The metabolic disposition of flucloxacillin in patients with impaired kidney function

Clinical pharmacology of the new penicillins: I. The importance of serum protein binding in determining antimicrobial activity and concentration in serum

1966 • 142 citations

Diseases and Drug Protein Binding

1978 • 132 citations

Metabolism of Penicillins to Penicilloic Acids and 6-Aminopenicillanic Acid in Man and Its Significance in Assessing Penicillin Absorption

1973 • 128 citations

The biotransformation of drugs in renal failure

1977 • 122 citations

Pharmacokinetics of the Penicillins in Man

1976 • 116 citations

Renal Failure, Drug Pharmacokinetics and Drug Action

1976 • 110 citations

Apparent volumes of distribution and drug binding to plasma proteins and tissues

1978 • 102 citations

Pharmacologically Active Drug Metabolites

1976 • 92 citations

Alteration of plasma albumin in relation to decreased drug binding in uremia

1977 • 90 citations

Pharmacokinetic concepts ? Drug binding, apparent volume of distribution and clearance

1981 • 90 citations

The Binding of Drugs to Plasma Proteins from Patients with Poor Renal Function

1976 • 75 citations

Pharmacokinetics of flucloxacillin and cloxacillin in healthy subjects and patients on chronic intermittent haemodialysis.

1975 • 59 citations

Elimination Kinetics and Dosage Adjustment of Drugs in Patients with Kidney Disease

1978 • 58 citations

Levels of Carbenicillin, Ticarcillin, Cephalothin, Cefazolin, Cefamandole, Gentamicin, Tobramycin, and Amikacin in Human Serum and Interstitial Fluid

1977 • 56 citations

Inhibition of Sporulation by Cerulenin and Its Reversion by Exogenous Fatty Acids in Saccharomyces cerevisiae

1976 • 50 citations

Analysis of isoxazolyl penicillins and their metabolites in body fluids by high-performance liquid chromatography

1980 • 45 citations

Dicloxacillin and cloxacillin: Pharmacokinetics in healthy and hemodialysis subjects

1976 • 41 citations

Active Metabolites of Isoxazolylpenicillins in Humans

1976 • 35 citations

Pharmacokinetics of Cloxacillin in Patients on Chronic Intermittent Haemodialysis and in Healthy Subjects

1973 • 26 citations

Effects of Renal Disease upon Drug Disposition

1978 • 24 citations

Differences in Kinetic Properties of Drugs

1980 • 19 citations

Prediction of the Concentration of Penicillins in Ascitic Fluid from Serum Kinetics and Protein Binding of the Antibiotics in Serum and Ascitic Fluid of Dogs

1978 • 18 citations

Comparative Penetration of Various Cephalosporins into Inflammatory Exudate

1979 • 9 citations

Fate of oral35S-cloxacillin in man

1974 • 9 citations

Design of Penicillins

1971 • 5 citations

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