Insulin and glucose modulate protein kinase C activity in rat adipocytes

Insulin-stimulated translocation of glucose transport systems in the isolated rat adipose cell. Time course, reversal, insulin concentration dependency, and relationship to glucose transport activity.

1981 • 456 citations

The Molecular Mechanism of Insulin Action

1985 • 424 citations

Phospholipids and cellular regulation

1985 • 331 citations

Ia binding ligands and cAMP stimulate nuclear translocation of PKC in B lymphocytes

1987 • 321 citations

Phorbol ester-induced serine phosphorylation of the insulin receptor decreases its tyrosine kinase activity.

1988 • 315 citations

[31] Calcium-activated, phospholipid-dependent protein kinase (protein kinase C) from rat brain

1983 • 281 citations

The existence of an optimal range of cytosolic free calcium for insulin-stimulated glucose transport in rat adipocytes.

1987 • 230 citations

Affinity chromatography of protein kinase C-phorbol ester receptor on polyacrylamide-immobilized phosphatidylserine.

1984 • 205 citations

Insulin Rapidly Increases Diacylglycerol by Activating De Novo Phosphatidic Acid Synthesis

1987 • 200 citations

Glucose and insulin co-regulate the glucose transport system in primary cultured adipocytes. A new mechanism of insulin resistance.

1987 • 180 citations

Insulin increases membrane and cytosolic protein kinase C activity in BC3H-1 myocytes.

1987 • 171 citations

Insulin increases membrane protein kinase C activity in rat diaphragm

1987 • 65 citations

Starvation-induced changes of palmitate metabolism and insulin secretion in isolated rat islets stimulated by glucose

1984 • 63 citations

Phorbol esters, but not insulin, promote depletion of cytosolic protein kinase C in rat adipocytes

1986 • 62 citations

Phorbol esters, but not epidermal growth factor or insulin, rapidly decrease soluble protein kinase C activity in rat hepatocytes

1986 • 47 citations

Insulin-dependent alterations of phorbol ester binding to adipocyte subcellular constituents. Evidence for the involvement of protein kinase C in insulin action

1987 • 31 citations