Scattered micrometastases visualized at the single‐cell level: Detection and re‐isolation of lacZ‐labeled metastasized lymphoma cells

A safe packaging line for gene transfer: separating viral genes on two different plasmids

1988 • 1,118 citations

Lineage analysis in the vertebrate nervous system by retrovirus-mediated gene transfer.

1987 • 881 citations

Fluorescence-activated cell analysis and sorting of viable mammalian cells based on beta-D-galactosidase activity after transduction of Escherichia coli lacZ.

1988 • 487 citations

Prediction of early relapse in patients with operable breast cancer by detection of occult bone marrow micrometastases.

1991 • 454 citations

Neurons and glia arise from a common progenitor in chicken optic tectum: demonstration with two retroviruses and cell type-specific antibodies.

1990 • 241 citations

Immunocytological detection of bone marrow micrometastasis in operable non-small cell lung cancer.

1993 • 170 citations

Cancer Progression and Growth: Relationship of Paracrine and Autocrine Growth Mechanisms to Organ Preference of Metastasis

1993 • 157 citations

A Novel Approach to the Generation and Identification of Experimental Hepatic Metastases in a Murine Model

1986 • 145 citations

Selection and Biologic Properties of Malignant Variants of a Murine Lymphosarcoma<xref ref-type="fn" rid="FN2">2</xref>

1978 • 138 citations

Bacterial lacZ gene as a highly sensitive marker to detect micrometastasis formation during tumor progression.

1990 • 111 citations

Prevention of metastatic spread by postoperative immunotherapy with virally modified autologous tumor cells. I. Parameters for optimal therapeutic effects

1986 • 109 citations

Shifts in Tumor Cell Phenotypes Induced by Signals from the Microenvironment

1980 • 105 citations

Antigenic variation in cancer metastasis: immune escape versus immune control

1982 • 95 citations

Quantitative demonstration of spontaneous metastasis by MCF-7 human breast cancer cells cotransfected with fibroblast growth factor 4 and LacZ.

1993 • 93 citations

Granulocyte colony-stimulating factor (G-CSF) gene transduction in murine adenocarcinoma drives neutrophil-mediated tumor inhibition in vivo. Neutrophils discriminate between G-CSF-producing and G-CSF-nonproducing tumor cells.

1992 • 88 citations

Exploiting the lacZ reporter gene for quantitative analysis of disseminated tumor growth within the brain: use of the lacZ gene product as a tumor antigen, for evaluation of antigenic modulation, and to facilitate image analysis of tumor growth in situ.

1993 • 59 citations

Protein-specific cytotoxic T lymphocytes. Recognition of transfectants expressing intracellular, membrane-associated or secreted forms of β-galactosidase

1989 • 59 citations

Modification of tumor cells by a low dose of Newcastle Disease Virus.

1988 • 51 citations

Regulation of tumor cell growth at organ-specific metastases.

1992 • 49 citations

Development of a lacZ marked WEHI-3B D+ murine leukemic cell line as an in-vivo model of acute non-lymphocytic leukemia.

1993 • 10 citations

Isolation and characterization of a low metastatic variant from EL-4 mouse T-lymphoma

1992 • 7 citations