Activity of SR 142801 at peripheral tachykinin receptors

SOME QUANTITATIVE USES OF DRUG ANTAGONISTS

1959 • 3,948 citations

Pharmacologic Analysis of Drug Receptor Interaction

1988 • 936 citations

A Potent Nonpeptide Antagonist of the Substance P (NK ₁ ) Receptor

1991 • 875 citations

Tachykinin receptors and tachykinin receptor antagonists

1993 • 649 citations

A potent and selective non-peptide antagonist of the neurokinin a (NK2) receptor

1992 • 441 citations

In vitro and in vivo biological activities of SR140333, a novel potent non-peptide tachykinin NK1 receptor antagonist

1993 • 376 citations

Search for a physiological role of substance P in gastrointestinal motility

1985 • 336 citations

Highly selective agonists for substance P receptor subtypes.

1986 • 316 citations

Pharmacologic analysis of drug-receptor interaction

1994 • 270 citations

Selective agonists for substance P and neurokinin receptors

1987 • 239 citations

SR 142801, The first potent non-peptide antagonist of the tachykinin NK3 receptor

1994 • 222 citations

Evidence that Acetylcholine Released by Gastrin and Related Polypeptides Contributes to their Effect on Gastrointestinal Motility

1973 • 217 citations

Neurokinin B is a preferred agonist for a neuronal substance P receptor and its action is antagonized by enkephalin.

1985 • 193 citations

Competitive antagonists discriminate between NK₂ tachykinin receptor subtypes

1990 • 174 citations

Tissue distribution and quantitation of the mRNAs for three rat tachykinin receptors

1990 • 172 citations

Neurokinin A (NK2) receptor revisited with SR 48968, a potent non-peptide antagonist

1992 • 171 citations

The rat isolated portal vein: a preparation sensitive to neurokinins, particularly neurokinin B

1987 • 144 citations

Evidence that the contractile response of the guinea‐pig ileum to capsaicin is due to release of substance P.

1982 • 118 citations

Scyliorhinin I and II: two novel tachykinins from dogfish gut

1986 • 117 citations

The site of action of capsaicin on the guinea-pig isolated ileum

1978 • 113 citations

In vivo and in vitro pharmacology of SR 48,968, a non-peptide tachykinin NK2 receptor antagonist

1993 • 82 citations

MEN 10,627, a novel polycyclic peptide antagonist of tachykinin NK2 receptors.

1994 • 71 citations

Two types of relaxation due to capsaicin in the guinea pig isolated ileum

1987 • 70 citations

Calcitonin gene-related peptide is a potent relaxant of intestinal muscle

1987 • 69 citations

How we describe competitive antagonists: three questions of usage

1991 • 64 citations

Evidence for neurokinin-3 receptor-mediated tachykinin release in the guinea-pig ileum

1987 • 61 citations

Influence of (±)-CP-96,345 and SR 48968 on electrical field stimulation of the isolated guinea-pig main bronchus

1992 • 55 citations

The Nonpeptide NK-2 Antagonist SR 48968 Is Also a NK-3 Antagonist in the Guinea Pig but Not in the Rat

1993 • 51 citations

The actions of receptor-selective substance P analogs on myenteric neurons: an electrophysiological investigation

1988 • 43 citations

Nitric oxide is the mediator of tachykinin NK3 receptor-induced relaxation in the circular muscle of the guinea-pig ileum

1993 • 41 citations

Neuropeptide K, scyliorhinin I and II: new tools in the tachykinin receptor field

1988 • 36 citations

Tachykinin NK3 receptor mediates NANC hyperpolarization and relaxation via nitric oxide release in the circular muscle of the guinea-pig colon

1994 • 31 citations

Antagonism of the effects of calcitonin gene-related peptide and of capsaicin on the guinea-pig isolated ileum by human α-calcitonin gene-related peptide(8–37)

1991 • 31 citations

The dogfish peptides scyliorhinin I and scyliorhinin II bind with differential selectivity to mammalian tachykinin receptors

1987 • 31 citations

Different mechanism of tachykinin NK2 receptor blockade by SR 48968 and MEN 10,627 in the guinea-pig isolated gallbladder and colon

1994 • 28 citations

Effects of capsaicin on myenteric neurons of the guinea pig ileum

1989 • 27 citations

Neurochemical evidence for the release of acetylcholine from the guinea-pig ileum myenteric plexus by capsaicin

1985 • 21 citations

Studies on the mechanism of the contractile action of rat calcitonin gene-related peptide and of capsaicin on the guinea-pig lleum: Effect of hCGRP (8–37) and CGRP tachyphylaxis

1993 • 18 citations

Mu and kappa opioid receptor modulation of 5-HT3 and NK-3 receptor-evoked release of acetylcholine from the guinea-pig ileum myenteric plexus

1991 • 15 citations