Intravenously injected insulin-like growth factor (IGF) I/IGF binding protein-3 complex exerts insulin-like effects in hypophysectomized, but not in normal rats.

Analysis of serum insulin-like growth factor binding proteins using Western blotting: Use of the method for titration of the binding proteins and competitive binding studies

1986 • 1,158 citations

Radioimmunological determination of insulinlike growth factors I and II in normal subjects and in patients with growth disorders and extrapancreatic tumor hypoglycemia.

1981 • 595 citations

Short-Term Metabolic Effects of Recombinant Human Insulin-like Growth Factor I in Healthy Adults

1987 • 554 citations

Insulin-like growth factors I and II in healthy man.

1989 • 513 citations

Recombinant human insulin-like growth factor I stimulates growth and has distinct effects on organ size in hypophysectomized rats.

1988 • 424 citations

Direct Demonstration of Separate Receptors for Growth and Metabolic Activities of Insulin and Multiplication-stimulating Activity (an Insulinlike Growth Factor) Using Antibodies to the Insulin Receptor

1980 • 346 citations

Structure of the Mr 140,000 growth hormone-dependent insulin-like growth factor binding protein complex: determination by reconstitution and affinity-labeling.

1989 • 308 citations

Acute metabolic effects and half-lives of intravenously administered insulinlike growth factors I and II in normal and hypophysectomized rats.

1986 • 306 citations

Acute effects of insulin-like growth factor I on glucose and amino acid metabolism in the awake fasted rat. Comparison with insulin.

1989 • 294 citations

1 Biological and immunological properties of insulin-like growth factors (IGF) I and II

1984 • 279 citations

INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN-1 MODULATES BLOOD GLUCOSE LEVELS

1991 • 262 citations

Characterization of the Acid-Labile Subunit of the Growth Hormone-Dependent Insulin-Like Growth Factor Binding Protein Complex*

1988 • 239 citations

Recombinant human insulin-like growth factor I induces its own specific carrier protein in hypophysectomized and diabetic rats.

1989 • 221 citations

Insulin-Like Growth Factor (IGF) and IGF-Binding Proteins: Comparison of Human Serum and Lymph*

1988 • 216 citations

Can "big" insulin-like growth factor II in serum of tumor patients account for the development of extrapancreatic tumor hypoglycemia?

1992 • 168 citations

Regulation of binding proteins for insulin-like growth factors (IGF) in humans. Increased expression of IGF binding protein 2 during IGF I treatment of healthy adults and in patients with extrapancreatic tumor hypoglycemia.

1990 • 148 citations

Effect of Trypsin Treatment of Rat Adipocytes on Biological Effects and Binding of Insulin and Insulin‐Like Growth Factors

1981 • 143 citations

Significance of abnormal serum binding of insulin-like growth factor II in the development of hypoglycemia in patients with non-islet-cell tumors.

1989 • 139 citations

Further Characterization of Growth Hormone-Dependent Somatomedin-Binding Proteins in Rat Serum and Demonstration of Somatomedin-Binding Proteins Produced by Rat Liver Cells in Culture*

1979 • 138 citations

Intact but not truncated insulin-like growth factor binding protein-3 (IGFBP-3) blocks IGF I-induced stimulation of osteoblasts: Control of IGF signalling to bone cells by IGFBP-3-specific proteolysis?

1991 • 123 citations

Isolation from adult human serum of four insulin-like growth factor (IGF) binding proteins and molecular cloning of one of them that is increased by IGF I administration and in extrapancreatic tumor hypoglycemia.

1990 • 114 citations

Identification and molecular cloning of two new 30-kDa insulin-like growth factor binding proteins isolated from adult human serum

1991 • 109 citations

Impaired Formation of the Ternary Insulin-Like Growth Factor-Binding Protein Complex in Patients with Hypoglycemia due to Nonislet Cell Tumors*

1991 • 105 citations

Serum "big insulin-like growth factor II" from patients with tumor hypoglycemia lacks normal E-domain O-linked glycosylation, a possible determinant of normal propeptide processing.

1993 • 99 citations

Bioavailability of insulin-like growth factors (IGFs) in rats determined by the molecular distribution of human IGF-binding protein-3.

1993 • 67 citations

Tissue Localization of Perfused Endothelial Cell IGF Binding Protein is Markedly Altered by Association with IGF-I

1990 • 46 citations

Effects of Insulin on Glucose Metabolism and Glucose Transport in Fat Cells of Hormone-Treated Hypophysectomized Rats: Evidence That Growth Hormone Restricts Glucose Transport*

1979 • 43 citations

Properties of glycosylated and non-glycosylated human recombinant IGF binding protein-3 (IGFBP-3).

1993 • 37 citations

Synthesis of the acid-labile subunit of the growth-hormone-dependent insulin-like-growth-factor-binding protein complex by rat hepatocytes in culture

1991 • 34 citations

Bioavailability of insulin-like growth factors (IGFs) in rats determined by the molecular distribution of human IGF-binding protein-3

1993 • 29 citations

Comparison of Somatomedin Activity in Rat Serum and Lymph¹

1975 • 25 citations

Effect of insulin on glucose transport and metabolism in adipose tissue and skeletal muscle of hypophysectomized rats

1981 • 15 citations