Nm23 and breast cancer metastasis

Cancer metastasis and angiogenesis: An imbalance of positive and negative regulation

1991 • 2,774 citations

Evidence for a Novel Gene Associated With Low Tumor Metastatic Potential

1988 • 1,304 citations

Tumorigenicity and metastasis of human breast carcinoma cell lines in nude mice.

1990 • 617 citations

Tumor interactions with the vasculature: angiogenesis and tumor metastasis

1990 • 598 citations

Cancer metastasis

1982 • 567 citations

Reduced tumor incidence, metastatic potential, and cytokine responsiveness of nm3-transfected melanoma cells

1991 • 548 citations

Reduced Nm23/Awd protein in tumour metastasis and aberrant Drosophila development

1989 • 487 citations

Nucleoside diphosphate kinase from human erythrocytes. Structural characterization of the two polypeptide chains responsible for heterogeneity of the hexameric enzyme

1991 • 420 citations

Association of low nm23 RNA levels in human primary infiltrating ductal breast carcinomas with lymph node involvement and other histopathological indicators of high metastatic potential.

1989 • 398 citations

Identification of a second human nm23 gene, nm23-H2.

1991 • 357 citations

A Drosophila gene that is homologous to a mammalian gene associated with tumor metastasis codes for a nucleoside diphosphate kinase

1990 • 353 citations

Expression of the Antimetastatic Gene nm23 in Human Breast Cancer: An Association WIth Good Prognosis

1991 • 298 citations

Transfection of human nm23-H1 into the human MDA-MB-435 breast carcinoma cell line: effects on tumor metastatic potential, colonization and enzymatic activity.

1993 • 298 citations

9 Nucleoside Diphosphokinases

1973 • 274 citations

High levels of p19/nm23 protein in neuroblastoma are associated with advanced stage disease and with N-myc gene amplification.

1991 • 229 citations

Evidence for nm23 RNA overexpression, DNA amplification and mutation in aggressive childhood neuroblastomas.

1993 • 203 citations

Levels of nm23 messenger RNA in metastatic malignant melanomas: inverse correlation to disease progression.

1992 • 197 citations

X-ray structure of nucleoside diphosphate kinase.

1992 • 191 citations

Growth Dominance of the Metastatic Cancer Cell: Cellular and Molecular Aspects

1990 • 179 citations

Low nm23 protein expression in infiltrating ductal breast carcinomas correlates with reduced patient survival.

1991 • 166 citations

Developmental consequences of awdb3, a cell-autonomous lethal mutation of Drosophila induced by hybrid dysgenesis

1988 • 162 citations

Somatic allelic deletion of nm23 in human cancer.

1991 • 159 citations

Induction of nm23 Gene Expression in Human Colonic Neoplasms and Equal Expressions in Colon Tumors of High and Low Metastatic Potential

1991 • 157 citations

Expression in Human Hepatocellular Carcinoma of Nucleoside Diphosphate Kinase, a Homologue of the nm23 Gene Product

1992 • 157 citations

Proliferation-related expression of p19/nm23 nucleoside diphosphate kinase.

1992 • 149 citations

Association of nm23-H1 allelic deletions with distant metastases in colorectal carcinoma

1991 • 135 citations

Positive Relationship Between Expression of Anti-metastatic Factor (nm23 Gene Product or Nucleoside Diphosphate Kinase) and Good Prognosis in Human Breast Cancer

1991 • 132 citations

Cell Growth and Differentiation

2004 • 124 citations

Conversion of GDP into GTP by nucleoside diphosphate kinase on the GTP-binding proteins.

1990 • 121 citations

The microtubule-associated nucleoside diphosphate kinase.

1984 • 120 citations

Nm23 Protein Expression in Ductal In Situ and Invasive Human Breast Carcinoma

1993 • 119 citations

Loss of growth factor dependence and conversion of transforming growth factor-beta 1 inhibition to stimulation in metastatic H-ras-transformed murine fibroblasts.

1988 • 113 citations

Identity of a differentiation inhibiting factor for mouse myeloid leukemia cells with NM23/nucleoside diphosphate kinase

1992 • 113 citations

Overexpression of nucleoside diphosphate kinase (nm23) in solid tumours

1991 • 110 citations

Nucleoside diphosphate kinase/NM23 expression in breast cancer: Lack of correlation with lymph‐node metastasis

1992 • 100 citations

Molecular consequences of awdb3, a cell-autonomous lethal mutation of Drosophila induced by hybrid dysgenesis

1988 • 98 citations

Embryonic expression of nm23 during mouse organogenesis.

1992 • 97 citations

Activation of a Small GTP-Binding Protein by Nucleoside Diphosphate Kinase

1991 • 81 citations

Immunohistochemical analysis of nm23 gene product/NDP kinase expression in pulmonary adenocarcinoma: lack of prognostic value

1992 • 75 citations

Regulatory GTP-binding proteins (ADP-ribosylation factor, Gt, and RAS) are not activated directly by nucleoside diphosphate kinase.

1992 • 75 citations

The molecular biology of breast cancer

1991 • 74 citations

Molecular cloning and functional expression of the second mouse nm23/NDP kinase gene, nm23‐M2

1992 • 71 citations

A product of the prune locus of Drosophila is similar to mammalian GTPase-activating protein

1991 • 70 citations

The Expression of the Drosophila awd Gene during Normal Development and in Neoplastic Brain Tumors Caused by lgl Mutations

1993 • 50 citations

Expression level of the nm23 gene in clonal populations of metastatic murine and human neoplasms.

1992 • 38 citations

Nucleoside diphosphate kinase does not directly interact with tubulin nor microtubules

1992 • 33 citations

The human NME2 gene lies within 18kb of NME1 in chromosome 17

1993 • 26 citations

Nucleoside diphosphate kinases, nm23, and tumor metastasis: Possible biochemical mechanisms

1993 • 26 citations

Decreasing expression of NM23 gene in metastatic murine mammary tumors of viral etiology (MMTV).

1992 • 17 citations

Genetic control of the metastatic phenotype.

1991 • 16 citations

Nucleoside diphosphokinase and cell cycle control in the fission yeast Schizosaccharomyces pombe

1983 • 13 citations

Genetic control of the metastatic phenotype.

1991 • 6 citations