Control of astrocyte Ca2+ oscillations and waves by oscillating translocation and activation of protein kinase C

Protein kinase C and lipid signaling for sustained cellular responses

1995 • 2,527 citations

Glutamate Induces Calcium Waves in Cultured Astrocytes: Long-Range Glial Signaling

1990 • 1,820 citations

Glutamate-mediated astrocyte–neuron signalling

1994 • 1,688 citations

Prostaglandins stimulate calcium-dependent glutamate release in astrocytes

1998 • 1,138 citations

Imaging of single fluorescent molecules and individual ATP turnovers by single myosin molecules in aqueous solution

1995 • 1,029 citations

Direct Signaling from Astrocytes to Neurons in Cultures of Mammalian Brain Cells

1994 • 1,000 citations

Neuronal activity triggers calcium waves in hippocampal astrocyte networks

1992 • 818 citations

Cell-substrate contacts illuminated by total internal reflection fluorescence.

1981 • 804 citations

Connexins regulate calcium signaling by controlling ATP release

1998 • 767 citations

Intercellular signaling in glial cells: Calcium waves and oscillations in response to mechanical stimulation and glutamate

1991 • 723 citations

Intracellular calcium oscillations in astrocytes: a highly plastic, bidirectional form of communication between neurons and astrocytes in situ.

1997 • 711 citations

Protein Kinase C as a Molecular Machine for Decoding Calcium and Diacylglycerol Signals

1998 • 646 citations

Crystal structure of the Cys2 activator-binding domain of protein kinase Cδ in complex with phorbol ester

1995 • 643 citations

Intracellular Calcium Oscillations in Astrocytes: A Highly Plastic, Bidirectional Form of Communication between Neurons and AstrocytesIn Situ

1997 • 626 citations

Minimal model for signal-induced Ca2+ oscillations and for their frequency encoding through protein phosphorylation.

1990 • 626 citations

New insights into the regulation of protein kinase C and novel phorbol ester receptors

1999 • 600 citations

Hippocampal Astrocytes In Situ Respond to Glutamate Released from Synaptic Terminals

1996 • 560 citations

Hippocampal AstrocytesIn SituRespond to Glutamate Released from Synaptic Terminals

1996 • 542 citations

Glutamate-dependent astrocyte modulation of synaptic transmission between cultured hippocampal neurons

1998 • 532 citations

Spatiotemporal Dynamics of Inositol 1,4,5-Trisphosphate That Underlies Complex Ca ²⁺ Mobilization Patterns

1999 • 500 citations

Molecular model for receptor-stimulated calcium spiking.

1988 • 416 citations

Cooking with Calcium: The Recipes for Composing Global Signals from Elementary Events

1997 • 367 citations

Green Fluorescent Protein (GFP)-tagged Cysteine-rich Domains from Protein Kinase C as Fluorescent Indicators for Diacylglycerol Signaling in Living Cells

1998 • 331 citations

Ca2+ bridges the C2 membrane-binding domain of protein kinase Cα directly to phosphatidylserine

1999 • 321 citations

Spatial Sensing in Fibroblasts Mediated by 3′ Phosphoinositides

2000 • 300 citations

Control of calcium oscillations by phosphorylation of metabotropic glutamate receptors

1996 • 289 citations

Direct Visualization of the Translocation of the γ-Subspecies of Protein Kinase C in Living Cells Using Fusion Proteins with Green Fluorescent Protein

1997 • 228 citations

Termination of cytosolic Ca2+ signals: Ca2+ reuptake into intracellular stores is regulated by the free Ca2+ concentration in the store lumen

1998 • 228 citations

The last few milliseconds in the life of a secretory granule

1998 • 179 citations

A versatile microporation technique for the transfection of cultured CNS neurons

1999 • 139 citations

The Metabotropic Glutamate Receptor mGluR5 Induces Calcium Oscillations in Cultured Astrocytes via Protein Kinase C Phosphorylation

1997 • 138 citations

Lateral inhibition of inositol 1,4,5-trisphosphate receptors by cytosolic Ca2+

1999 • 137 citations

Calcium signalling

1999 • 136 citations

Ca2+-sensor region of IP3 receptor controls intracellular Ca2+ signaling

2001 • 131 citations

Protein Kinase C and A₃Adenosine Receptor Activation Inhibit Presynaptic Metabotropic Glutamate Receptor (mGluR) Function and Uncouple mGluRs from GTP-Binding Proteins

1998 • 124 citations

Visualization of Dynamic Trafficking of a Protein Kinase C βII/Green Fluorescent Protein Conjugate Reveals Differences in G Protein-coupled Receptor Activation and Desensitization

1998 • 105 citations

Elementary Calcium-Release Units Induced by Inositol Trisphosphate

1997 • 105 citations

Sinusoidal oscillations in intracellular calcium requiring negative feedback by protein kinase C.

1993 • 103 citations

Molecular Mechanism of the Inhibition of Phospholipase C β3 by Protein Kinase C

2000 • 83 citations

Diversity of Calcium Signaling by Metabotropic Glutamate Receptors

1998 • 77 citations

Nonlinear propagation of agonist‐induced cytoplasmic calcium waves in single astrocytes

1994 • 73 citations

Simultaneous visualization of the translocation of protein kinase Cα–green fluorescent protein hybrids and intracellular calcium concentrations

1999 • 54 citations