Troglitazone Increases System A Amino Acid Transport in 3T3-L1 Cells

An Antidiabetic Thiazolidinedione Is a High Affinity Ligand for Peroxisome Proliferator-activated Receptor γ (PPARγ)

1995 • 3,603 citations

PPARalpha and PPARgamma activators direct a distinct tissue-specific transcriptional response via a PPRE in the lipoprotein lipase gene.

1996 • 1,169 citations

Thiazolidinediones in the Treatment of Insulin Resistance and Type II Diabetes

1996 • 1,004 citations

Terminal differentiation of human liposarcoma cells induced by ligands for peroxisome proliferator-activated receptor γ and the retinoid X receptor

1997 • 655 citations

The Structure−Activity Relationship between Peroxisome Proliferator-Activated Receptor γ Agonism and the Antihyperglycemic Activity of Thiazolidinediones

1996 • 638 citations

The regulation of neutral amino acid transport in mammalian cells

1983 • 459 citations

Thiazolidinediones produce a conformational change in peroxisomal proliferator-activated receptor-gamma: binding and activation correlate with antidiabetic actions in db/db mice.

1996 • 378 citations

Regulatory and molecular aspects of mammalian amino acid transport

1994 • 368 citations

Thiazolidinediones repress ob gene expression in rodents via activation of peroxisome proliferator-activated receptor gamma.

1996 • 362 citations

Antidiabetic thiazolidinediones inhibit leptin (ob) gene expression in 3T3-L1 adipocytes.

1996 • 342 citations

Peroxisome proliferator-activated receptor-gamma activation by thiazolidinediones induces adipogenesis in bone marrow stromal cells.

1996 • 288 citations

Functional Antagonism between CCAAT/Enhancer Binding Protein-α and Peroxisome Proliferator-activated Receptor-γ on the Leptin Promoter

1997 • 250 citations

Plasma Amino Acid Levels in Diabetic Ketoacidosis

1970 • 248 citations

A Human Peroxisome‐Proliferator‐Activated Receptor‐γ is Activated by Inducers of Adipogenesis, Including Thiazolidinedione Drugs

1996 • 202 citations

Troglitazone enhances differentiation, basal glucose uptake, and Glut1 protein levels in 3T3-L1 adipocytes.

1996 • 159 citations

Activation of the Nuclear Receptor Peroxisome Proliferator-activated Receptor γ Promotes Brown Adipocyte Differentiation

1996 • 158 citations

Repeat Treatment of Obese Mice With BRL 49653, a New Potent Insulin Sensitizer, Enhances Insulin Action in White Adipocytes: Association With Increased Insulin Binding and Cell-Surface GLUT4 as Measured by Photoaffinity Labeling

1995 • 139 citations

Mechanisms of Transport of Amino Acids Across Membranes

1987 • 127 citations

Interorgan metabolism of amino acids in streptozotocin-diabetic ketoacidotic rat

1983 • 117 citations

Troglitazone prevents the inhibitory effects of inflammatory cytokines on insulin-induced adipocyte differentiation in 3T3-L1 cells.

1994 • 109 citations

Thiazolidine Derivatives Ameliorate High Glucose-induced Insulin Resistance via the Normalization of Protein-tyrosine Phosphatase Activities

1995 • 85 citations

The antidiabetic agent pioglitazone increases expression of glucose transporters in 3T3-F442A cells by increasing messenger ribonucleic acid transcript stability.

1993 • 84 citations

The Thiazolidinedione Insulin Sensitiser, BRL 49653, Increases the Expression of PPAR-γ and aP2in Adipose Tissue of High-Fat-Fed Rats

1996 • 76 citations

Regulation of glucose transport in cultured muscle cells by novel hypoglycemic agents

1995 • 72 citations

Acute and chronic effects of troglitazone (CS-045) on isolated rat ventricular cardiomyocytes

1996 • 71 citations

Pancreatic Diabetes Mellitus

1989 • 61 citations

Glutamine transport in cerebellar granule cells in culture

1997 • 59 citations

Glutamine and Alanine Metabolism in NIDDM

1996 • 56 citations

Regulation of glucose transport by pioglitazone in cultured muscle cells

1994 • 52 citations

Branched-chain amino acids and alanine as indices of the metabolic control in Type 1 (insulin-dependent) and Type 2 (non-insulin-dependent) diabetic patients

1982 • 39 citations

Regulation of System A Amino Acid Transport in 3T3-L1 Adipocytes by Insulin

1998 • 33 citations

Increased Plasma Gluconeogenic and System A Amino Acids in Patients with Pancreatic Diabetes due to Chronic Pancreatitis in Comparison with Primary Diabetes.

1994 • 5 citations