Public health implications from COGS and potential for risk stratification and screening

Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing

2008 • 3,615 citations

Average Risks of Breast and Ovarian Cancer Associated with BRCA1 or BRCA2 Mutations Detected in Case Series Unselected for Family History: A Combined Analysis of 22 Studies

2003 • 3,497 citations

Sick Individuals and Sick Populations

1985 • 2,425 citations

The benefits and harms of breast cancer screening: an independent review

2012 • 1,358 citations

Breast Cancer in Young Women: Poor Survival Despite Intensive Treatment

2009 • 462 citations

The genome of the hydatid tapeworm Echinococcus granulosus

2013 • 281 citations

Functional Variants at the 11q13 Risk Locus for Breast Cancer Regulate Cyclin D1 Expression through Long-Range Enhancers

2013 • 204 citations

Genome-wide association analyses in east Asians identify new susceptibility loci for colorectal cancer

2012 • 180 citations

Treatment and survival outcomes in young men diagnosed with prostate cancer

2009 • 162 citations

Polygenic susceptibility to prostate and breast cancer: implications for personalised screening

2011 • 156 citations

Fine-mapping identifies multiple prostate cancer risk loci at 5p15, one of which associates with TERT expression

2013 • 107 citations

Epithelial Pten is dispensable for intestinal homeostasis but suppresses adenoma development and progression after Apc mutation

2008 • 105 citations

Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31

2013 • 105 citations

Stratified Cancer Screening: The Practicalities of Implementation

2013 • 45 citations

Building the evidence base for decision making in cancer genomic medicine using comparative effectiveness research

2012 • 35 citations