Regulatory factor-X binding to mutant HLA-DRA promoter sequences

A bacteriophage T7 RNA polymerase/promoter system for controlled exclusive expression of specific genes.

1985 • 3,185 citations

A multiplicity of CCAAT box-binding proteins

1987 • 745 citations

A High-Efficiency HeLa Cell Nuclear Transcription Extract

1988 • 612 citations

Immune interferon activates multiple class II major histocompatibility complex genes and the associated invariant chain gene in human endothelial cells and dermal fibroblasts.

1984 • 579 citations

Immunology: The ins and outs of antigen processing and presentations

1986 • 498 citations

Regulation of Major Histocompatibility Complex Class-II Genes: X, Y and Other Letters of the Alphabet

1990 • 470 citations

HLA class II induction in human islet cells by interferon-γ plus tumour necrosis factor or lymphotoxin

1987 • 451 citations

Increased expression of Ia antigens on resting B cells: an additional role for B-cell growth factor.

1984 • 438 citations

Interleukin-induced increase in Ia expression by normal mouse B cells.

1984 • 293 citations

A New Member of the Leucine Zipper Class of Proteins that Binds to the HLA DRα Promoter

1990 • 286 citations

Congenital immunodeficiency with a regulatory defect in MHC class II gene expression lacks a specific HLA-DR promoter binding protein, RF-X

1988 • 275 citations

mXBP/CRE-BP2 and c-Jun form a complex which binds to the cyclic AMP, but not to the 12-O-tetradecanoylphorbol-13-acetate, response element.

1990 • 237 citations

Conserved major histocompatibility complex class II boxes--X and Y--are transcriptional control elements and specifically bind nuclear proteins.

1987 • 212 citations

The T-cell repertoire for antigen and MHC

1988 • 180 citations

MHC class II regulatory factor RFX has a novel DNA-binding domain and a functionally independent dimerization domain.

1990 • 171 citations

Regulation of a transfected human class II major histocompatibility complex gene in human fibroblasts.

1986 • 159 citations

Cloning of the major histocompatibility complex class II promoter binding protein affected in a hereditary defect in class II gene regulation.

1989 • 141 citations

Combined immunodeficiency with defective expression in MHC class II genes.

1989 • 131 citations

Upstream DNA sequences required for tissue-specific expression of the HLA-DR alpha gene.

1987 • 126 citations

Mutational analysis of the DRA promoter: cis-acting sequences and trans-acting factors.

1990 • 121 citations

B-cell-specific and interferon-gamma-inducible regulation of the HLA-DR alpha gene.

1988 • 118 citations

A complete library of point substitution mutations in the glucocorticoid response element of mouse mammary tumor virus.

1986 • 114 citations

Interaction of the lymphocyte-derived Epstein-Barr virus nuclear antigen EBNA-1 with its DNA-binding sites

1989 • 107 citations

Detailed delineation of an interferon-gamma-responsive element important in human HLA-DRA gene expression in a glioblastoma multiform line.

1988 • 101 citations

Structure and expression of HLA-DQ ? and -DX ? genes: interallelic alternate splicing of the HLA-DQ ? gene and functional splicing of the HLA-DX ? gene using a retroviral vector

1987 • 80 citations

Organization of the transcriptional unit of a human class II histocompatibility antigen: HLA-DR heavy chain

1983 • 79 citations

Molecular Genetics of the Human Major Histocompatibility Complex

1986 • 78 citations

B-Cell Control Region at the 5′ End of a Major Histocompatibility Complex Class II Gene: Sequences and Factors

1988 • 71 citations

Sequence Elements Required for Activity of a Murine Major Histocompatibility Complex Class II Promoter Bind Common and Cell-Type-Specific Nuclear Factors

1990 • 68 citations

Two DNA-binding proteins discriminate between the promoters of different members of the major histocompatibility complex class II multigene family.

1990 • 66 citations

Class II box consensus sequences in the HLA-DR alpha gene: transcriptional function and interaction with nuclear proteins.

1989 • 63 citations

mXBP/CRE-BP2 and c-Jun Form a Complex Which Binds to the Cyclic AMP, but Not to the 12-O-Tetradecanoylphorbol-13-Acetate, Response Element

1990 • 56 citations

Conserved upstream sequences of human class II major histocompatibility genes enhance expression of class II genes in wild-type but not mutant B-cell lines.

1988 • 51 citations

B-cell-specific enhancer activity of conserved upstream elements of the class II major histocompatibility complex DQB gene.

1988 • 49 citations

Class II Box Consensus Sequences in the HLA-DRα Gene: Transcriptional Function and Interaction with Nuclear Proteins

1989 • 34 citations

Evidence for a trans-acting factor that regulates the transcription of class II major histocompatibility complex genes: genetic and functional analysis.

1988 • 31 citations

Two DNA-Binding Proteins Discriminate between the Promoters of Different Members of the Major Histocompatibility Complex Class II Multigene Family

1990 • 28 citations

Sequence Analysis of the Human Major Histocompatibility Gene SXα

1985 • 27 citations

The Molecular Basis of MHC-Restricted Antigen Recognition by T Cells

1988 • 6 citations