Ethylglyoxal bis(guanylhydrazone) as an inhibitor of polyamine biosynthesis in L1210 leukemia cells

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

An Improved Diphenylamine Method for the Estimation of Deoxyribonucleic Acid

1965 • 1,968 citations

On the Purification of l-Ornithine Decarboxylase from Rat Prostate and Effects of Thiol Compounds on the Enzyme

1971 • 462 citations

Polyamines in Biology and Medicine

1982 • 446 citations

On the Role of S-Adenosyl-L-methionine in the Biosynthesis of Spermidine by Rat Prostate

1969 • 415 citations

Use of the Dansyl Reaction in Biochemical Analysis

1970 • 373 citations

Methyl glyoxal bis(guanylhydrazone) as a potent inhibitor of mammalian and yeast S-adenosylmethionine decarboxylases

1972 • 344 citations

Intracellular putrescine and spermidine deprivation induces increased uptake of the natural polyamines and methylglyoxal bis(guanylhydrazone)

1980 • 182 citations

Specific inhibition of the enzymic decarboxylation of S-adenosylmethionine by methylglyoxal bis(guanylhydrazone) and related substances

1974 • 126 citations

Isolation of mutant mammalian cells altered in polyamine transport

1978 • 123 citations

Effect of methylglyoxal bis(guanylhydrazone) on polyamine metabolism in normal and regenerating rat liver and rat thymus

1973 • 119 citations

CURRENT STUDIES WITH METHYLGLYOXAL-BIS(GUANYLHYDRAZONE).

1963 • 73 citations

Carcinostatic action of polycarbonyl compounds and their derivatives. II. Glyoxal bis (guanylhydrazone) and derivatives.

1958 • 73 citations

Inhibitors of polyamine biosynthesis. 1. .alpha.-Methyl-(+-)-ornithine, an inhibitor of ornithine decarboxylase

1974 • 71 citations

Determination of polyamines in urine

1973 • 71 citations

The generality of methylglyoxal bis(guanylhydrazone)-induced mitochondrial damage and the dependence of this effect on cell proliferation.

1979 • 65 citations

S-adenosylmethionine decarboxylase from baker's yeast

1975 • 58 citations

Sensitive Enzymic determination of methylglyoxal bis(guanylhydrazone) in cultured cells and in animal tissues

1980 • 53 citations

Death of Tumor Cells in Response to the Use of a System of Stimulated Polyamine Uptake for the Transport of Methylglyoxal Bis(guanylhydrazone)

1981 • 50 citations

Correlation of ultrastructural and functional damage to mitochondria of ascites L1210 cells treated in vivo with methylglyoxal-bis(guanylhydrazone) or ethidium bromide.

1979 • 44 citations

Comparison of inhibitors of S-adenosylmethionine decarboxylase from different species

1983 • 40 citations

Relation of the Antiproliferative Action of Methylglyoxal‐bis(guanylhydrazone) to the Natural Polyamines

1980 • 39 citations

Dissociation of the early antiproliferative action of methylglyoxal bis(guanylhydrazone) from polyamine depletion

1979 • 37 citations

[40] Inhibitors of S-adenosylmethionine decarboxylase

1983 • 33 citations

Role of diamine oxidase during the treatment of tumour-bearing mice with combinations of polyamine anti-metabolites

1983 • 22 citations

Inhibition of S-adenosylmethionine decarboxylase and diamine oxidase activities by analogues of methylglyoxal bis(guanylhydrazone) and their cellular uptake during lymphocyte activation

1984 • 20 citations