Quantification of 3′OH DNA Breaks by Random Oligonucleotide-Primed Synthesis (ROPS) Assay

Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation.

1992 • 9,540 citations

A rapid, sensitive, and versatile assay for protein using Coomassie brilliant blue G250

1977 • 2,970 citations

Programmed cell death involved in the schizolysigenous formation of the secretory cavity in Citrus sinensis L. (Osbeck)

2010 • 1,629 citations

Detection of DNA strand breaks in individual apoptotic cells by the in situ terminal deoxynucleotidyl transferase and nick translation assays.

1993 • 997 citations

Breaks in genomic DNA and within the p53 gene are associated with hypomethylation in livers of folate/methyl-deficient rats.

1995 • 304 citations

Exonuclease III and endonuclease IV remove 3' blocks from DNA synthesis primers in H2O2-damaged Escherichia coli.

1986 • 270 citations

MAMMALIAN DNA LIGASES

1992 • 233 citations

Deoxyribonuclease I in mammalian tissues. Specificity of inhibition by actin.

1981 • 150 citations

Conformational changes of single-stranded DNA

1969 • 101 citations

Proofreading DNA: recognition of aberrant DNA termini by the Klenow fragment of DNA polymerase I.

1994 • 70 citations

DNA repair

1993 • 64 citations

Novel in situ double labeling for simultaneous detection of proliferation and apoptosis.

1994 • 51 citations

Major discrepancies between results obtained with two different methods for evaluating DNA damage: alkaline elution and alkaline unwinding. Possible explanations.

1987 • 39 citations

Influence of nucleotide sequence adjacent to duplex DNA termini on 3′ terminal labeling by terminal transferase

1979 • 29 citations

7 Terminal Deoxynucleotidyltransferase

1981 • 24 citations

REBASE — restriction enzymes and methylases

1994 • 22 citations

Inhibition of DNA synthesis and DNA fragmentation in stimulated splenocytes by the concerted action of topoisomerase I and II poisons

1993 • 18 citations

Induction of DNA Double-Strand Breaks by Restriction Enzymes in X-Ray-Sensitive Mutant Chinese Hamster Ovary Cells Measured by Pulsed-Field Gel Electrophoresis

1995 • 14 citations

Radioactive End Labeling to Determine Hydrolytic Rates of Nuclease Mimics

1994 • 9 citations

Simultaneous detection of DNA strand breaks and unscheduled DNA synthesis in mutagen-treated human lymphocytes in the absence of hydroxyurea

1988 • 6 citations

[Recognition of primers, containing noncomplementary nucleotides and units, lacking bases, by the Klenow fragment of Escherichia coli DNA polymerase I].

1993 • 1 citations