disorders

1978 • 132 citations

Acceleration of β-receptor desensitization in combined administration of antidepressants and phenoxybenzamine

1981 • 118 citations

Bupropion hydrochloride ((±) α-t-butylamino-3-chloropropiophenone HCl): a novel antidepressant agent

1977 • 116 citations

Effects of 6-hydroxydopamine on the development of the beta adrenergic receptor/adenylate cyclase system in rat cerebral cortex.

1977 • 86 citations

Some neurochemical properties of a new antidepressant, bupropion hydrochloride (Wellbutrin™)

1981 • 66 citations

Neurochemical and neuropharmacological investigations into the mechanisms of action of bupropion . HCl--a new atypical antidepressant agent.

1982 • 30 citations

Role of beta‐adrenergic receptors in the mechanism of action of second‐generation antidepressants

1982 • 16 citations

Deleted Work

1955 • 0 citations